Zobrazeno 1 - 10
of 1 067
pro vyhledávání: '"Manasanch A"'
The study of brain states, ranging from highly synchronous to asynchronous neuronal patterns like the sleep-wake cycle, is fundamental for assessing the brain's spatiotemporal dynamics and their close connection to behavior. However, the development
Externí odkaz:
http://arxiv.org/abs/2311.03421
Autor:
Alessandra Camassa, Melody Torao-Angosto, Arnau Manasanch, Morten L. Kringelbach, Gustavo Deco, Maria V. Sanchez-Vives
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract The brain is a complex non-equilibrium system capable of expressing many different dynamics as well as the transitions between them. We hypothesized that the level of non-equilibrium can serve as a signature of a given brain state, which was
Externí odkaz:
https://doaj.org/article/fa04176120584ac586a58b27ab8413e4
Autor:
Szymon J. Szymura, Lin Wang, Tiantian Zhang, Soung-chul Cha, Joo Song, Zhenyuan Dong, Aaron Anderson, Elizabeth Oh, Vincent Lee, Zhe Wang, Sapna Parshottam, Sheetal Rao, Jasper B. Olsem, Brandon N. Crumpton, Hans C. Lee, Elisabet E. Manasanch, Sattva Neelapu, Larry W. Kwak, Sheeba K. Thomas
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Lymphoplasmacytic lymphoma (LPL) is an incurable low-grade lymphoma with no standard therapy. Nine asymptomatic patients treated with a first-in-human, neoantigen DNA vaccine experienced no dose limiting toxicities (primary endpoint, NCT0120
Externí odkaz:
https://doaj.org/article/b4cc18ce434b4c7584d647c8e9b7b29b
Autor:
Gutzen, Robin, De Bonis, Giulia, De Luca, Chiara, Pastorelli, Elena, Capone, Cristiano, Mascaro, Anna Letizia Allegra, Resta, Francesco, Manasanch, Arnau, Pavone, Francesco Saverio, Sanchez-Vives, Maria V., Mattia, Maurizio, Grün, Sonja, Paolucci, Pier Stanislao, Denker, Michael
Neuroscience is moving towards a more integrative discipline, where understanding brain function requires consolidating the accumulated evidence seen across experiments, species, and measurement techniques. A remaining challenge on that path is integ
Externí odkaz:
http://arxiv.org/abs/2211.08527
Autor:
Natthakan Thongon, Feiyang Ma, Natalia Baran, Pamela Lockyer, Jintan Liu, Christopher Jackson, Ashley Rose, Ken Furudate, Bethany Wildeman, Matteo Marchesini, Valentina Marchica, Paola Storti, Giannalisa Todaro, Irene Ganan-Gomez, Vera Adema, Juan Jose Rodriguez-Sevilla, Yun Qing, Min Jin Ha, Rodrigo Fonseca, Caleb Stein, Caleb Class, Lin Tan, Sergio Attanasio, Guillermo Garcia-Manero, Nicola Giuliani, David Berrios Nolasco, Andrea Santoni, Claudio Cerchione, Carlos Bueso-Ramos, Marina Konopleva, Philip Lorenzi, Koichi Takahashi, Elisabet Manasanch, Gabriella Sammarelli, Rashmi Kanagal-Shamanna, Andrea Viale, Marta Chesi, Simona Colla
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract DNA damage resistance is a major barrier to effective DNA-damaging therapy in multiple myeloma (MM). To discover mechanisms through which MM cells overcome DNA damage, we investigate how MM cells become resistant to antisense oligonucleotide
Externí odkaz:
https://doaj.org/article/0ff32e3e332a47feb2ca0404a6595cec
Autor:
Sonia M. Setayesh, Libere J. Ndacayisaba, Kate E. Rappard, Valerie Hennes, Luz Yurany Moreno Rueda, Guilin Tang, Pei Lin, Robert Z. Orlowski, David E. Symer, Elisabet E. Manasanch, Stephanie N. Shishido, Peter Kuhn
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-10 (2023)
Abstract Multiple myeloma (MM) is accompanied by alterations to the normal plasma cell (PC) proteome, leading to changes to the tumor microenvironment and disease progression. There is a great need for understanding the consequences that lead to MM p
Externí odkaz:
https://doaj.org/article/a0b8d1a07e1b4a459e80c405e29213aa
Autor:
Mikkilineni, Lekha, Natrakul, Danielle A., Lam, Norris, Manasanch, Elisabet E., Mann, Jennifer, Weissler, Katherine A., Wong, Nathan, Brudno, Jennifer N., Goff, Stephanie L., Yang, James C., Ganaden, Micaela, Patel, Rashmika, Zheng, Zhili, Gartner, Jared J., Martin, Kathryn R., Wang, Hao-Wei, Yuan, Constance M., Lowe, Tyler, Maric, Irina, Shao, Lipei, Jin, Ping, Stroncek, David F., Highfill, Steven L., Rosenberg, Steven A., Kochenderfer, James N.
Publikováno v:
In Molecular Therapy 7 February 2024 32(2):503-526
Autor:
Gutzen, Robin, De Bonis, Giulia, De Luca, Chiara, Pastorelli, Elena, Capone, Cristiano, Allegra Mascaro, Anna Letizia, Resta, Francesco, Manasanch, Arnau, Pavone, Francesco Saverio, Sanchez-Vives, Maria V., Mattia, Maurizio, Grün, Sonja, Paolucci, Pier Stanislao, Denker, Michael
Publikováno v:
In Cell Reports Methods 22 January 2024 4(1)
Autor:
Nianyi Li, Pei Lin, Zhuang Zuo, M. James You, Wen Shuai, Robert Orlowski, Elisabet E. Manasanch, Shaoying Li, Jie Xu, Sofia Garces, Fatima Zahra Jelloul, Zhenya Tang, Wei Wang, L. Jeffrey Medeiros, C. Cameron Yin
Publikováno v:
Cancer Medicine, Vol 12, Iss 13, Pp 14293-14304 (2023)
Abstract BACKGROUND Mutations in the RAS‐MAPK pathway, such as KRAS, NRAS, and BRAF, are known as high‐risk factors associated with poor prognosis in patients with various cancers, but studies in myeloma have yielded mixed results. METHODS We des
Externí odkaz:
https://doaj.org/article/b57465017f294358af62a22940905108
Autor:
Elisabet Manasanch, Hannah Taylor, Gabrielle M Hernandez, Eva K Verzani, Claudia Ctortecka, David A Berrios Nolasco, Karl R Clauser, Namrata D Udeshi, Jennifer G Abelin, Steven A Carr
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 2 (2023)
Externí odkaz:
https://doaj.org/article/e7b07ad65578471a985b7cbe13da9d64