Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Mandi M. Hopkins"'
Autor:
Stephen Quirk, Mandi M. Hopkins, Hailey Bureau, Ryan J. Lusk, Caley Allen, Rigoberto Hernandez, David L. Bain
Publikováno v:
ACS Omega, Vol 3, Iss 2, Pp 2141-2154 (2018)
Externí odkaz:
https://doaj.org/article/c4838f59690f48d89023267fae8e0533
Publikováno v:
Pharmaceutical Research.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da320722361a9123c0f889d8b8662f64
https://doi.org/10.1007/s11095-023-03485-1
https://doi.org/10.1007/s11095-023-03485-1
Publikováno v:
Pharmaceutical Research. 38:243-255
Reversible self-association (RSA) remains a challenge in the development of therapeutic monoclonal antibodies (mAbs). We recently analyzed the energetics of RSA for five IgG mAbs (designated as A-E) under matched conditions and using orthogonal metho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94c82c59f98abd5913b9b5c75f259b12
https://doi.org/10.1007/s11095-021-02987-0
https://doi.org/10.1007/s11095-021-02987-0
Publikováno v:
Pharmaceutical research. 38(2)
Reversible self-association (RSA) remains a challenge in the development of therapeutic monoclonal antibodies (mAbs). We recently analyzed the energetics of RSA for five IgG mAbs (designated as A-E) under matched conditions and using orthogonal metho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::47a23da670d6024ff01f90482a18d99a
https://pubmed.ncbi.nlm.nih.gov/33604786
https://pubmed.ncbi.nlm.nih.gov/33604786
Autor:
Mandi M. Hopkins, Kathryn E. Meier
Publikováno v:
Prostaglandins, Leukotrienes and Essential Fatty Acids. 122:24-29
Many cellular actions of omega-3 fatty acids are mediated by two G protein-coupled receptors, FFA1 and FFA4, free fatty acid receptor (FFAR) family members that are activated by these dietary constituents. FFAR agonists inhibit proliferation of human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47b1cc9b0a082954cd9bb346033385ae
https://doi.org/10.1016/j.plefa.2017.06.013
https://doi.org/10.1016/j.plefa.2017.06.013
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 359:124-133
Lysophosphatidic acid (LPA) is a lipid mediator that mediates cellular effects via G protein–coupled receptors (GPCRs). Epidermal growth factor (EGF) is a peptide that acts via a receptor tyrosine kinase. LPA and EGF both induce proliferation of pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57c61857db961291b74155cd0b040492
https://doi.org/10.1124/jpet.116.233379
https://doi.org/10.1124/jpet.116.233379
Autor:
David L. Bain, Mandi M. Hopkins
Publikováno v:
The FASEB Journal. 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72aa4ced517da708dcd41ab00a731f5f
https://doi.org/10.1096/fasebj.2018.32.1_supplement.792.28
https://doi.org/10.1096/fasebj.2018.32.1_supplement.792.28
Publikováno v:
Journal of pharmaceutical sciences. 107(7)
Monoclonal antibodies (mAbs) represent a major class of biotherapeutics and are the fastest growing category of biologic drugs on the market. However, mAb development and formulation are often impeded by reversible self-association (RSA), defined as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a7a59e21e98152688696bf6edd8b7ef
https://pubmed.ncbi.nlm.nih.gov/29571738
https://pubmed.ncbi.nlm.nih.gov/29571738
Autor:
Hailey R. Bureau, Ryan Lusk, Mandi M. Hopkins, Rigoberto Hernandez, Stephen Quirk, Caley Allen, David L. Bain
Publikováno v:
ACS Omega
ACS Omega, Vol 3, Iss 2, Pp 2141-2154 (2018)
ACS Omega, Vol 3, Iss 2, Pp 2141-2154 (2018)
Neuropeptide Y (NPY) is a 36-residue peptide, abundant in the central and peripheral nervous system. The peptide interacts with membrane-bound receptors to control processes such as food intake, vasoconstriction, and memory retention. The N-terminal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaf71d4e97953f8ee24c994c345d5658
https://pubmed.ncbi.nlm.nih.gov/29619413
https://pubmed.ncbi.nlm.nih.gov/29619413
Autor:
Steven D. Blake, Mandi M. Hopkins, Xiaoxing Feng, Joy L. Hoffman, Daniel P. Powell, David W. Koh
Publikováno v:
Oncology Reports
We previously demonstrated a unique protective role for the transient receptor potential, melastatin-2 (TRPM2) cation channel in breast cancer cells. In the present study, we investigated the chemotherapeutic effects elicited by inhibiting this prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc82347be21a35002e97aeaaf1cb6cd3
https://doi.org/10.3892/or.2015.4131
https://doi.org/10.3892/or.2015.4131