Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Manat, Kaur"'
Autor:
Brian C. Sanders, Suman Pokhrel, Audrey D. Labbe, Irimpan I. Mathews, Connor J. Cooper, Russell B. Davidson, Gwyndalyn Phillips, Kevin L. Weiss, Qiu Zhang, Hugh O’Neill, Manat Kaur, Jurgen G. Schmidt, Walter Reichard, Surekha Surendranathan, Jyothi Parvathareddy, Lexi Phillips, Christopher Rainville, David E. Sterner, Desigan Kumaran, Babak Andi, Gyorgy Babnigg, Nigel W. Moriarty, Paul D. Adams, Andrzej Joachimiak, Brett L. Hurst, Suresh Kumar, Tauseef R. Butt, Colleen B. Jonsson, Lori Ferrins, Soichi Wakatsuki, Stephanie Galanie, Martha S. Head, Jerry M. Parks
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
The development of direct-acting antivirals to combat COVID-19 remains an important goal. Here the authors design covalent inhibitors that target the papain-like protease from SARS-CoV-2. The most promising inhibitor blocks viral replication in mamma
Externí odkaz:
https://doaj.org/article/fd261a622e08487782f550c5d0f5bc31
Autor:
Hasan, DeMirci, Yashas, Rao, Gabriele M, Stoffel, Bastian, Vögeli, Kristina, Schell, Aharon, Gomez, Alexander, Batyuk, Cornelius, Gati, Raymond G, Sierra, Mark S, Hunter, E Han, Dao, Halil I, Ciftci, Brandon, Hayes, Fredric, Poitevin, Po-Nan, Li, Manat, Kaur, Kensuke, Tono, David Adrian, Saez, Samuel, Deutsch, Yasuo, Yoshikuni, Helmut, Grubmüller, Tobias J, Erb, Esteban, Vöhringer-Martinez, Soichi, Wakatsuki
Publikováno v:
ACS central science. 8(8)
Enoyl-CoA carboxylases/reductases (ECRs) are some of the most efficient CO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c5915fda2947c222ad37cac1b99567c0
https://pubmed.ncbi.nlm.nih.gov/36032767
https://pubmed.ncbi.nlm.nih.gov/36032767
Autor:
Hasan DeMirci, Yashas Rao, Gabriele M. Stoffel, Bastian Vögeli, Kristina Schell, Aharon Gomez, Alexander Batyuk, Cornelius Gati, Raymond G. Sierra, Mark S. Hunter, E. Han Dao, Halil I. Ciftci, Brandon Hayes, Fredric Poitevin, Po-Nan Li, Manat Kaur, Kensuke Tono, David Adrian Saez, Samuel Deutsch, Yasuo Yoshikuni, Helmut Grubmüller, Tobias J. Erb, Esteban Vöhringer-Martinez, Soichi Wakatsuki
Publikováno v:
ACS central science, vol 8, iss 8
ACS Central Science
ACS Central Science
Enoyl-CoA carboxylases/reductases (ECRs) are some of the most efficient CO2-fixing enzymes described to date. However, the molecular mechanisms underlying the extraordinary catalytic activity of ECRs on the level of the protein assembly remain elusiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05fa966255720bcfdf2395cc9e451cb7
https://escholarship.org/uc/item/9064b000
https://escholarship.org/uc/item/9064b000
Autor:
Brian C. Sanders, Suman Pokhrel, Audrey D. Labbe, Irimpan I. Mathews, Connor J. Cooper, Russell B. Davidson, Gwyndalyn Phillips, Kevin L. Weiss, Qiu Zhang, Hugh O’Neill, Manat Kaur, Jurgen G. Schmidt, Walter Reichard, Surekha Surendranathan, Jyothi Parvathareddy, Lexi Phillips, Christopher Rainville, David E. Sterner, Desigan Kumaran, Babak Andi, Gyorgy Babnigg, Nigel W. Moriarty, Paul D. Adams, Andrzej Joachimiak, Brett L. Hurst, Suresh Kumar, Tauseef R. Butt, Colleen B. Jonsson, Lori Ferrins, Soichi Wakatsuki, Stephanie Galanie, Martha S. Head, Jerry M. Parks
Publikováno v:
Nature communications, vol 14, iss 1
Direct-acting antivirals are needed to combat coronavirus disease 2019 (COVID-19), which is caused by severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2). The papain-like protease (PLpro) domain of Nsp3 from SARS-CoV-2 is essential for viral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24bd8877103d685e79e5f39fdc0339f5
https://doi.org/10.21203/rs.3.rs-1840200/v1
https://doi.org/10.21203/rs.3.rs-1840200/v1
Autor:
Irimpan I. Mathews, Jerry M. Parks, Walter Reichard, Surekha Surendranathan, Gyorgy Babnigg, Desigan Kumaran, Lori Ferrins, Hugh O'Neill, Stephanie Galanie, Russell B. Davidson, Paul D. Adams, Suman Pohkrel, Soichi Wakatsuki, Nigel W. Moriarty, Kevin L. Weiss, Brian C. Sanders, Gwyndalyn Phillips, Audrey Labbe, Jurgen G. Schmidt, Babak Andi, Martha S Head, Andrzej Joachimiak, Qiu Zhang, Manat Kaur, Connor J. Cooper, Colleen B. Jonsson
Publikováno v:
Research Square
article-version (status) pre
article-version (number) 1
article-version (status) pre
article-version (number) 1
Direct-acting antivirals for the treatment of COVID-19, which is caused by severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), are needed to complement vaccination efforts. The papain-like protease (PLpro) of SARS-CoV-2 is essential for vir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b46ce2d1ff6c7c2f5efbd2aa21d4637e
http://europepmc.org/articles/PMC8509099
http://europepmc.org/articles/PMC8509099
Autor:
Adriana Ann Garcia, Irimpan I. Mathews, Naoki Horikoshi, Tsutomu Matsui, Manat Kaur, Soichi Wakatsuki, Daria Mochly-Rosen
Publikováno v:
Journal of Biological Chemistry. 298:101610
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is a genetic trait that can cause hemolytic anemia. To date, over 150 nonsynonymous mutations have been identified in G6PD, with pathogenic mutations clustering near the dimer and/or tetramer interf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cd63a66b9f4d4f052d470b44d03beb1
https://doi.org/10.1016/j.jbc.2022.101610
https://doi.org/10.1016/j.jbc.2022.101610
Autor:
Hasan DeMirci, Yash Rao, Gabriele M. Stoffel, Bastian Vögeli, Kristina Schell, Aharon Gomez, Alexander Batyuk, Cornelius Gati, Raymond G. Sierra, Mark S. Hunter, E. Han Dao, Halil I. Ciftci, Brandon Hayes, Fredric Poitevin, Po-Nan Li, Manat Kaur, Kensuke Tono, David Adrian Saez, Samuel Deutsch, Yasuo Yoshikuni, Helmut Grubmüller, Tobias J. Erb, Esteban Vöhringer-Martinez, Soichi Wakatsuki
Enoyl-CoA carboxylases/reductases (ECRs) belong to the most efficient CO2-fixing enzymes described to date. However, the molecular mechanisms underlying ECR’s extraordinary catalytic activity on the level of the protein assembly remain elusive. Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7072a23d24ee89cfb0655c9465f54bd
https://doi.org/10.1101/607101
https://doi.org/10.1101/607101