Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Manas K. Haldar"'
Autor:
Fataneh Karandish, Manas K. Haldar, Seungyong You, Amanda E. Brooks, Benjamin D. Brooks, Bin Guo, Yongki Choi, Sanku Mallik
Publikováno v:
ACS Omega, Vol 1, Iss 5, Pp 952-962 (2016)
Externí odkaz:
https://doaj.org/article/c0d3b30c47554a24b836493504cdfe73
Autor:
Manas K. Haldar, D. K. Srivastava, Sanku Mallik, Junru Yu, Abbas Sedigh, Yongki Choi, Seungyong You, James Froberg
Publikováno v:
Chemical Communications. 53:3307-3310
Using single-molecule approaches, we directly observed the dynamic interaction between HDAC8 and various ligands as well as conformational interconversions during the catalytic reaction. Statistical analysis identified key kinetic parameters, demonst
Autor:
Manas K. Haldar, Amanda E. Brooks, Fataneh Karandish, Yongki Choi, Benjamin D. Brooks, Seungyong You, Bin Guo, Sanku Mallik
Publikováno v:
ACS Omega, Vol 1, Iss 5, Pp 952-962 (2016)
ACS Omega
ACS Omega
Prostate cancer cells overexpress the prostate-specific membrane antigen (PSMA) receptors on the surface. Targeting the PSMA receptor creates a unique opportunity for drug delivery. Docetaxel is a Food and Drug Administration-approved drug for treati
Autor:
Fataneh Karandish, Manas K. Haldar, Li Feng, Babak Mamnoon, Lang Xia, Seungyong You, Kara N. Gange, Yongki Choi, Kausik Sarkar, Sanku Mallik
Publikováno v:
Biomacromolecules. 19(10)
Chemotherapeutic agents for treating cancers show considerable side effects, toxicity, and drug resistance. To mitigate the problems, we designed nucleus-targeted, echogenic, stimuli-responsive polymeric vesicles (polymersomes) to transport and subse
Autor:
Sanku Mallik, Fataneh Karandish, Kara N. Gange, Lang Xia, Matthew Confeld, Prajakta Kulkarni, Rayat Hossain, Manas K. Haldar, Kausik Sarkar, Pawel P. Borowicz
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 24(48)
Hypoxia in solid tumors facilitates the progression of the disease, develops resistance to chemo and radiotherapy, and contributes to relapse. Due to the lack of tumor penetration, most of the reported drug carriers are unable to reach the hypoxic ni
Autor:
Manas K. Haldar, Yongki Choi, John B. Shabb, D. K. Srivastava, Wallace W. Muhonen, Heather Wasness, Abbas Sedigh, Seth Oberlander, Shahjahan Molla, Tayebeh Anajafi, Jamie Froberg, Junru Yu, Kalpana S. Katti, Sanku Mallik
Publikováno v:
Molecular pharmaceutics. 14(6)
Improving the therapeutic index of anticancer agents is an enormous challenge. Targeting decreases the side effects of the therapeutic agents by delivering the drugs to the intended destination. Nanocarriers containing the nuclear localizing peptide
Publikováno v:
International Journal of Environmental Science and Development, Vol 4, Iss 6, Pp 681-687 (2013)
This paper examines the possible incorporation of solar and wind power in the East Malaysia power grid. Possible sites for solar and wind power generations are considered. Results from the simulation of the renewables integrated with the existing pow
Autor:
Sanku Mallik, Travis Leedahl, Raushan K. Singh, Abigail McGillivray, Naveena Lall, Manas K. Haldar, D. K. Srivastava, Tanmay Mandal, Gregory R. Cook
Publikováno v:
Biochemistry. 52:8139-8149
Of the different hydroxamate-based histone deacetylase (HDAC) inhibitors, suberoylanilide hydroxamic acid (SAHA) has been approved by the Food and Drug Administration for the treatment of T-cell ly...
Autor:
Prajakta Kulkarni, Preeya Katti, Yongki Choi, Courtney Dawes, Sanku Mallik, Manas K. Haldar, Seungyong You
Solid tumors are often poorly irrigated due to structurally compromised microcirculation. Uncontrolled multiplication of cancer cells, insufficient blood flow, and the lack of enough oxygen and nutrients lead to the development of hypoxic regions in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e0cacff8bddf66ab215e4e25accee93
https://europepmc.org/articles/PMC5502747/
https://europepmc.org/articles/PMC5502747/
Publikováno v:
Biomacromolecules. 17(8)
Hypoxia in tumors contributes to overall tumor progression by assisting in epithelial-to-mesenchymal transition, angiogenesis, and metastasis of cancer. In this study, we have synthesized a hypoxia-responsive, diblock copolymer poly(lactic acid)–az