Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Manda Orgeron"'
Autor:
Kirsten P. Stone, Sujoy Ghosh, Jean Paul Kovalik, Manda Orgeron, Desiree Wanders, Landon C. Sims, Thomas W. Gettys
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract The initial sensing of dietary methionine restriction (MR) occurs in the liver where it activates an integrated stress response (ISR) that quickly reduces methionine utilization. The ISR program is regulated in part by ATF4, but ATF4’s pro
Externí odkaz:
https://doaj.org/article/47e11d4a223a47389d7444778bbfe088
Autor:
Manda Orgeron, Kirsten P. Stone, Landon C. Sims, Sujoy Ghosh, Thomas W. Gettys, Jean-Paul Kovalik, Desiree Wanders
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
The initial sensing of dietary methionine restriction (MR) occurs in the liver where it activates an integrated stress response (ISR) that quickly reduces methionine utilization. The ISR program is regulated in part by ATF4, but ATF4’s prototypical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::579f19931e85a8251c1bfa78ad7e426e
https://doi.org/10.1038/s41598-021-83380-0
https://doi.org/10.1038/s41598-021-83380-0
Publikováno v:
Diabetes
To understand the physiological significance of the reduction in fasting insulin produced by dietary methionine restriction (MR), hyperinsulinemic-euglycemic clamps were used to examine the effect of the diet on overall and tissue-specific insulin se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a7df63e073e278c768c01967f087316
https://doi.org/10.2337/db14-0464
https://doi.org/10.2337/db14-0464
Autor:
Thomas W. Gettys, Desiree Wanders, Nancy T. Van, Manda Orgeron, Cory C. Cortez, Kirsten P. Stone
Calorie restriction without malnutrition, commonly referred to as dietary restriction (DR), results in a well-documented extension of life span. DR also produces significant, long-lasting improvements in biomarkers of metabolic health that begin to a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bea700f6d4d535deb81f747d5e3df29
https://doi.org/10.1016/b978-0-12-800101-1.00011-9
https://doi.org/10.1016/b978-0-12-800101-1.00011-9
Autor:
Alexandra N McDaniel, Eric P. Plaisance, Nancy T. Van, Thomas W. Gettys, Tracy G. Anthony, Manda Orgeron, Phillip H Behrens
Publikováno v:
The FASEB Journal. 26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::250f24dbc46bd8329d2835a1a3adfe64
https://doi.org/10.1096/fasebj.26.1_supplement.255.1
https://doi.org/10.1096/fasebj.26.1_supplement.255.1