Zobrazeno 1 - 10
of 118
pro vyhledávání: '"Mancang, Gu"'
Autor:
Dong Wang, Wenzhe Chen, Jiali Chen, Du He, Yanli Pan, Pinger Wang, Qinghe Zeng, Mancang Gu, Peijian Tong, Di Chen, Hongting Jin
Publikováno v:
Bioactive Materials, Vol 40, Iss , Pp 47-63 (2024)
In individuals afflicted with hemophilia, characterized by a deficiency of coagulation factor VIII (FVIII), the occurrence of spontaneous recurrent intra-articular hemorrhage precipitates the emergence of hemophilic arthropathy (HA). Although clottin
Externí odkaz:
https://doaj.org/article/0044da476f984a10934c93726ec4836b
Publikováno v:
Clinical and Translational Discovery, Vol 4, Iss 3, Pp n/a-n/a (2024)
Externí odkaz:
https://doaj.org/article/b5e47f535b494972a0208b6315761c24
Publikováno v:
Clinical and Translational Medicine, Vol 13, Iss 12, Pp n/a-n/a (2023)
Abstract Background Inhibition of CDK7, a potent transcription regulator, may bring new hope for treating pancreatic ductal adenocarcinoma (PDAC), which is featured by large genetic heterogeneity and abundant KRAS mutations. This investigation aimed
Externí odkaz:
https://doaj.org/article/e3cba189f2074e65a878f9ee0abd45c8
Autor:
Huijuan Chen, Anzhi Hu, Mengdi Xiao, Shiyi Hong, Jing Liang, Quanlong Zhang, Yang Xiong, Mancang Gu, Chaofeng Mu
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 18, Iss 6, Pp 100868- (2023)
Several crucial stromal cell populations regulate hematopoiesis and malignant diseases in bone marrow niches. Precise regulation of these cell types can remodel niches and develop new therapeutics. Multiple nanocarriers have been developed to transpo
Externí odkaz:
https://doaj.org/article/ab5a714e98bb483c80d0d28d3675a58f
Autor:
Hongyan Zhang, Liying Chen, Yue Zhao, Ningchao Luo, Jingbin Shi, Shujun Xu, Lisha Ma, Menglin Wang, Mancang Gu, Chaofeng Mu, Yang Xiong
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 18, Iss 2, Pp 100796- (2023)
Cancer-associated fibroblasts (CAFs) are one of the most abundant stromal cells in the tumor microenvironment which mediate desmoplastic response and are the primary driver for an immunosuppressive microenvironment, leading to the failure of triple-n
Externí odkaz:
https://doaj.org/article/01a98a43e3fb4605a036894d7d7a9eee
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 1, Pp 364-377 (2022)
Up to 70% of patients with late-stage breast cancer have bone metastasis. Current treatment regimens for breast cancer bone metastasis are palliative with no therapeutic cure. Disseminated tumor cells (DTCs) colonize inside the osteogenic niches in t
Externí odkaz:
https://doaj.org/article/644caeecf09544baa9e7f00629704a4f
Autor:
Qinghe Zeng, Rui Xu, Houfu Ling, Shan Zhao, Xu Wang, Wenhua Yuan, Mancang Gu, Taotao Xu, Pinger Wang, Hongfeng Ruan, Hongting Jin, Hangbo Qu, Fusheng Ye, Jiali Chen
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Postmenopausal Osteoporosis (PMOP) is the most prevalent primary osteoporosis, attributable to an imbalance in osteoblast and osteoclast activity. Modified You-Gui-Yin (MYGY), a traditional Chinese herbal formula, is able to effectively treat PMOP, w
Externí odkaz:
https://doaj.org/article/aad52abee5d44ecabd4a4a45d053f72f
Autor:
Rui Xu, Qinghe Zeng, Chenjie Xia, Jiali Chen, Pinger Wang, Shan Zhao, Wenhua Yuan, Zhaohuan Lou, Houfu Lin, Hanting Xia, Shuaijie Lv, Taotao Xu, Peijian Tong, Mancang Gu, Hongting Jin
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Background: Shen-sui-tong-zhi formula (SSTZF) has been used to treat osteoporosis for decades and shows excellent clinical efficacy. This article aims to explore the optimal anti-osteoporotic ingredient and its precise mechanisms in mice models.Metho
Externí odkaz:
https://doaj.org/article/157d8c5d55414c6c935cccde3ac3d50d
Autor:
Qin, Yansong1 (AUTHOR), Gu, Mancang2,3 (AUTHOR) gmancang@zcmu.edu.cn, Shi, Yan4 (AUTHOR) sy_rjh@aliyun.com, Huang, Lei5,6 (AUTHOR) lei.huang@alumni.dkfz.de
Publikováno v:
Clinical & Translational Discovery. Jun2024, Vol. 4 Issue 3, p1-3. 3p.
Publikováno v:
Journal of Bionic Engineering. 20:711-721