Výsledky vyhledávání - "Mandeep Marwah"

Akademický článek

Exploring mitochondrial hydrogen sulfide signalling for therapeutic interventions in vascular diseases

Autor: Lorena Diaz Sanchez, Lissette Sanchez-Aranguren, Mandeep Marwah, Keqing Wang, Corinne M Spickett, Helen R Griffiths, Irundika HK Dias

Publikováno v: Advances in Redox Research, Vol 4, Iss , Pp 100030- (2022)

Hydrogen sulfide (H2S), a gaseous signalling molecule, is important in numerous physiological and pathophysiological processes. Despite its initial identification as an environmental toxin, H2S is now well described as an essential physiological mole

Externí odkaz: https://doaj.org/article/611ade58d25a488f89c5e4e0e2f83420

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Hydrogen Sulphide-Based Therapeutics for Neurological Conditions: Perspectives and Challenges

Autor: Amir H. Sharif, Mohammed Iqbal, Bahareh Manhoosh, Negin Gholampoor, Dan Ma, Mandeep Marwah, Lissette Sanchez-Aranguren

Publikováno v: Neurochemical Research. 48:1981-1996

Central nervous system (CNS)-related conditions are currently the leading cause of disability worldwide, posing a significant burden to health systems, individuals and their families. Although the molecular mechanisms implicated in these disorders ma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9c86d4a551eaee352234d4a63d13e133
https://doi.org/10.1007/s11064-023-03887-y

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Transdermal Delivery of a Hydrogen Sulphide Donor, ADT-OH Using Aqueous Gel Formulations for the Treatment of Impaired Vascular Function:an Ex Vivo Study

Autor: Mandeep Marwah, Hala Shokr, Lissette Sanchez-Aranguren, Shakil Ahmad, Raj Badhan, Keqing Wang

Publikováno v: Marwah, M K, Shokr, H, Sanchez-Aranguren, L, Badhan, R K S, Wang, K & Ahmad, S 2022, ' Transdermal Delivery of a Hydrogen Sulphide Donor, ADT-OH Using Aqueous Gel Formulations for the Treatment of Impaired Vascular Function : an Ex Vivo Study ', Pharmaceutical Research, vol. 39, no. 2, pp. 341-352 . https://doi.org/10.1007/s11095-021-03164-z

Purpose Hydrogen sulphide (H2S) is an important signalling molecule involved in the regulation of several physiological and pathophysiological processes. The objective of this study was to investigate the feasibility of transdermal delivery of ADT-OH

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18579ddcfb98e9269edf2d5f93395c27
https://doi.org/10.1007/s11095-021-03164-z

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Neuroprotective effects of mitochondrial-targeted hydrogen sulphide donor, AP39 on H2O2-induced oxidative stress in human neuroblastoma SHSY5Y cell line

Autor: Lissette Sanchez-Aranguren, Mandeep Marwah, Sarah Nadeem

Publikováno v: Advances in Redox Research, Vol 3, Iss, Pp 100024-(2021)

Oxidative stress (OS) resulting from imbalance in the generation of reactive oxygen species (ROS) and/or the dysfunction of the antioxidant machinery, is a key mechanism associated with the onset of neurodegenerative disorders. Although the molecular

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44ede64cd868aef1f55dd92e6ecf366c
http://www.sciencedirect.com/science/article/pii/S2667137921000242

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Analysis of laboratory blood parameter results for patients diagnosed with COVID‐19, from all ethnic group populations: A single centre study

Autor: Farooq Wandroo, Patrick Ball, Sukhjinder Marwah, Mandeep Marwah, Hana Morrissey, Andrew Blann

Publikováno v: International Journal of Laboratory Hematology

Introduction Although factors such as age, sex, diabetes, obesity and changes in certain laboratory investigations are important prognostic factors in COVID‐19 infection, these may not apply to all ethnic/racial groups. We hypothesized differences

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4775b31481fe3cd4c2cf1f4d5414a39
https://publications.aston.ac.uk/id/eprint/42566/1/ijlh.13538.pdf

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Development of a novel polymer-based carrier for deformable liposomes for the controlled dermal delivery of naringenin

Autor: Mandeep Marwah, Raj K.S. Badhan, Deborah Lowry

Publikováno v: Journal of liposome research. 32(2)

In recent years, the incidence of skin cancer has increased worldwide, presenting a significant burden on healthcare services. Chemotherapy intervention is often not appropriate for all patients due to localized adverse effects on skin physiology. Th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c81b3dc2ee96b884bc517019530804cc
https://pubmed.ncbi.nlm.nih.gov/34423727

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Intracellular uptake of EGCG-loaded deformable controlled release liposomes for skin cancer

Autor: Deborah Lowry, Raj K.S. Badhan, Mandeep Marwah, Yvonne Perrie

Caucasian population groups have a higher propensity to develop skin cancer, and associated clinical interventions often present substantial financial burden on healthcare services. Conventional treatments are often not suitable for all patient group

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0863f73165ab81aaef2d43d61995e53
https://strathprints.strath.ac.uk/68362/1/Marwah_etal_JLR_2019_Intracellular_uptake_of_EGCG_loaded_deformable_controlled.pdf

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