Zobrazeno 1 - 10
of 421
pro vyhledávání: '"Mandigers, P."'
Autor:
Jonathan E. Knikman, Qinglian Zhai, Carin A. T. C. Lunenburg, Linda M. Henricks, Stefan Böhringer, Maaike van der Lee, Femke M. de Man, Steven M. Offer, Shikshya Shrestha, Geert-Jan Creemers, Arnold Baars, Vincent O. Dezentjé, Alexander L. T. Imholz, Frank J. F. Jeurissen, Johanna E. A. Portielje, Rob L. H. Jansen, Paul Hamberg, Helga J. Droogendijk, Miriam Koopman, Peter Nieboer, Marlène H. W. van de Poel, Caroline M. P. W. Mandigers, Ron H. N. van Schaik, Hans Gelderblom, Ron H. J. Mathijssen, Jan H. M. Schellens, Annemieke Cats, Henk-Jan Guchelaar, Jesse J. Swen
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-11 (2024)
Abstract Background The Alpe-DPD study (NCT02324452) demonstrated that prospective genotyping and dose-individualization using four alleles in DPYD (DPYD*2A/rs3918290, c.1236G > A/rs75017182, c.2846A > T/rs67376798 and c.1679 T > G/rs56038477) can mi
Externí odkaz:
https://doaj.org/article/b16be71c28a348628ff01bad41681526
Autor:
Paul J. J. Mandigers, Simone E. Meijs, Marta Plonek, Koen M. Santifort, M. Montserrat Diaz Espineira
Publikováno v:
Frontiers in Veterinary Science, Vol 11 (2024)
IntroductionIdiopathic epilepsy (IE) is a common chronic neurological disorder in dogs. Breed specific knowledge on semiology, age of onset (AoO), seizure frequency, response to treatment, and Quality of Life (QoL) scores for both dog and owner are i
Externí odkaz:
https://doaj.org/article/92f838a8d55c4adda2bd54576202cbef
Publikováno v:
Frontiers in Veterinary Science, Vol 11 (2024)
Paroxysmal dyskinesias (PDs) are a group of involuntary, hyperkinetic movement disorders that recur episodically and may last seconds to hours. An important feature of PD is that there is no loss of consciousness during the episode. Using a clinical
Externí odkaz:
https://doaj.org/article/df3cb6fed28d412096b44ee59d1f1130
Autor:
Tim J. Mandigers, MD, Ariel F. Pascaner, PhD, Michele Conti, PhD, Martina Schembri, MS, Sonja Jelic, BS, Alessandra Favilli, DVM, Daniele Bissacco, MD, Maurizio Domanin, MD, Joost A. van Herwaarden, MD, PhD, Ferdinando Auricchio, PhD, Santi Trimarchi, MD, PhD
Publikováno v:
JTCVS Open, Vol 17, Iss , Pp 37-46 (2024)
Objective: The relationship among increased aortic arch angulation, aortic flow dynamics, and vessel wall stiffness remains unclear. This experimental ex vivo study investigated how increased aortic arch angulation affects aortic stiffness and stent-
Externí odkaz:
https://doaj.org/article/15ffd007d97542c08629282fb04c8d88
Publikováno v:
Frontiers in Veterinary Science, Vol 11 (2024)
Bromide is the first effective antiseizure medication used in human medicine since the XIX century. Initially met with skepticism, bromide quickly gained enthusiasm within the medical field until being largely replaced by newer antiseizure medication
Externí odkaz:
https://doaj.org/article/b165194d52bf4b48a66835549ada79d7
Publikováno v:
Frontiers in Veterinary Science, Vol 11 (2024)
IntroductionChiari-like malformation (CM) and syringomyelia (SM) are disorders that, in dogs, affect mainly small and toy breeds, including the Pomeranian. These disorders are linked to a great number of (owner-reported) clinical signs (ORCS) suggest
Externí odkaz:
https://doaj.org/article/eb8ea3d31c484fc7837e0c319c4d644c
Autor:
Vanessa Alf, Yvet Opmeer, G. Diane Shelton, Guy C. M. Grinwis, Kaspar Matiasek, Marco Rosati, Paul J. J. Mandigers
Publikováno v:
Animals, Vol 14, Iss 17, p 2519 (2024)
Earlier, we described a breed-specific inflammatory myopathy in Dutch Kooiker dogs (Het Nederlandse Kooikerhondje), one of the nine Dutch breeds. The disease commonly manifests itself with clinical signs of difficulty walking, muscle weakness, exerci
Externí odkaz:
https://doaj.org/article/eb2bf37bd4d648b3adfa219a83458ff4
Publikováno v:
PLoS ONE, Vol 19, Iss 11, p e0313203 (2024)
Studies in Pomeranians as well as other breeds have looked at clinical signs or external features as predictors of Chiari-like malformation (CM) and syringomyelia (SM). The aim of this study is to describe and analyze morphometric factors of the skul
Externí odkaz:
https://doaj.org/article/8eb85caaa8f84ce8a28cc1871a3ebe43
Autor:
Tim Mandigers, Ariel Pascaner, Michele Conti, Martina Schembri, Sonja Jelic, Daniele Bissacco, Maurizio Domanin, Joost Van Herwaarden, Ferdinando Auricchio, Santi Trimarchia
Publikováno v:
EJVES Vascular Forum, Vol 61, Iss , Pp S24- (2024)
Externí odkaz:
https://doaj.org/article/7e02873175274adea0fe0f2c04a582ea
Publikováno v:
Frontiers in Veterinary Science, Vol 11 (2024)
IntroductionSyringomyelia (SM) is a heritable disorder causing a fluid filled cavity (FFC) in the spinal cord with a reported overall prevalence of 39 to 46% in the Cavalier King Charles Spaniels (CKCS). Breeders started screening their CKCS with MRI
Externí odkaz:
https://doaj.org/article/2c8c0f85f8eb4e01932819679a006e08