Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Manasi Barath"'
Autor:
Richard Austin, Thomas Evans, Jack Lin, Sony Rocha, Kathryn Kwant, Maria Dayao, Tessie Ng, Wade Aaron, Evan Callihan, Maria Gamez-Guerrero, Golzar Hemmati, Kevin Wright, Manasi Barath, Yinghua Xiao, Master Degree, Timothy Yu, Patrick Chew, Jessica O’Rear, Scott Gatto, Michael Cremin, Stephen Yu, Purbasa Patnaik, Avneel Hundal, Bryan Lemon, Holger Wesche
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/2a870365be484e02a43711d26308d88c
Autor:
Axel H. Schönthal, Florence M. Hofman, Natasha Sharma, Manasi Barath, Weijun Wang, Hee-Yeon Cho, Thomas C. Chen
PDF file - 320K, Supplementary Table S1: Drug sensitivities of cells transfected with MGMT cDNA; Supplementary Figure S1: Chemical structure of T-P; Supplementary Figure S2: Colony formation after drug treatment; Supplementary Figure S3: Histopatholo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d9108afe4f624a7b85443df9bd43533
https://doi.org/10.1158/1535-7163.22500258
https://doi.org/10.1158/1535-7163.22500258
Autor:
Axel H. Schönthal, Florence M. Hofman, Natasha Sharma, Manasi Barath, Weijun Wang, Hee-Yeon Cho, Thomas C. Chen
There is no effective therapy for breast cancer that has spread to the brain. A major roadblock is the blood–brain barrier (BBB), which prevents the usual breast cancer drugs from effectively reaching intracranial metastases. The alkylating agent t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::443a52fe127857ec63c791230ae12168
https://doi.org/10.1158/1535-7163.c.6536412.v1
https://doi.org/10.1158/1535-7163.c.6536412.v1
Autor:
Regina J. Lin, Sony S. Rocha, Maria R. Dayao, Subramanian Thothathri, Raphaela Rose Banzon, Kevin J. Wright, Wade Aaron, Yinghua Xiao, Nick Bergo, Linh To, Mabel Bush, Manasi Barath, Yi Yang, Timothy Yu, Willis Kwong, Hubert Situ, Eric Bragg, Jessica O'Rear, Kevin Carlin, Stephen Yu, Maritza Solorio, Bryan Lemon, Richard Austin, Holger Wesche, S. Jack Lin
Publikováno v:
Cancer Research. 83:2927-2927
Integrin-β6 (ITGB6) is a transmembrane protein that partners exclusively with the integrin-αV subunit to form the integrin-αVβ6 heterodimer. Due to its roles in tissue remodeling and cancer pathogenesis, therapeutic targeting of integrin-αVβ6 h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a9d00c7377764d7ed0f8c808962355c
https://doi.org/10.1158/1538-7445.am2023-2927
https://doi.org/10.1158/1538-7445.am2023-2927
Autor:
Sony S. Rocha, Regina Lin, Maria R. Dayao, Raphaela Rose Banzon, Subramanian Thothathri, Kevin J. Wright, Wade Aaron, Yinghua Xiao, Nick Bergo, Linh To, Mabel Bush, Manasi Barath, Timothy Yu, Willis Kwong, Hubert Situ, Eric Bragg, Jessica O'Rear, Kevin Carlin, Stephen Yu, Maritza Solorio, Bryan Lemon, Richard Austin, Holger Wesche, S. Jack Lin
Publikováno v:
Cancer Research. 83:2928-2928
Tumor-associated calcium signal transducer 2 (Trop2) is a cell surface glycoprotein that promotes cell renewal, proliferation and tumorigenesis. Trop2 is homogenously overexpressed in numerous solid tumor types, including breast, head and neck, prost
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a627f4564e09b6e1e4c7b31e14f37db1
https://doi.org/10.1158/1538-7445.am2023-2928
https://doi.org/10.1158/1538-7445.am2023-2928
Autor:
Lemon Bryan D, Manasi Barath, Che-Leung Law, Robert B. Dubridge, Kenneth Sexton, Richard J. Austin, Stephen Yu, Timothy Yu, Purbasa Patnaik, Patrick A. Baeuerle, A. Jones, Anand Panchal, Luke Evnin, Russell Wall, Patricia Culp, Kathryn L. Strobel, Pui Seto, Vanitha Ramakrishnan, Holger Wesche, Wade Aaron, Sony Rocha
Publikováno v:
Molecular Cancer Therapeutics. 20:109-120
T cells have a unique capability to eliminate cancer cells and fight malignancies. Cancer cells have adopted multiple immune evasion mechanisms aimed at inhibiting T cells. Dramatically improved patient outcomes have been achieved with therapies gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7405941cbbfa5d733a65e82cb28cafa8
https://doi.org/10.1158/1535-7163.mct-20-0061
https://doi.org/10.1158/1535-7163.mct-20-0061
Autor:
Kevin Wright, Jack Lin, Richard C. Austin, Maria Dayao, Lemon Bryan D, Master Degree, Michael Cremin, Stephen Yu, Purbasa Patnaik, Jessica O’Rear, Holger Wesche, Golzar Hemmati, Sony Rocha, Maria Gamez-Guerrero, Tessie M. Ng, Yinghua Xiao, Avneel Hundal, Scott Gatto, Kathryn Kwant, Tom Evans, Timothy Yu, Manasi Barath, Patrick Chew, Evan Callihan, Wade Aaron
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background Epithelial cell adhesion molecule (EpCAM) is highly expressed in many solid tumors. However, therapeutics targeting EpCAM have had limited clinical utility or failed in clinical development likely due to the expression of EpCAM in normal t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11e0492817e767fbfa910f853a5faa9b
https://doi.org/10.1136/jitc-2020-sitc2020.0632
https://doi.org/10.1136/jitc-2020-sitc2020.0632
Autor:
Timothy Yu, Raphaela Rose Banzon, Sony Rocha, Holger Wesche, Stephen Yu, Subramanian Thothathri, Yinghua Xiao, Jessica O’Rear, Kathryn Kwant, Kevin Wright, Purbasa Patnaik, Manasi Barath, Richard J. Austin, Avneel Hundal, S. Jack Lin, Golzar Hemmati, Lemon Bryan D, Tessie M. Ng, Scott Gatto, Wade Aaron, Evan Callihan, Linh To, Maria Dayao, Eric Bragg
Publikováno v:
Cancer Research. 81:933-933
T cell engagers have compelling clinical activity, but their use is limited by the availability of tumor targets with minimal normal tissue expression. Conditionally active T cell engagers designed to be active only in the tumor and to spare normal t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c82d09e115f10025f86264aee89fc782
https://doi.org/10.1158/1538-7445.am2021-933
https://doi.org/10.1158/1538-7445.am2021-933
Autor:
Stephen Yu, Kevin M. Wright, Jessica O’Rear, Manasi Barath, Wade Aaron, Lemon Bryan D, Morgan Thompson, Scott Gatto, Evan Callihan, Timothy Yu, Purbasa Patnaik, Holger Wesche, Che-Leung Law, Richard J. Austin, Lihn To, Golzar Hemmati, Yinghua Xiao
Publikováno v:
Cancer Research. 81:913-913
FLT3 (fms related receptor tyrosine kinase 3) is a cell surface protein expressed in hematopoietic stem and progenitor cell populations1. FLT3 RNA is overexpressed in greater than 95% of acute myeloid leukemia (AML) samples2, and FLT3 mutations are f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89d12e21da0bce7ca52255eafb28b34c
https://doi.org/10.1158/1538-7445.am2021-913
https://doi.org/10.1158/1538-7445.am2021-913