Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Manav Gupta"'
Autor:
Haikuo Zhang, Christine Fillmore Brainson, Shohei Koyama, Amanda J. Redig, Ting Chen, Shuai Li, Manav Gupta, Carolina Garcia-de-Alba, Margherita Paschini, Grit S. Herter-Sprie, Gang Lu, Xin Zhang, Bryan P. Marsh, Stephanie J. Tuminello, Chunxiao Xu, Zhao Chen, Xiaoen Wang, Esra A. Akbay, Mei Zheng, Sangeetha Palakurthi, Lynette M. Sholl, Anil K. Rustgi, David J. Kwiatkowski, J Alan Diehl, Adam J. Bass, Norman E. Sharpless, Glenn Dranoff, Peter S. Hammerman, Hongbin Ji, Nabeel Bardeesy, Dieter Saur, Hideo Watanabe, Carla F. Kim, Kwok-Kin Wong
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
The mechanisms that govern the transdifferentiation of lung adenocarcinomas (ADC) to squamous cell carcinoma (SCC) are not fully understood. Here, the authors show that EZH2 loss exacerbates the transdifferentiation of ADCs to SCCs as a result of chr
Externí odkaz:
https://doaj.org/article/0ce62822a53e4bae828250fb78660d57
Autor:
Haikuo Zhang, Christine Fillmore Brainson, Shohei Koyama, Amanda J. Redig, Ting Chen, Shuai Li, Manav Gupta, Carolina Garcia-de-Alba, Margherita Paschini, Grit S. Herter-Sprie, Gang Lu, Xin Zhang, Bryan P Marsh, Stephanie J. Tuminello, Chunxiao Xu, Zhao Chen, Xiaoen Wang, Esra A. Akbay, Mei Zheng, Sangeetha Palakurthi, Lynette M. Sholl, Anil K. Rustgi, David J. Kwiatkowski, J. Alan Diehl, Adam J. Bass, Norman E. Sharpless, Glenn Dranoff, Peter S. Hammerman, Hongbin Ji, Nabeel Bardeesy, Dieter Saur, Hideo Watanabe, Carla F. Kim, Kwok-Kin Wong
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-1 (2017)
Nature Communications 8: Article number: 14922 (2017); Published 7 April 2017; Updated 9 June 2017 The affiliation details for Hideo Watanabe are incorrect in this Article. The correct affiliation details for this author are given below: Department o
Externí odkaz:
https://doaj.org/article/4e12b4b3cd7948f3862b7e4f3fea9569
Autor:
Tyler Jacks, Jason D. Buenrostro, Aviv Regev, Carla F. Kim, Charles M. Rudin, Natasha Rekhtman, Gregory J. Riely, Roderick T. Bronson, Manav Gupta, Kevin Meli, Francisco J. Sánchez-Rivera, Peter M.K. Westcott, Vinay K. Kartha, Manon Miller, Adam J. Schoenfeld, Isabella Del Priore, Jonathan Y. Kim, Lydia P. DeAngelo, Manyuan Liu, Arjun Bhutkar, Lindsay M. LaFave, Sai Ma, Carla P. Concepcion
Supplementary Figures related to Figures 1-6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fc3d2abf491d2aed509bace98e32b78
https://doi.org/10.1158/2159-8290.22541081.v1
https://doi.org/10.1158/2159-8290.22541081.v1
Autor:
Tyler Jacks, Jason D. Buenrostro, Aviv Regev, Carla F. Kim, Charles M. Rudin, Natasha Rekhtman, Gregory J. Riely, Roderick T. Bronson, Manav Gupta, Kevin Meli, Francisco J. Sánchez-Rivera, Peter M.K. Westcott, Vinay K. Kartha, Manon Miller, Adam J. Schoenfeld, Isabella Del Priore, Jonathan Y. Kim, Lydia P. DeAngelo, Manyuan Liu, Arjun Bhutkar, Lindsay M. LaFave, Sai Ma, Carla P. Concepcion
Processed data for bulk RNA-seq of primary tumors isolated from KP, KPS-HET and KPS animals
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b34017cdb6d509327a6779c56532668
https://doi.org/10.1158/2159-8290.22541084
https://doi.org/10.1158/2159-8290.22541084
Autor:
Tyler Jacks, Jason D. Buenrostro, Aviv Regev, Carla F. Kim, Charles M. Rudin, Natasha Rekhtman, Gregory J. Riely, Roderick T. Bronson, Manav Gupta, Kevin Meli, Francisco J. Sánchez-Rivera, Peter M.K. Westcott, Vinay K. Kartha, Manon Miller, Adam J. Schoenfeld, Isabella Del Priore, Jonathan Y. Kim, Lydia P. DeAngelo, Manyuan Liu, Arjun Bhutkar, Lindsay M. LaFave, Sai Ma, Carla P. Concepcion
Processed data for bulk ATAC-seq of isogenic SMARCA4-WT and -KO cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d74e81c89c1f111fdc821cff53ec855d
