Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Manda Wong"'
Autor:
Wen-Ting K. Tsai, Yinyin Li, Zhaojun Yin, Peter Tran, Qui Phung, Zhenru Zhou, Kun Peng, Dan Qin, Sien Tam, Christoph Spiess, Jochen Brumm, Manda Wong, Zhengmao Ye, Patrick Wu, Sivan Cohen, Paul J. Carter
Publikováno v:
mAbs, Vol 16, Iss 1 (2024)
Bispecific antibodies, including bispecific IgG, are emerging as an important new class of antibody therapeutics. As a result, we, as well as others, have developed engineering strategies designed to facilitate the efficient production of bispecific
Externí odkaz:
https://doaj.org/article/9805ef0547804dc680ba4370dfa5869f
Autor:
Elaine Mai, Joyce Chan, Levina Goon, Braeden K. Ego, Jack Bevers, Tiffany Wong, Manda Wong, Racquel Corpuz, Hongkang Xi, Jia Wu, Kellen Schneider, Dhaya Seshasayee, Michele Grimbaldeston, Gerald Nakamura, Vahan B. Indjeian, Menno van Lookeren Campagne, Kelly M. Loyet, Laetitia Comps-Agrar
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-15 (2021)
Abstract Background Over the past decade, human Interleukin 33 (hIL-33) has emerged as a key contributor to the pathogenesis of numerous inflammatory diseases. Despite the existence of several commercial hIL-33 assays spanning multiple platform techn
Externí odkaz:
https://doaj.org/article/bbbe6e02b17b49a79ce3aff20db379de
Autor:
Rachel Melendez, Benjamin Ordonia, Joyce Guerrero, Azadeh Hassanzadeh, Peter Tran, Justin Low, Manda Wong, Jochen Brumm, Shan Chung, Lynn Kamen
Publikováno v:
Bioanalysis. 14:703-713
Aim: Immunogenicity risk assessment assays are powerful tools that assess the relative immunogenicity of potential biotherapeutics. We detail here the development of a novel assay that measures the degree of antibody internalization by antigen-presen
Autor:
Siddharth Sukumaran, Elsa-Noah N’Diaye, Alexander R. Abbas, Wei-Ching Liang, Katrina B. Morshead, Hans Brightbill, Meron Roose-Girma, Daryle Depianto, Claire Emson, Zhiyu Huang, Jean-Michel Vernes, Jianping Yin, Paul J. Wolters, Tiffany Wong, Hua Zhang, Y. Gloria Meng, Manda Wong, Nico Ghilardi, Zora Modrusan, Patrick Caplazi, Dhaya Seshasayee, Min Xu, Surinder Jeet, Tianhe Sun, Yan Wu, Kai-Hui Sun, Jia Wu, Thirumalai R. Ramalingam, Joseph R. Arron, Jeff Lutman, Wei Yu Lin, Rajbharan Yadav, Racquel Corpuz, Patrick J. Lupardus, Jason A. Vander Heiden
Publikováno v:
Science translational medicine, vol 13, iss 605
Transforming growth factor-β (TGFβ) is a key driver of fibrogenesis. Three TGFβ isoforms (TGFβ1, TGFβ2, and TGFβ3) in mammals have distinct functions in embryonic development; however, the postnatal pathological roles and activation mechanisms
Autor:
Kelly M. Loyet, Neil N. Trivedi, Racquel Corpuz, Brian L. Yaspan, Tracy Staton, Henry R. Maun, Erin H. Christensen, Kathila R. Alatsis, Xiumin Wu, Michael T. Lipari, Yvonne Franke, Mark S. Dennis, Daniel Kirchhofer, Wyne P. Lee, Rahul Ahuja, Xiaocheng Chen, Ashley Morando, Diana Chang, James T. Koerber, Aija Kusi, Joseph R. Arron, John Liu, Guiquan Jia, Juan Zhang, Janet Jackman, Ping Wu, George H. Caughey, Yan Wu, Rajesh Vij, Luz D. Orozco, Lawrence B. Schwartz, Benjamin T. Walters, Charles Eigenbrot, Prescott G. Woodruff, Lawren C. Wu, David F. Choy, Robert A. Lazarus, Meire Bremer, Amy Dressen, Magda Babina, Tangsheng Yi, Savita Ubhayakar, Xiaorong Liang, Jeff Lutman, Siddharth Sukumaran, Jason A. Hackney, John V. Fahy, Julie Q. Hang, Cary D. Austin, Manda Wong
Publikováno v:
Cell, vol 179, iss 2
Cell
Cell
Severe asthma patients with low type 2 inflammation derive less clinical benefit from therapies targeting type 2 cytokines and have significant unmet medical needs. We show that mast cell tryptase is elevated in severe asthma patients, correlating wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8c0946c02d2066eb05676694e454e0e
https://escholarship.org/uc/item/8pf5p52n
https://escholarship.org/uc/item/8pf5p52n
Autor:
Gerald R. Nakamura, Manda Wong, Xinhua Wang, Nan Chiang, Alberto Estavez, Claudio Ciferri, Mary Mathieu, Tao Huang, Randall J. Brezski, Sophia Lee, Jack Bevers, Yee Seir Kee
Anti-hinge antibodies (AHAs) are an autoantibody subclass that, following proteolytic cleavage, recognize cryptic epitopes exposed in the hinge regions of immunoglobulins (Igs) and do not bind to the intact Ig counterpart. AHAs have been postulated t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a72e3f568e2cebc2a7bcb40cdd0747d9
https://europepmc.org/articles/PMC5777262/
https://europepmc.org/articles/PMC5777262/