Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Manabu Taneike"'
Autor:
Tomokazu Murakawa, Jumpei Ito, Mara-Camelia Rusu, Manabu Taneike, Shigemiki Omiya, Javier Moncayo-Arlandi, Chiaki Nakanishi, Ryuta Sugihara, Hiroki Nishida, Kentaro Mine, Roland Fleck, Min Zhang, Kazuhiko Nishida, Ajay M. Shah, Osamu Yamaguchi, Yasushi Sakata, Kinya Otsu
Publikováno v:
Cell Reports, Vol 43, Iss 12, Pp 115001- (2024)
Summary: The accumulation of damaged mitochondria in the heart is associated with heart failure. Mitophagy is an autophagic degradation system that specifically targets damaged mitochondria. We have reported previously that Bcl2-like protein 13 (Bcl2
Externí odkaz:
https://doaj.org/article/c820a74c6b29403f9a0f39246e95d746
Autor:
Ryuta Sugihara, Manabu Taneike, Tomokazu Murakawa, Takahito Tamai, Hiromichi Ueda, Rika Kitazume-Taneike, Takafumi Oka, Yasuhiro Akazawa, Hiroki Nishida, Kentaro Mine, Ayana Hioki, Jumpei Omi, Shigemiki Omiya, Junken Aoki, Kazutaka Ikeda, Kazuhiko Nishida, Makoto Arita, Osamu Yamaguchi, Yasushi Sakata, Kinya Otsu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Heart failure is a leading cause of mortality in developed countries. Cell death is a key player in the development of heart failure. Calcium-independent phospholipase A2β (iPLA2β) produces lipid mediators by catalyzing lipids and induces
Externí odkaz:
https://doaj.org/article/03449b4053ed4690b7fd3c190b592a8e
Autor:
Yasuhiro Akazawa, Manabu Taneike, Hiromichi Ueda, Rika Kitazume-Taneike, Tomokazu Murakawa, Ryuta Sugihara, Hiroki Yorifuji, Hiroki Nishida, Kentaro Mine, Ayana Hioki, Shigemiki Omiya, Hiroyuki Nakayama, Osamu Yamaguchi, Tamotsu Yoshimori, Yasushi Sakata, Kinya Otsu
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Heart failure has high morbidity and mortality in the developed countries. Autophagy is important for the quality control of proteins and organelles in the heart. Rubicon (Run domain Beclin-1-interacting and cysteine-rich domain-containing p
Externí odkaz:
https://doaj.org/article/d95a4c18411e4cd2b66f11ef98bf7f2c
Autor:
Manabu Taneike, Makoto Nishida, Kaori Nakanishi, Fusako Sera, Hidetaka Kioka, Ryohei Yamamoto, Tomohito Ohtani, Shungo Hikoso, Toshiki Moriyama, Yasushi Sakata, Keiko Yamauchi-Takihara
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Heart failure is a major cause of death with an increasing population of elderly individuals. Several studies have demonstrated the involvement of soluble alpha-Klotho (sαKl) in various diseases. However, the correlation between sαKl and h
Externí odkaz:
https://doaj.org/article/e90d8e9e631c4da4814eea00182a7c4e
Autor:
Hiromichi Ueda, MD, Osamu Yamaguchi, MD, PhD, Manabu Taneike, MD, PhD, Yasuhiro Akazawa, MD, Haruko Wada-Kobayashi, MD, Ryuta Sugihara, MD, Hiroki Yorifuji, MD, Hiroyuki Nakayama, MD, PhD, Shigemiki Omiya, MD, PhD, Tomokazu Murakawa, MD, PhD, Yasushi Sakata, MD, PhD, Kinya Otsu, MD, PhD
Publikováno v:
JACC: Basic to Translational Science, Vol 4, Iss 3, Pp 348-363 (2019)
Summary: Mitochondrial deoxyribonucleic acid, containing the unmethylated cytidine-phosphate-guanosine motif, stimulates Toll-like receptor 9 to induce inflammation and heart failure. A small chemical, E6446 [(6-[3-(pyrrolidin-1-yl)propoxy)-2-(4-(3-(
Externí odkaz:
https://doaj.org/article/86de2b18a91f4c5cb7698ac03bf329b4
Autor:
Jumpei Ito, Shigemiki Omiya, Mara-Camelia Rusu, Hiromichi Ueda, Tomokazu Murakawa, Yohei Tanada, Hajime Abe, Kazuki Nakahara, Michio Asahi, Manabu Taneike, Kazuhiko Nishida, Ajay M Shah, Kinya Otsu
Publikováno v:
eLife, Vol 10 (2021)
Heart failure is a major public health problem, and abnormal iron metabolism is common in patients with heart failure. Although iron is necessary for metabolic homeostasis, it induces a programmed necrosis. Iron release from ferritin storage is throu
Externí odkaz:
https://doaj.org/article/d7ee8c4057a14ed1a17e5078bbd36987
Autor:
Tomokazu Murakawa, Koji Okamoto, Shigemiki Omiya, Manabu Taneike, Osamu Yamaguchi, Kinya Otsu
Publikováno v:
Cell Reports, Vol 26, Iss 2, Pp 338-345.e6 (2019)
Summary: Degradation of mitochondria by selective autophagy, termed mitophagy, contributes to the control of mitochondrial quality. Bcl2-L-13 is a mammalian homolog of Atg32, which is an essential mitophagy receptor in yeast. However, the molecular m
Externí odkaz:
https://doaj.org/article/a280779082c14d2c8b06788263d42ed6
Autor:
Manabu Taneike, Kazuhiko Nishida, Shigemiki Omiya, Elham Zarrinpashneh, Tomofumi Misaka, Rika Kitazume-Taneike, Ruth Austin, Minoru Takaoka, Osamu Yamaguchi, Michael J Gambello, Ajay M Shah, Kinya Otsu
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0152628 (2016)
Mammalian target of rapamycin complex 1 (mTORC1) is a key regulator of cell growth, proliferation and metabolism. mTORC1 regulates protein synthesis positively and autophagy negatively. Autophagy is a major system to manage bulk degradation and recyc
Externí odkaz:
https://doaj.org/article/a8d9d33d3798448694e97654cac47306
Publikováno v:
Journal of Molecular and Cellular Cardiology. 173:11-12
Autor:
Kaori Nakanishi, Makoto Nishida, Manabu Taneike, Keiko Yamauchi-Takihara, Toshiki Moriyama, Ryohei Yamamoto
Publikováno v:
International Journal of General Medicine
Kaori Nakanishi, Makoto Nishida, Manabu Taneike, Ryohei Yamamoto, Toshiki Moriyama, Keiko Yamauchi-Takihara Health Care Division, Health and Counseling Center, Osaka University, Osaka, JapanCorrespondence: Keiko Yamauchi-TakiharaHealth Care Division,