https://doi.org/10.1158/2159-8290.22541096.v1
https://doi.org/10.1158/2159-8290.22541096.v1
Autor:
Tyler Jacks, Jason D. Buenrostro, Aviv Regev, Carla F. Kim, Charles M. Rudin, Natasha Rekhtman, Gregory J. Riely, Roderick T. Bronson, Manav Gupta, Kevin Meli, Francisco J. Sánchez-Rivera, Peter M.K. Westcott, Vinay K. Kartha, Manon Miller, Adam J. Schoenfeld, Isabella Del Priore, Jonathan Y. Kim, Lydia P. DeAngelo, Manyuan Liu, Arjun Bhutkar, Lindsay M. LaFave, Sai Ma, Carla P. Concepcion
Mutations and copy number alterations in PDX models used in this study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2727f2c645d5056a98ef4b1e7ac249c5
https://doi.org/10.1158/2159-8290.22541078
https://doi.org/10.1158/2159-8290.22541078
Autor:
Tyler Jacks, Jason D. Buenrostro, Aviv Regev, Carla F. Kim, Charles M. Rudin, Natasha Rekhtman, Gregory J. Riely, Roderick T. Bronson, Manav Gupta, Kevin Meli, Francisco J. Sánchez-Rivera, Peter M.K. Westcott, Vinay K. Kartha, Manon Miller, Adam J. Schoenfeld, Isabella Del Priore, Jonathan Y. Kim, Lydia P. DeAngelo, Manyuan Liu, Arjun Bhutkar, Lindsay M. LaFave, Sai Ma, Carla P. Concepcion
Processed data for bulk RNA-seq of isogenic SMARCA4-WT and -KO cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d52d8ecb56becd9d8e98ad0a4ad8581b
https://doi.org/10.1158/2159-8290.22541090
https://doi.org/10.1158/2159-8290.22541090
Autor:
Tyler Jacks, Jason D. Buenrostro, Aviv Regev, Carla F. Kim, Charles M. Rudin, Natasha Rekhtman, Gregory J. Riely, Roderick T. Bronson, Manav Gupta, Kevin Meli, Francisco J. Sánchez-Rivera, Peter M.K. Westcott, Vinay K. Kartha, Manon Miller, Adam J. Schoenfeld, Isabella Del Priore, Jonathan Y. Kim, Lydia P. DeAngelo, Manyuan Liu, Arjun Bhutkar, Lindsay M. LaFave, Sai Ma, Carla P. Concepcion
SMARCA4/BRG1 encodes for one of two mutually exclusive ATPases present in mammalian SWI/SNF chromatin remodeling complexes and is frequently mutated in human lung adenocarcinoma. However, the functional consequences of SMARCA4 mutation on tumor initi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53c444972f838f79de09a6a762799058
https://doi.org/10.1158/2159-8290.c.6549551.v1
https://doi.org/10.1158/2159-8290.c.6549551.v1
Autor:
Tyler Jacks, Jason D. Buenrostro, Aviv Regev, Carla F. Kim, Charles M. Rudin, Natasha Rekhtman, Gregory J. Riely, Roderick T. Bronson, Manav Gupta, Kevin Meli, Francisco J. Sánchez-Rivera, Peter M.K. Westcott, Vinay K. Kartha, Manon Miller, Adam J. Schoenfeld, Isabella Del Priore, Jonathan Y. Kim, Lydia P. DeAngelo, Manyuan Liu, Arjun Bhutkar, Lindsay M. LaFave, Sai Ma, Carla P. Concepcion
Processed data for CUT&RUN of isogenic SMARCA4-WT and -KO cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dbf27db74b4779f83dc7c5a53d81c15
https://doi.org/10.1158/2159-8290.22541093.v1
https://doi.org/10.1158/2159-8290.22541093.v1
Autor:
Carla F. Kim, Tyler Jacks, Steven A. Carr, Lee Zou, Kwok-Kin Wong, Aaron N. Hata, Alice T. Shaw, Roderick T. Bronson, Angeliki Karatza, Hai Hu, Fei Li, Audris Oh, Chendi Li, D.R. Mani, Monica Schenone, Caroline R. Stanclift, Mary C. Beytagh, Margherita Paschini, Antoine Simoneau, Jonathan Y. Kim, Patrizia Pessina, Francisco J. Sanchez-Rivera, Christine F. Brainson, Arjun Bhutkar, Hasmik Keshishian, Caroline G. Fahey, Carla P. Concepcion, Manav Gupta
Figure S1 shows detailed RNA-sequencing analysis of patient samples as well as murine isogenic cell lines. Also presented here is further characterization of human isogenic models of BRG1 loss.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba123dd21772c1f92dce43113c871efc
https://doi.org/10.1158/0008-5472.22425849
https://doi.org/10.1158/0008-5472.22425849