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P53 Activation Promotes Maturational Characteristics of Pluripotent Stem Cell-Derived Cardiomyocytes in 3-Dimensional Suspension Culture Via FOXO-FOXM1 Regulation.

Autor: Velayutham N; Department of Stem Cell and Regenerative Biology and the Harvard Stem Cell Institute Harvard University Cambridge MA USA., Garbern JC; Department of Stem Cell and Regenerative Biology and the Harvard Stem Cell Institute Harvard University Cambridge MA USA.; Department of Cardiology Boston Children's Hospital Boston MA USA., Elwell HLT; Department of Stem Cell and Regenerative Biology and the Harvard Stem Cell Institute Harvard University Cambridge MA USA., Zhuo Z; Bioinformatics Core, Department of Biostatistics Harvard T.H. Chan School of Public Health Boston MA USA., Rüland L; Department of Stem Cell and Regenerative Biology and the Harvard Stem Cell Institute Harvard University Cambridge MA USA., Elcure Alvarez F; Department of Stem Cell and Regenerative Biology and the Harvard Stem Cell Institute Harvard University Cambridge MA USA., Frontini S; Department of Stem Cell and Regenerative Biology and the Harvard Stem Cell Institute Harvard University Cambridge MA USA., Rodriguez Carreras Y; Department of Stem Cell and Regenerative Biology and the Harvard Stem Cell Institute Harvard University Cambridge MA USA., Eichholtz M; Department of Stem Cell and Regenerative Biology and the Harvard Stem Cell Institute Harvard University Cambridge MA USA., Ricci-Blair E; Department of Stem Cell and Regenerative Biology and the Harvard Stem Cell Institute Harvard University Cambridge MA USA., Shaw JY; Department of Stem Cell and Regenerative Biology and the Harvard Stem Cell Institute Harvard University Cambridge MA USA., Bouffard AH; Department of Stem Cell and Regenerative Biology and the Harvard Stem Cell Institute Harvard University Cambridge MA USA., Sokol M; Department of Stem Cell and Regenerative Biology and the Harvard Stem Cell Institute Harvard University Cambridge MA USA., Mancheño Juncosa E; Department of Stem Cell and Regenerative Biology and the Harvard Stem Cell Institute Harvard University Cambridge MA USA., Rhoades S; Ginkgo Bioworks Boston MA USA., van den Berg D; Department of Stem Cell and Regenerative Biology and the Harvard Stem Cell Institute Harvard University Cambridge MA USA., Kreymerman A; Department of Stem Cell and Regenerative Biology and the Harvard Stem Cell Institute Harvard University Cambridge MA USA., Aoyama J; Department of Stem Cell and Regenerative Biology and the Harvard Stem Cell Institute Harvard University Cambridge MA USA., Höfflin J; Ginkgo Bioworks Boston MA USA., Ryan H; Ginkgo Bioworks Boston MA USA., Ho Sui S; Bioinformatics Core, Department of Biostatistics Harvard T.H. Chan School of Public Health Boston MA USA., Lee RT; Department of Stem Cell and Regenerative Biology and the Harvard Stem Cell Institute Harvard University Cambridge MA USA.; Division of Cardiovascular Medicine, Department of Medicine Brigham and Women's Hospital and Harvard Medical School Boston MA USA.

Publikováno v: Journal of the American Heart Association [J Am Heart Assoc] 2024 Jul 02; Vol. 13 (13), pp. e033155. Date of Electronic Publication: 2024 Jun 27.