Výsledky vyhledávání - "Manchand, A."

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IJSRSET173292 | Assessment of Effectiveness, Plan and Design of Watershed Management: A Case Study of Khor Village, Daund Tehsil, Pune District, Maharashtra, India

Autor: Manchand Singh, Kulkarni, Deepali, S D Talegoankar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b757151ce35785a86c113870b56eb616

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Carbon-14 labeling of Saxagliptin (BMS-477118)

Autor: Kai Cao, Balu Balasubramanian, Ramaswamy A. Iyer, Ronald L. Hanson, Hong Su, Manchand Percy Sarwood, Samuel J. Bonacorsi, Jollie D. Godfrey, Rita Fox, Lisa J. Christopher

Publikováno v: Journal of Labelled Compounds and Radiopharmaceuticals. 50:1224-1229

An efficient synthesis of carbon-14-labeled Saxagliptin (BMS-477118) is described. Initial synthesis of the key radiolabeled intermediate (S)-N-Boc-2-(3′-hydroxyadamantyl)glycine 2a utilized adamantanemethanol in a 10-step sequence. To shorten the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c4f375ca19f8c37120f857d401257213
https://doi.org/10.1002/jlcr.1450

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1α,25-Dihydroxy-16-ene-23-yne-vitamin D3 and 1α,25-Dihydroxy-16-ene-23-yne-20-epi-vitaminD3: Analogs of 1α,25-Dihydroxyvitamin D3 That Resist Metabolism through the C-24 Oxidation Pathway Are Metabolized through the C-3 Epimerization Pathway

Autor: Norbert Astecker, D.Sunita Rao, Paul Vouros, Gino J. Sasso, Mei-Ling Siu-Caldera, Milan R. Uskokovic, Percy S. Manchand, A. Weiskopf, G. Satyanarayana Reddy

Publikováno v: Archives of Biochemistry and Biophysics. 383:197-205

The secosteroid hormone 1alpha,25-dihydroxyvitamin D3 [1alpha,25(OH)2D3] is metabolized in its target tissues through modifications of both the side chain and the A-ring. The C-24 oxidation pathway, the previously well established main side chain mod

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2bfdcedb4c00fee8f2da4814bc38c4b
https://doi.org/10.1006/abbi.2000.2074

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Characterization of a Novel Analogue of 1α,25(OH)2-Vitamin D3 with Two Side Chains: Interaction with Its Nuclear Receptor and Cellular Actions

Autor: H. P. Koeffler, Anthony W. Norman, Manchand Ps, Sara Peleg, J. E. Bishop, Takeuchi Ja, Uskokovic Mr, W. H. Okamura, Hisatake Ji

Publikováno v: Journal of Medicinal Chemistry. 43:2719-2730

The hormone 1alpha,25(OH)(2)-vitamin D(3) (125D) binds to its nuclear receptor (VDR) to stimulate gene transcription activity. Inversion of configuration at C-20 of the side chain to generate 20-epi-1alpha,25(OH)(2)D(3) (20E-125D) increases transcrip

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9131444b16e49c345d757755680c91af
https://doi.org/10.1021/jm0000160

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Effects of curcumin, demethoxycurcumin, bisdemethoxycurcumin and tetrahydrocurcumin on 12-O-tetradecanoylphorbol-13-acetateinduced tumor promotion

Autor: Harold L. Newmark, Wei Ma, Mou-Tuan Huang, P. S. Manchand, Allan H. Conney, C. Fisher, Richard L. Chang, Yao-Ping Lu

Publikováno v: Carcinogenesis. 16:2493-2497

Commercial grade curcumin (approximately 77% curcumin, 17% demethoxycurcumin and 3% bisdemethoxycurcumin) is widely used as a yellow coloring agent and spice in foods. In the present study topical application of commercial grade curcumin, pure curcum

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc6f8f851295d4a3ae805307b1f33260
https://doi.org/10.1093/carcin/16.10.2493

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Oral health status and treatment needs among health-care workers in Shimla district, Himachal Pradesh India

Autor: Kavita Manchand, Vikas Fotedar, Shailee Fotedar, Vinay Kumar Bhardwaj, Shelja Vashisht

Publikováno v: Indian Journal of Oral Health and Research. 2:82

Objectives: To assess oral health status and treatment needs of the health workers in Shimla district, Himachal Pradesh. Materials and Methods: A cross-sectional study was conducted among health workers in Shimla district, Himachal Pradesh. A sample

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b573e0cfbaa4f1e90358364c95adffdd
https://doi.org/10.4103/2393-8692.196113

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A Practical Synthesis of l-Valyl-pyrrolidine-(2R)-boronic Acid: Efficient Recycling of the Costly Chiral Auxiliary (+)-Pinanediol

Autor: David R. Kronenthal, Maxime Soumeillant, Frank Gibson, Michael J. Humora, Manchand Percy Sarwood, Ambarish K. Singh

Publikováno v: Organic Process Research & Development. 6:814-816

A practical synthesis of l-valyl-pyrrolidine-(2R)-boronic acid (1) is detailed. A previously disclosed synthesis of 1 (Snow, R.; Kelly, T. R.; Adams, J.; Coutts, S.; Perry, C. (Boehringer Ingelheim Pharmaceuticals, Inc.). WO 93/10127, 1993) was signi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::daec2688701538dd76f16ea19137a675
https://doi.org/10.1021/op025587b

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Synthesis of a biologically active vitamin D2 metabolite

Autor: Percy S. Manchand, David L. Coffen, Lucia Serico, Satish C. Choudhry, Peter S. Belica, Antonino Focella, Hubert Maehr, Roxana Yang

Publikováno v: The Journal of Organic Chemistry. 58:1496-1500

The synthesis of 1α,25,28-trihydroxyvitamin-D 2 (1) from vitamin-D 2 is described. The synthesis involves three key features:() the dissection of the vitamin-D2 side chain, (ii) C-1 hydroxylation, and (iii) the preparation and introduction of the ap

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bb35707854ff59825a4449ab0fc15549
https://doi.org/10.1021/jo00058a034

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