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pro vyhledávání: '"Manali Banerjee"'
Autor:
Manali Banerjee, Blair Brettmann
Publikováno v:
Pharmaceutics, Vol 13, Iss 4, p 441 (2021)
Indomethacin (IM) is a small molecule active pharmaceutical ingredient (API) that exhibits polymorphism with the γ-form being the most thermodynamically stable form of the drug. The α-form is metastable, but it exhibits higher solubility, making it
Externí odkaz:
https://doaj.org/article/76484fcbfc2e4bc7ab551ca3cc34e7f2
Autor:
Manali Banerjee, Blair Brettmann
Publikováno v:
Pharmaceutics, Vol 12, Iss 10, p 995 (2020)
Poor water solubility is one of the major challenges to the development of oral dosage forms containing active pharmaceutical ingredients (APIs). Polymorphism in APIs leads to crystals with different surface wettabilities and free energies, which can
Externí odkaz:
https://doaj.org/article/ea35e8c97749468db9ecdbf173aaaf6e
Publikováno v:
Physical chemistry chemical physics : PCCP. 24(43)
We present machine learning models trained on experimental data to predict room-temperature solubility for any polymer-solvent pair. The new models are a significant advancement over past data-driven work, in terms of protocol, validity, and versatil
Autor:
Manali Banerjee, Tomasz Kowalewski, Andria Fortney, Kevin J. T. Noonan, David Yaron, Chia-Hua Tsai
Publikováno v:
Macromolecules. 51:9494-9501
Controlling the sequence of repeat units in a synthetic polymer has been a long-standing topic of interest in chemistry. As methods to regulate sequence become more sophisticated, it is critical to consider how controlling the arrangement of repeat u
Publikováno v:
Polymer. 153:529-537
Electrospinning is a valuable production method for nanoscale polymeric fibers. A major limitation of the technology is the requirement for high molecular weight polymers as a major part of the matrix. Many applications would benefit from flexibility
Autor:
Manali Banerjee, Sisira Saraswatula, Laura Grace Willows, Blair K. Brettmann, Hannah K. Woods
Publikováno v:
Journal of Materials Chemistry B. 6:7317-7328
A significant research focus in the pharmaceutical industry is on methods to improve drug uptake into the body by increased dissolution of poorly water soluble active pharmaceutical ingredients (APIs) or sustained drug release behavior, which results
Autor:
Blair K. Brettmann, Manali Banerjee
Publikováno v:
Pharmaceutics, Vol 12, Iss 995, p 995 (2020)
Pharmaceutics
Pharmaceutics
Poor water solubility is one of the major challenges to the development of oral dosage forms containing active pharmaceutical ingredients (APIs). Polymorphism in APIs leads to crystals with different surface wettabilities and free energies, which can
Publikováno v:
Processes
Volume 8
Issue 6
Processes, Vol 8, Iss 698, p 698 (2020)
Volume 8
Issue 6
Processes, Vol 8, Iss 698, p 698 (2020)
Cellulose nanocrystals (CNCs) are attractive for use in polymer composites, biomedical applications, and barrier packaging. In all of these applications they are mixed with other components and compatibility is a major design consideration, as CNCs n