Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Manash K Paul"'
Autor:
Damayanti Das Ghosh, Hannah McDonald, Rajeswari Dutta, Keerthana Krishnan, Jaya Thilakan, Manash K. Paul, Neha Arya, Mahadev Rao, Vivek M. Rangnekar
Publikováno v:
Cells, Vol 13, Iss 21, p 1785 (2024)
Non-small cell lung cancer (NSCLC) has established predictive biomarkers that enable decisions on treatment regimens for many patients. However, resistance to therapy is widespread. It is therefore essential to have a panel of molecular biomarkers th
Externí odkaz:
https://doaj.org/article/94bd03e134ca40ab8503cdd668fbc111
Autor:
Prabhat K. Purbey, Joowon Seo, Manash K. Paul, Keisuke S. Iwamoto, Allison E. Daly, An-Chieh Feng, Ameya S. Champhekar, Justin Langerman, Katie M. Campbell, Dörthe Schaue, William H. McBride, Steven M. Dubinett, Antoni Ribas, Stephen T. Smale, Philip O. Scumpia
Publikováno v:
Cell Reports, Vol 43, Iss 6, Pp 114289- (2024)
Summary: Type I interferon (IFN-I) and IFN-γ foster antitumor immunity by facilitating T cell responses. Paradoxically, IFNs may promote T cell exhaustion by activating immune checkpoints. The downstream regulators of these disparate responses are i
Externí odkaz:
https://doaj.org/article/1aacdb1bc8d04f2aac55bcac0e7d97b6
Autor:
Aritraa Lahiri, Avik Maji, Pravin D. Potdar, Navneet Singh, Purvish Parikh, Bharti Bisht, Anubhab Mukherjee, Manash K. Paul
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-37 (2023)
Abstract Lung cancer is the primary cause of mortality in the United States and around the globe. Therapeutic options for lung cancer treatment include surgery, radiation therapy, chemotherapy, and targeted drug therapy. Medical management is often a
Externí odkaz:
https://doaj.org/article/c436e1feacb34ca2a269478a80f12339
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
Externí odkaz:
https://doaj.org/article/d79d863bb963460ab7ea4c0aa13aa956
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Externí odkaz:
https://doaj.org/article/2c9731fec4ee48be9e8f8a3f894e7f63
Autor:
Arkaprabha Basu, Manash K. Paul, Mitchel Alioscha-Perez, Anna Grosberg, Hichem Sahli, Steven M. Dubinett, Shimon Weiss
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-11 (2022)
A computational method for automated quantification of actin stress fiber alignment in fluorescence images of cultured cells is presented, used to detect changes in stress fiber organization during EMT, with pathways regulating actin dynamics manipul
Externí odkaz:
https://doaj.org/article/7ca65a79d5344b26bb93b4164b09418c
Autor:
Cody J. Aros, Manash K. Paul, Carla J. Pantoja, Bharti Bisht, Luisa K. Meneses, Preethi Vijayaraj, Jenna M. Sandlin, Bryan France, Jonathan A. Tse, Michelle W. Chen, David W. Shia, Tammy M. Rickabaugh, Robert Damoiseaux, Brigitte N. Gomperts
Publikováno v:
Cell Reports, Vol 30, Iss 7, Pp 2055-2064.e5 (2020)
Summary: Mechanisms underpinning airway epithelial homeostatic maintenance and ways to prevent its dysregulation remain elusive. Herein, we identify that β-catenin phosphorylated at Y489 (p-β-cateninY489) emerges during human squamous lung cancer p
Externí odkaz:
https://doaj.org/article/a599394ed7284d46981ea5a3afde29bc
Autor:
Chrianjay Mukhopadhyay, Manash K. Paul
Publikováno v:
Archives of Toxicology. 97:1429-1431
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42504271f31b35eeb37bc3c2c450c80a
https://doi.org/10.1007/s00204-023-03466-8
https://doi.org/10.1007/s00204-023-03466-8
Emergence of Cardiac Glycosides as Potential Drugs: Current and Future Scope for Cancer Therapeutics
Autor:
Ranjith Kumavath, Sayan Paul, Honey Pavithran, Manash K. Paul, Preetam Ghosh, Debmalya Barh, Vasco Azevedo
Publikováno v:
Biomolecules, Vol 11, Iss 9, p 1275 (2021)
Cardiac glycosides are natural sterols and constitute a group of secondary metabolites isolated from plants and animals. These cardiotonic agents are well recognized and accepted in the treatment of various cardiac diseases as they can increase the r
Externí odkaz:
https://doaj.org/article/d42af39ca2a344cf8e1d5732493a9732
Modeling Progressive Fibrosis with Pluripotent Stem Cells Identifies an Anti-fibrotic Small Molecule
Autor:
Preethi Vijayaraj, Aspram Minasyan, Abdo Durra, Saravanan Karumbayaram, Mehrsa Mehrabi, Cody J. Aros, Sarah D. Ahadome, David W. Shia, Katherine Chung, Jenna M. Sandlin, Kelly F. Darmawan, Kush V. Bhatt, Chase C. Manze, Manash K. Paul, Dan C. Wilkinson, Weihong Yan, Amander T. Clark, Tammy M. Rickabaugh, W. Dean Wallace, Thomas G. Graeber, Robert Damoiseaux, Brigitte N. Gomperts
Publikováno v:
Cell Reports, Vol 29, Iss 11, Pp 3488-3505.e9 (2019)
Summary: Progressive organ fibrosis accounts for one-third of all deaths worldwide, yet preclinical models that mimic the complex, progressive nature of the disease are lacking, and hence, there are no curative therapies. Progressive fibrosis across
Externí odkaz:
https://doaj.org/article/d90d9879ef6b4ac98aad3a2310cc1d88