Contribution of PKMζ-dependent and independent amplification to components of experimental neuropathic pain.

Autor: King T, Qu C, Okun A, Melemedjian OK, Mandell EK, Maskaykina IY, Navratilova E, Dussor GO, Ghosh S, Price TJ, Porreca F, King, Tamara, Qu, Chaoling, Okun, Alec, Melemedjian, Ohannes K, Mandell, Edward K, Maskaykina, Irina Y, Navratilova, Edita, Dussor, Gregory O, Ghosh, Sourav

Publikováno v: PAIN; Jun2012, Vol. 153 Issue 6, p1263-1273, 11p

Endosomal regulation of contact inhibition through the AMOT:YAP pathway.

Autor: Cox CM; Department of Cellular and Molecular Medicine, University of Arizona, Tucson, AZ 85724., Mandell EK; Department of Neurology, Yale University School of Medicine, New Haven, CT 06511., Stewart L; Department of Cellular and Molecular Medicine, University of Arizona, Tucson, AZ 85724., Lu R; Department of Cellular and Molecular Medicine, University of Arizona, Tucson, AZ 85724., Johnson DL; Department of Cellular and Molecular Medicine, University of Arizona, Tucson, AZ 85724., McCarter SD; Department of Cellular and Molecular Medicine, University of Arizona, Tucson, AZ 85724., Tavares A; Department of Craniofacial Biology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045., Runyan R; Department of Cellular and Molecular Medicine, University of Arizona, Tucson, AZ 85724., Ghosh S; Department of Neurology, Yale University School of Medicine, New Haven, CT 06511., Wilson JM; Department of Cellular and Molecular Medicine, University of Arizona, Tucson, AZ 85724 jeanw@email.arizona.edu.

Publikováno v: Molecular biology of the cell [Mol Biol Cell] 2015 Jul 15; Vol. 26 (14), pp. 2673-84. Date of Electronic Publication: 2015 May 20.

Targeting aPKC disables oncogenic signaling by both the EGFR and the proinflammatory cytokine TNFα in glioblastoma.

Autor: Kusne Y; Neuroscience Graduate Program, Arizona State University, Phoenix, AZ 85287, USA.; Barrow Brain Tumor Research Center, Barrow Neurological Institute, Phoenix, AZ 85013, USA., Carrera-Silva EA; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA., Perry AS; Department of Pathology, Banner MD Anderson Cancer Center, Gilbert, AZ 85234, USA., Rushing EJ; Armed Forces Institute of Pathology, Washington, DC 20306-0003, USA., Mandell EK; Department of Neurology, Yale University School of Medicine, New Haven, CT 06511, USA., Dietrich JD; Bio5OV, The University of Arizona, Oro Valley, AZ 85737, USA., Errasti AE; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA., Gibbs D; Department of Neurosciences, University of California, San Diego, San Diego, CA 92093, USA., Berens ME; Translational Genomics Research Institute (TGen), Phoenix, AZ 85004, USA., Loftus JC; Mayo Clinic Arizona, Scottsdale, AZ 85259, USA., Hulme C; Bio5OV, The University of Arizona, Oro Valley, AZ 85737, USA., Yang W; MD Anderson Cancer Center, Houston, TX 77030, USA., Lu Z; MD Anderson Cancer Center, Houston, TX 77030, USA., Aldape K; MD Anderson Cancer Center, Houston, TX 77030, USA., Sanai N; Neuroscience Graduate Program, Arizona State University, Phoenix, AZ 85287, USA.; Barrow Brain Tumor Research Center, Barrow Neurological Institute, Phoenix, AZ 85013, USA., Rothlin CV; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA., Ghosh S; Neuroscience Graduate Program, Arizona State University, Phoenix, AZ 85287, USA.; Barrow Brain Tumor Research Center, Barrow Neurological Institute, Phoenix, AZ 85013, USA.; Department of Neurology, Yale University School of Medicine, New Haven, CT 06511, USA.; Translational Genomics Research Institute (TGen), Phoenix, AZ 85004, USA.

Publikováno v: Science signaling [Sci Signal] 2014 Aug 12; Vol. 7 (338), pp. ra75. Date of Electronic Publication: 2014 Aug 12.

Competing molecular interactions of aPKC isoforms regulate neuronal polarity.

Autor: Parker SS; Department of Cellular and Molecular Medicine, University of Arizona, Tucson, AZ 85724, USA., Mandell EK, Hapak SM, Maskaykina IY, Kusne Y, Kim JY, Moy JK, St John PA, Wilson JM, Gothard KM, Price TJ, Ghosh S

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2013 Aug 27; Vol. 110 (35), pp. 14450-5. Date of Electronic Publication: 2013 Aug 12.

Dissecting protein function: an efficient protocol for identifying separation-of-function mutations that encode structurally stable proteins.

Autor: Lubin JW; Salk Institute for Biological Studies, La Jolla, California 92037-1099, USA., Rao T, Mandell EK, Wuttke DS, Lundblad V

Publikováno v: Genetics [Genetics] 2013 Mar; Vol. 193 (3), pp. 715-25. Date of Electronic Publication: 2013 Jan 10.