Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Manbok Kim"'
Publikováno v:
PLoS Pathogens, Vol 5, Iss 10, p e1000635 (2009)
NF-kappaB and inflammasomes both play central roles in orchestrating anti-pathogen responses by rapidly inducing a variety of early-response cytokines and chemokines following infection. Myxoma virus (MYXV), a pathogenic poxvirus of rabbits, encodes
Externí odkaz:
https://doaj.org/article/d1081f0763534315b0dafca6670937bb
Publikováno v:
The KSFM Journal of Fluid Machinery. 25:43-49
Autor:
Manbok Kim
Publikováno v:
BMB Reports
Naturally occurring reoviruses are live replication-proficient viruses that specifically infect human cancer cells while sparing their normal counterpart. Since the discovery of reoviruses in 1950s, they have shown various degrees of safety and effic
Publikováno v:
Biochemical and Biophysical Research Communications. 462:283-287
Epstein-Barr virus (EBV) has been associated with a variety of epithelial and hematologic malignancies, including B-, T- and NK cell-lymphomas, Hodgkin's disease (HD), post-transplant lymphoproliferative diseases (LPDs), nasopharyngeal and gastric ca
Autor:
Jeong-Soo Park, Manbok Kim
Publikováno v:
Journal of microbiology (Seoul, Korea). 55(1)
Naturally occurring reoviruses are live replication-proficient viruses specifically infecting human cancer cells while sparing the normal counterparts. Stem cells can be highly susceptible to viral infection due to their innate high proliferation pot
Autor:
Masmudur M. Rahman, Amy Meacham, Christopher R. Cogle, Edward W. Scott, Grant McFadden, Eric Bartee, Manbok Kim, Gerard J. Madlambayan
Publikováno v:
Leukemia Research. 36:619-624
Some oncolytic viruses, such as myxoma virus (MYXV), can selectively target malignant hematopoietic cells, while sparing normal hematopoietic cells. This capacity for discrimination creates an opportunity to use oncolytic viruses as ex vivo purging a
Autor:
Stefan J. Urbanski, Katy A. Garant, S D Loken, Derrick E. Rancourt, Patrick W. K. Lee, Manbok Kim, Peter A. Forsyth, Randal N. Johnston, Tommy Alain, N.I. zur Nieden
Publikováno v:
British journal of cancer, vol 104, iss 2
British Journal of Cancer
British Journal of Cancer
Background: Although the naturally occurring reovirus causes only mild symptoms in humans, it shows considerable potential as an oncolytic agent because of its innate ability to target cancer cells. In immunocompromised hosts, however, wild-type reov
Autor:
Sherin Smallwood, Amy Meacham, Masmudur M. Rahman, Koji Hosaka, Edward W. Scott, Grant McFadden, Gerard J. Madlambayan, Manbok Kim, Christopher R. Cogle
Publikováno v:
Leukemia
Myxoma virus targets primary human leukemic stem and progenitor cells while sparing normal hematopoietic stem and progenitor cells
Autor:
Cay Egan, Patrick W. K. Lee, Peter A. Forsyth, Stefan J. Urbanski, Tommy Alain, Manbok Kim, Randal N. Johnston
Publikováno v:
Oncogene. 26:4124-4134
Reovirus shows considerable potential as an oncolytic agent for Ras-activated tumors and is currently in clinical trials. Here we ask whether such tumor cell lines can acquire resistance to reoviral oncolysis. We challenged human HT1080 fibrosarcoma
Autor:
Manbok Kim
Publikováno v:
Journal of microbiology (Seoul, Korea). 53(4)
Naturally occurring oncolytic viruses are live, replication-proficient viruses that specifically infect human cancer cells while sparing normal cell counterparts. Since the eradication of smallpox in the 1970s with the aid of vaccinia viruses, the va