Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Manami Maeda"'
Autor:
Yumi Takiyama, Toshihiro Sera, Masanori Nakamura, Kanaki Ishizeki, Yasuaki Saijo, Tsuyoshi Yanagimachi, Manami Maeda, Ryoichi Bessho, Takao Takiyama, Hiroya Kitsunai, Hidemitsu Sakagami, Daisuke Fujishiro, Yukihiro Fujita, Yuichi Makino, Atsuko Abiko, Masato Hoshino, Kentaro Uesugi, Naoto Yagi, Tsuguhito Ota, Masakazu Haneda
Publikováno v:
EBioMedicine, Vol 36, Iss , Pp 329-346 (2018)
Background: Recent large-scale clinical studies demonstrate that sodium-glucose cotransporter 2 (SGLT2) inhibitors protect the diabetic kidney. However, clinical and animal studies have not shown the changes of the total glomeruli in the whole kidney
Externí odkaz:
https://doaj.org/article/e0c854294846408e9992931b31f45d40
Autor:
Yukio Suga, Nana Ikeda, Manami Maeda, Angelina Yukiko Staub, Tsutomu Shimada, Miwa Yonezawa, Hironori Kitade, Hideyuki Katsura, Morihiro Okada, Junko Ishizaki, Yoshimichi Sai, Ryo Matsushita
Publikováno v:
Journal of Pharmaceutical Health Care and Sciences, Vol 4, Iss 1, Pp 1-7 (2018)
Abstract Background Vascular pain is a common adverse drug reaction in colorectal cancer patients receiving peripheral venous administration of oxaliplatin. The aim of this work was to identify risk factors for vascular pain, and to examine whether c
Externí odkaz:
https://doaj.org/article/f015447563464ab68b97298c3638b85e
Autor:
Jacky Chung, Johannes G Wittig, Alireza Ghamari, Manami Maeda, Tamara A Dailey, Hector Bergonia, Martin D Kafina, Emma E Coughlin, Catherine E Minogue, Alexander S Hebert, Liangtao Li, Jerry Kaplan, Harvey F Lodish, Daniel E Bauer, Stuart H Orkin, Alan B Cantor, Takahiro Maeda, John D Phillips, Joshua J Coon, David J Pagliarini, Harry A Dailey, Barry H Paw
Publikováno v:
eLife, Vol 6 (2017)
Heme is required for survival of all cells, and in most eukaryotes, is produced through a series of eight enzymatic reactions. Although heme production is critical for many cellular processes, how it is coupled to cellular differentiation is unknown.
Externí odkaz:
https://doaj.org/article/9d6ba52c921f43949ad7e7fd57b84d00
Autor:
Yuichi Ishikawa, Manami Maeda, Mithun Pasham, Francois Aguet, Silvia K. Tacheva-Grigorova, Takeshi Masuda, Hai Yi, Sung-Uk Lee, Jian Xu, Julie Teruya-Feldstein, Maria Ericsson, Ann Mullally, John Heuser, Tom Kirchhausen, Takahiro Maeda
Publikováno v:
Haematologica, Vol 100, Iss 4 (2015)
Clathrin-dependent endocytosis is an essential cellular process shared by all cell types. Despite this, precisely how endocytosis is regulated in a cell-type-specific manner and how this key pathway functions physiologically or pathophysiologically r
Externí odkaz:
https://doaj.org/article/55fb15d1f76e46a9a89852204ed5decb
Publikováno v:
Biological and Pharmaceutical Bulletin. 46:693-699
Autor:
Masakazu Haneda, Masanori Nakamura, Masato Hoshino, Naoto Yagi, Takao Takiyama, Yuichi Makino, Yasuaki Saijo, Kanaki Ishizeki, Tsuyoshi Yanagimachi, Yukihiro Fujita, Manami Maeda, Atsuko Abiko, Kentaro Uesugi, Hiroya Kitsunai, Yumi Takiyama, Tsuguhito Ota, Daisuke Fujishiro, Ryoichi Bessho, Toshihiro Sera, Hidemitsu Sakagami
Publikováno v:
EBioMedicine
Background Recent large-scale clinical studies demonstrate that sodium-glucose cotransporter 2 (SGLT2) inhibitors protect the diabetic kidney. However, clinical and animal studies have not shown the changes of the total glomeruli in the whole kidney
