Two isoleucyl tRNAs that decode synonymous codons divergently regulate breast cancer metastatic growth by controlling translation of proliferation-regulating genes

Autor: Lisa B. Earnest-Noble, Dennis Hsu, Siyu Chen, Hosseinali Asgharian, Mandayam Nandan, Maria C. Passarelli, Hani Goodarzi, Sohail F. Tavazoie

Publikováno v: Nature Cancer. 3:1484-1497

The human genome contains 61 codons encoding 20 amino acids. Synonymous codons representing a given amino acid are decoded by a set of transfer RNAs (tRNAs) called isoacceptors. We report the surprising observation that two isoacceptor tRNAs that dec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::180b622ed9ef809da49320925f06e478
https://doi.org/10.1038/s43018-022-00469-9

Hyundai Deepens India Bet, Files For IPO That Could Be Country’s Biggest.

Autor: N. R., SETHURAMAN, MANDAYAM, NANDAN, SHAH, ADITI

Publikováno v: News India Times. 6/28/2024, Vol. 55 Issue 26, p10-10. 1/3p.

Arginine limitation causes a directed DNA sequence evolution response in colorectal cancer cells.

Autor: Hsu DJ; Laboratory of Systems Cancer Biology, The Rockefeller University, New York, NY, USA.; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Gao J; Laboratory of Systems Cancer Biology, The Rockefeller University, New York, NY, USA., Yamaguchi N; Laboratory of Systems Cancer Biology, The Rockefeller University, New York, NY, USA., Pinzaru A; Laboratory of Systems Cancer Biology, The Rockefeller University, New York, NY, USA., Mandayam N; Laboratory of Systems Cancer Biology, The Rockefeller University, New York, NY, USA., Liberti M; Laboratory of Systems Cancer Biology, The Rockefeller University, New York, NY, USA., Heissel S; Proteomics Resource Center, The Rockefeller University, New York, NY, USA., Alwaseem H; Proteomics Resource Center, The Rockefeller University, New York, NY, USA., Tavazoie S; Department of Systems Biology, Columbia University Medical Center, New York, NY, USA.; Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY USA., Tavazoie SF; Laboratory of Systems Cancer Biology, The Rockefeller University, New York, NY, USA.; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Jan 02. Date of Electronic Publication: 2023 Jan 02.