Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Mandakh Bekhbat"'
Autor:
Mandakh Bekhbat
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 40, Iss , Pp 100843- (2024)
Inflammation is one biological pathway thought to impact the brain to contribute to major depressive disorder (MDD) and is reliably associated with resistance to standard antidepressant treatments. While peripheral immune cells, particularly monocyte
Externí odkaz:
https://doaj.org/article/b0c92bc65d5f4e16b11db8dde85d5154
Autor:
Sydney Rowson, Mandakh Bekhbat, Sean Kelly, Molly M. Hyer, Samya Dyer, David Weinshenker, Gretchen Neigh
Publikováno v:
Stress, Vol 27, Iss 1 (2024)
AbstractChronic stress exposure during development can have lasting behavioral consequences that differ in males and females. More specifically, increased depressive behaviors in females, but not males, are observed in both humans and rodent models o
Externí odkaz:
https://doaj.org/article/2c6c0a3909b0480e81ed8769067efb7e
Autor:
Mandakh Bekhbat, John Drake, Emily C. Reed, Tatlock H. Lauten, Tamara Natour, Vladimir I. Vladimirov, Adam J. Case
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 34, Iss , Pp 100690- (2023)
Psychosocial stress has been shown to prime peripheral innate immune cells, which take on hyper-inflammatory phenotypes and are implicated in depressive-like behavior in mouse models. However, the impact of stress on cellular metabolic states that ar
Externí odkaz:
https://doaj.org/article/855272ad0ca741118e6630d5dbdc1818
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 26, Iss , Pp 100569- (2022)
Clinical depression and anxiety are not just national health issues. They are significant global health problems, with a worldwide prevalence of clinical depression amounting to nearly 4%. Moreover, its prevalence is certainly underreported, particul
Externí odkaz:
https://doaj.org/article/a9254d42e68a43aa9cbb476059066fca
Publikováno v:
Neurobiology of Stress, Vol 19, Iss , Pp 100462- (2022)
Inflammation is associated with symptoms of anhedonia, a core feature of major depression (MD). We have shown that MD patients with high inflammation as measured by plasma C-reactive protein (CRP) and anhedonia display gene signatures of metabolic re
Externí odkaz:
https://doaj.org/article/f28c189a8a194af1b68bbbfd9de43f4f
Publikováno v:
Biological Psychiatry. 93:405-418
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62e60b48e1d09e3cb7fd33fe48f5a6d4
https://doi.org/10.1016/j.biopsych.2022.11.003
https://doi.org/10.1016/j.biopsych.2022.11.003
Autor:
Jaehoon Kim, Taehee Yoon, Paul Kim, Mandakh Bekhbat, So Mang Kang, Hoon Suk Rho, Song Ih Ahn, YongTae Kim
Publikováno v:
Lab on a Chip.
A micro-engineered physiological system-tissue barrier chip (MEPS-TBC) has been developed as a highly replicable model of the human blood–brain barrier (BBB) with a 3D perivascular space using tunable aspiration technique.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::977637501bb2037e8eae46045f6a883a
https://doi.org/10.1039/d3lc00124e
https://doi.org/10.1039/d3lc00124e
Autor:
Jennifer C. Felger, Bobbi J. Woolwine, David R. Goldsmith, Ebrahim Haroon, Mandakh Bekhbat, Andrew H. Miller
Publikováno v:
Molecular Psychiatry. 26:7384-7392
Inflammation impacts basal ganglia motor circuitry in association with psychomotor retardation, a key symptom of major depression (MD). We previously reported associations between circulating protein inflammatory biomarkers and psychomotor slowing as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5322f936afb11dcce098c8587ff7f2a9
https://doi.org/10.1038/s41380-021-01258-z
https://doi.org/10.1038/s41380-021-01258-z
Autor:
Leah H. Rubin, Mandakh Bekhbat, Susie Turkson, C. Christina Mehta, Pauline M. Maki, Kathryn Anastos, Deborah Gustafson, Amanda B. Spence, Joel Milam, Felicia C. Chow, Kathleen Weber, Gayle Springer, Stephen J. Gange, Gretchen N. Neigh
Publikováno v:
Psychosomatic medicine. 84(8)
Alterations in glucocorticoid receptor (GCR) function may be a risk factor for cognitive complications among older people with human immunodeficiency virus (HIV). We evaluated whether HIV serostatus and age modify the GCR function-cognition associati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3a33e59ce06058bb9e49371fafa6439
https://pubmed.ncbi.nlm.nih.gov/36044614
https://pubmed.ncbi.nlm.nih.gov/36044614
Autor:
Molly M. Hyer, Zhaohui S. Qin, Gregory K. Tharp, Mandakh Bekhbat, Mikhail G. Dozmorov, Gretchen N. Neigh, Deepika Mukhara, Sydney A. Rowson, Savannah D. Benusa, Sean D. Kelly, John C Stansfield, Malú G. Tansey, Jeffrey L. Dupree
Publikováno v:
Neuropsychopharmacology
Adolescent exposure to chronic stress, a risk factor for mood disorders in adulthood, sensitizes the neuroinflammatory response to a subsequent immune challenge. We previously showed that chronic adolescent stress (CAS) in rats led to distinct patter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea7800d41b8566b8f2729dac3ff98c82
https://doi.org/10.1038/s41386-021-00970-2
https://doi.org/10.1038/s41386-021-00970-2