Autor:
Luca Pinello, Bruno Reversade, Takahiro Maeda, Yuichiro Semba, Michitaka Nakano, Takeshi Masuda, Matthew C. Canver, Qiuming Yao, Mohammad Shboul, Stuart H. Orkin, Manami Maeda, Silvia Buonamici, Vivien A. C. Schoonenberg, Michael Seiler, Yuichi Ishikawa, Mitchel A. Cole, Takuji Yamauchi, Daniel E. Bauer, Claudio Macias-Trevino, Fumio Arai, Mohammed Al-Raqad, Koichi Akashi
Publikováno v:
Cancer cell, 33(3), 386-400.e5. Cell Press
To identify novel targets for acute myeloid leukemia (AML) therapy, we performed genome-wide CRISPR-Cas9 screening using AML cell lines, followed by a second screen in vivo. Here, we show that the mRNA decapping enzyme scavenger (DCPS) gene is essent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78b707fc5be679825762265701ffb9f0
https://pure.amc.nl/en/publications/genomewide-crisprcas9-screen-identifies-leukemiaspecific-dependence-on-a-premrna-metabolic-pathway-regulated-by-dcps(633460b1-83da-4b6e-8588-1fb565c1e3c3).html
https://pure.amc.nl/en/publications/genomewide-crisprcas9-screen-identifies-leukemiaspecific-dependence-on-a-premrna-metabolic-pathway-regulated-by-dcps(633460b1-83da-4b6e-8588-1fb565c1e3c3).html
Autor:
Kanaki Ishizeki, Yuichi Makino, Daisuke Fujishiro, Hiroya Kitsunai, Toshihiro Sera, Yukihiro Fujita, Yasuaki Saijo, Tsuyoshi Yanagimachi, Masanori Nakamaura, Takao Takiyama, Masakazu Haneda, Naoto Yagi, Atsuko Abiko, Masato Hoshino, Ryoichi Bessho, Tsuguhito Ota, Yumi Takiyama, Hidemitsu Sakagami, Kentaro Uesugi, Manami Maeda
Publikováno v:
SSRN Electronic Journal.
To investigate the impact of diabetes and luseogliflozin, a sodium-glucose cotransporter 2 (SGLT2) inhibitor on the numbers and volumes of glomeruli in the whole kidneys, we performed CT imaging of diabetic db/db mice using synchrotron radiation at S
Autor:
Julie A. Schneider, Zhen Zhao, Qingyi Ma, Ethan A. Winkler, Anita Ramanathan, Takahiro Maeda, Ashim Ahuja, Justin K. Ichida, Carol A. Miller, Pan Kong, Matthew R. Halliday, Guojun Bu, Takahisa Kanekiyo, Sanket V Rege, Manami Maeda, Tohru Sugawara, Berislav V. Zlokovic, Donghui Zhu, Kassandra Kisler, Abhay P. Sagare, Nelly Chuqui Owens, Gabriel Si
Publikováno v:
Nature neuroscience
PICALM is a highly validated genetic risk factor for Alzheimer's disease (AD). We found that reduced expression of PICALM in AD and murine brain endothelium correlated with amyloid-β (Aβ) pathology and cognitive impairment. Moreover, Picalm deficie
Autor:
Alexander S. Hebert, Catherine E. Minogue, Daniel E. Bauer, John D. Phillips, Tamara A. Dailey, Liangtao Li, Emma E. Coughlin, Jacky Chung, Hector A. Bergonia, Alan B. Cantor, Takahiro Maeda, Joshua J. Coon, Harry A. Dailey, Martin D. Kafina, Harvey F. Lodish, Barry H. Paw, Manami Maeda, Stuart H. Orkin, Alireza Ghamari, Jerry Kaplan, David J. Pagliarini, Johannes G. Wittig
Publikováno v:
eLife, Vol 6 (2017)
eLife
eLife
Heme is required for survival of all cells, and in most eukaryotes, is produced through a series of eight enzymatic reactions. Although heme production is critical for many cellular processes, how it is coupled to cellular differentiation is unknown.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64864df498d5f9e01442e403f098522e
https://ueaeprints.uea.ac.uk/id/eprint/63655/
https://ueaeprints.uea.ac.uk/id/eprint/63655/