Výsledky vyhledávání - "Mandi M. Murph"

Supplementary Data 5 from miR-122-5p Expression and Secretion in Melanoma Cells Is Amplified by the LPAR3 SH3–Binding Domain to Regulate Wnt1

Autor: Mandi M. Murph, Sudeepti S. Kuppa, Ali A. Alshamrani, Wei Jia, Charnel C. Byrnes

Supplementary Figure 5. miR-122-5p abundance fluctuates in heart tissue, resultant from LPAR3 expression. Tissues were collected from knock-out mice lacking the first exon of the LPAR3 and their wild-type siblings and assessed for miR-122-5p and LPAR

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d280cb1698094b08319c3b34e89ec02
https://doi.org/10.1158/1541-7786.22515406

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Data from miR-122-5p Expression and Secretion in Melanoma Cells Is Amplified by the LPAR3 SH3–Binding Domain to Regulate Wnt1

Autor: Mandi M. Murph, Sudeepti S. Kuppa, Ali A. Alshamrani, Wei Jia, Charnel C. Byrnes

The lysophosphatidic acid receptor-3 (LPAR3) is a G protein–coupled receptor that mediates viability among malignant cells and aggressiveness among certain tumors. The study's objective was to determine the interplay between LPAR3 and miRNAs to imp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::401b0680c5513cb45b867cc8a732d6d6
https://doi.org/10.1158/1541-7786.c.6541081

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Supplementary Data 3B from miR-122-5p Expression and Secretion in Melanoma Cells Is Amplified by the LPAR3 SH3–Binding Domain to Regulate Wnt1

Autor: Mandi M. Murph, Sudeepti S. Kuppa, Ali A. Alshamrani, Wei Jia, Charnel C. Byrnes

Supplementary Figure 3. Microfluidics visualization of nanoparticles from LPAR3. The movies illustrate the difference between the smaller/almost indiscernible white dots, which are exosome nanoparticles, secreted by cells expressing LPAR3-wt versus t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30e95b3abb546c1f361606d3ab15305c
https://doi.org/10.1158/1541-7786.22515415

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Supplementary Data 4 from miR-122-5p Expression and Secretion in Melanoma Cells Is Amplified by the LPAR3 SH3–Binding Domain to Regulate Wnt1

Autor: Mandi M. Murph, Sudeepti S. Kuppa, Ali A. Alshamrani, Wei Jia, Charnel C. Byrnes

Supplementary Figure 4. Comparison of exogenously-added reagents. The qRT-PCR results display the relative abundance of miR-122-5p with no treatment (untreated) versus DharmaFECT alone, miR-122-5p mimic and miR-122-5p antagomir. The latter shows an u

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31aa00376f79de8c97f9ee69ba363a47
https://doi.org/10.1158/1541-7786.22515409.v1

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Supplementary Data 1 from miR-122-5p Expression and Secretion in Melanoma Cells Is Amplified by the LPAR3 SH3–Binding Domain to Regulate Wnt1

Autor: Mandi M. Murph, Sudeepti S. Kuppa, Ali A. Alshamrani, Wei Jia, Charnel C. Byrnes

Supplementary Figure 1. MiR-122-5p-5p is increased in the serum of cancer patients. The NCBI Gene Expression Omnibus DataSets (GSE106817) was downloaded and mined for the relative expression of miR-122-5p-5p among the circulation of health subjects (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::000b6702e2973aa22c8e1aef180422d9
https://doi.org/10.1158/1541-7786.22515424.v1

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Are we there yet? A machine learning architecture to predict organotropic metastases

Autor: Michael Skaro, Marcus Hill, Jonathan Arnold, Yi Zhou, Mandi M. Murph, Andrea Sboner, Shannon Quinn, Melissa Davis

Publikováno v: BMC Medical Genomics
BMC Medical Genomics, Vol 14, Iss 1, Pp 1-11 (2021)

Background & Aims Cancer metastasis into distant organs is an evolutionarily selective process. A better understanding of the driving forces endowing proliferative plasticity of tumor seeds in distant soils is required to develop and adapt better tre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f6b710da5207490da63bdab51d45f06
http://europepmc.org/articles/PMC8611885

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Akademický článek

Lysophosphatidic Acid Mediates Activating Transcription Factor 3 Expression Which Is a Target for Post-Transcriptional Silencing by miR-30c-2-3p.

Autor: Ha T Nguyen, Wei Jia, Aaron M Beedle, Eileen J Kennedy, Mandi M Murph

Publikováno v: PLoS ONE, Vol 10, Iss 9, p e0139489 (2015)

Although microRNAs (miRNAs) are small, non-protein-coding entities, they have important roles in post-transcriptional regulation of most of the human genome. These small entities generate fine-tuning adjustments in the expression of mRNA, which can m

Externí odkaz: https://doaj.org/article/b55b61ba925447adaf841da361bfa136

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Ovarian cysts and granulosa cell tumors develop after sublethal total body irradiation in mice

Autor: Mandi M. Murph, Yao Xiao, Nancy R. Manley, Xiaohong Xu, Shiyun Xiao, Wen Zhang

BackgroundLocalized and total body irradiation are used to treat certain cancers and also used prior to transplantation of stem cells or organs. However, the use of radiation also induces collateral damage to the cells of healthy tissue. Although the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a4fd9ab6f90f029d4a7d37a64e17f1d1
https://doi.org/10.1101/2021.07.08.450892

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