Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Manali Dimri"'
Autor:
Kevin Tae, Manali Dimri, Livesay J, Muslim Ma, Lain X. Pierce, Allyson McClendon, Tuscano Km, Gregory Naegele, Liu Jl, Isabel Gibson, Ortega Kl, Singh Dj, Lee W, Takuya F. Sakaguchi
Impaired formation of the biliary network can lead to congenital cholestatic liver diseases; however, the genes responsible for proper biliary system formation and maintenance have not been fully identified. Combining computational network structure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f58efdac0cf5b932582de14e766c431c
https://doi.org/10.1101/2021.06.22.449425
https://doi.org/10.1101/2021.06.22.449425
Autor:
Ande Satyanarayana, Manali Dimri
Publikováno v:
Cancers, Vol 12, Iss 2, p 491 (2020)
Cancers
Cancers
Hepatocellular carcinoma (HCC) is a complex biological process and is often diagnosed at advanced stages with no effective treatment options. With advances in tumor biology and molecular genetic profiling, several different signaling pathways and mol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::034a237e49c80373b7512b1499466e48
https://www.mdpi.com/2072-6694/12/2/491
https://www.mdpi.com/2072-6694/12/2/491
Autor:
Isabel Gibson, Gregory Naegele, Amit Vasanji, Takuya F. Sakaguchi, Manali Dimri, Lain X. Pierce, Allyson McClendon, Kevin Tae, Cassandra Bilogan
Publikováno v:
Development. 144:2595-2605
The intrahepatic biliary network is a highly branched three-dimensional network lined by biliary epithelial cells, but how its branching patterns are precisely established is not clear. We designed a new computer-based algorithm that quantitatively c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a77a55e884e1c18af396fb8151f3a7b1
https://doi.org/10.1242/dev.147397
https://doi.org/10.1242/dev.147397
Autor:
Manali Dimri, Ashley Humphries, Archana Laknaur, Sawsan Elattar, Ashok Sharma, Ravindra Kolhe, Ande Satyanarayana
Publikováno v:
Cancer Research. 79:1835-1835
According to the World Health Organization, hepatocellular carcinoma (HCC) is the 2nd leading cause of cancer related deaths worldwide. HCC is highly resistant to conventional chemotherapies; therefore, identification of specific molecular targets fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a52cb895ededaf1db601ba9facaa0291
https://doi.org/10.1158/1538-7445.am2019-1835
https://doi.org/10.1158/1538-7445.am2019-1835
Autor:
Ashley Humphries, Archana Laknaur, Ashok Sharma, Ravindra Kolhe, Manali Dimri, Ande Satyanarayana, Sawsan Elattar, Tae Jin Lee
Publikováno v:
Hepatology
Cancer cells undergo metabolic adaptation to sustain uncontrolled proliferation. Aerobic glycolysis and glutaminolysis are two of the most essential characteristics of cancer metabolic reprogramming. Hyperactivated phosphoinositide 3-kinase (PI3K)/Ak
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af3775f38e87951b3ff086551ae751df
https://pubmed.ncbi.nlm.nih.gov/31215069
https://pubmed.ncbi.nlm.nih.gov/31215069
Cachexia is a complex tissue-wasting syndrome characterized by inflammation, hypermetabolism, increased energy expenditure, and anorexia. Browning of white adipose tissue (WAT) is one of the significant factors that contribute to energy wasting in ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::919ea7c110aff373583432d529e3866e
https://europepmc.org/articles/PMC6266632/
https://europepmc.org/articles/PMC6266632/
Autor:
Rina Chakraborti, Neeta Sehgal, Jayadev Joshi, Subhajit Ghosh, Nitisha Shrivastava, Jharna Ray, Manali Dimri, Indracanti Prem Kumar
Publikováno v:
Current Computer Aided-Drug Design. 11:222-236
Ligand bound beta 2 adrenergic receptor (β2AR) crystal structures are in use for screening of compound libraries for identifying inducers and blockers. However, in case of G protein coupled receptors (GPCR), docking and binding energy (BE) calculati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fabcf40470089cf13c29ea2c857986b
https://doi.org/10.2174/1573409911666150812130420
https://doi.org/10.2174/1573409911666150812130420
Autor:
Indracanti Prem Kumar, Manali Dimri, Angara Sureshbabu, Rina Chakrabarti, Neeta Sehgal, Jayadev Joshi
Publikováno v:
Zebrafish. 12:33-47
The Johns Hopkins Clinical Compound Library (JHCCL), a collection of Food and Drug Administration (FDA)-approved small molecules (1400), was screened in silico for identification of novel β2AR blockers and tested for hematopoietic stem cell (HSC) ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa5af5c145e6f9bccbbe4f7b8f8e9476
https://doi.org/10.1089/zeb.2014.0992
https://doi.org/10.1089/zeb.2014.0992
Publikováno v:
Gastroenterology. 152:S1238
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c26aea391e026a4a669cc174fb2e6491
https://doi.org/10.1016/s0016-5085(17)34119-7
https://doi.org/10.1016/s0016-5085(17)34119-7
Autor:
Manali, Dimri, Jayadev, Joshi, Nitisha, Shrivastava, Subhajit, Ghosh, Rina, Chakraborti, Prem Kumar, Indracanti
Publikováno v:
The Tokai journal of experimental and clinical medicine. 40(1)
Drug repositioning is an approach of significant translatability, and the present study was undertaken to screen a collection of FDA approved small-molecule clinical compounds for identification of novel radioprotective agents. Screening of JHCCL (Jo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ee785a9b359a40d95a9b59c56576b77c
https://pubmed.ncbi.nlm.nih.gov/25843444
https://pubmed.ncbi.nlm.nih.gov/25843444