The proteome microenvironment determines the protective effect of preconditioning in cisplatin-induced acute kidney injury

Autor: Späth, Martin R., Bartram, Malte P., Palacio-Escat, Nicolàs, Hoyer, K. Johanna R., Debes, Cedric, Demir, Fatih, Schroeter, Christina B., Mandel, Amrei M., Grundmann, Franziska, Ciarimboli, Giuliano, Beyer, Andreas, Kizhakkedathu, Jayachandran N., Brodesser, Susanne, Göbel, Heike, Becker, Jan U., Benzing, Thomas, Schermer, Bernhard, Höhne, Martin, Burst, Volker, Saez-Rodriguez, Julio, Huesgen, Pitter F., Müller, Roman-Ulrich, Rinschen, Markus M.

Publikováno v: In Kidney International February 2019 95(2):333-349

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

The carboxy-terminus of the human ARPKD protein fibrocystin can control STAT3 signalling by regulating SRC-activation

Autor: Dafinger, Claudia, Mandel, Amrei M, Braun, Alina, Göbel, Heike, Burgmaier, Kathrin, Massella, Laura, Mastrangelo, Antonio, Dötsch, Jörg, Benzing, Thomas, Weimbs, Thomas, Schermer, Bernhard, Liebau, Max C

Publikováno v: Journal of cellular and molecular medicine, vol 24, iss 24

Autosomal recessive polycystic kidney disease (ARPKD) is mainly caused by variants in the PKHD1 gene, encoding fibrocystin (FC), a large transmembrane protein of incompletely understood cellular function. Here, we show that a C-terminal fragment of h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::04f21643e4cf423b5e1ef7fd2688cf6a
https://escholarship.org/uc/item/27d6n8td

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

The carboxy-terminus of the human ARPKD protein fibrocystin can control STAT3 signalling by regulating SRC-activation.

Autor: Dafinger C; Department of Pediatrics, University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany.; Department II of Internal Medicine, University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany.; Center for Molecular Medicine, University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany., Mandel AM; Department of Pediatrics, University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany.; Department II of Internal Medicine, University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany., Braun A; Department of Pediatrics, University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany.; Department II of Internal Medicine, University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany., Göbel H; Institute of Pathology, Faculty of Medicine, University Hospital Cologne and University of Cologne, Cologne, Germany., Burgmaier K; Department of Pediatrics, University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany., Massella L; Nephrology and Dialysis Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy., Mastrangelo A; Pediatric Nephrology, Dialysis and Transplant Unit, Fondazione IRCCS Cà Granda, Ospedale Maggiore Policlinico, Milan, Italy., Dötsch J; Department of Pediatrics, University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany., Benzing T; Department II of Internal Medicine, University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany.; Center for Molecular Medicine, University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany.; CECAD, University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany.; Systems Biology of Ageing Cologne, University of Cologne, Cologne, Germany., Weimbs T; Molecular, Cellular, and Developmental Biology, and Neuroscience Research Institute, University of California, Santa Barbara, CA, USA., Schermer B; Department II of Internal Medicine, University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany.; Center for Molecular Medicine, University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany.; CECAD, University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany.; Systems Biology of Ageing Cologne, University of Cologne, Cologne, Germany., Liebau MC; Department of Pediatrics, University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany.; Department II of Internal Medicine, University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany.; Center for Molecular Medicine, University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany.

Publikováno v: Journal of cellular and molecular medicine [J Cell Mol Med] 2020 Dec; Vol. 24 (24), pp. 14633-14638. Date of Electronic Publication: 2020 Oct 28.