Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Manabu Sotomatsu"'
Autor:
Norio Shiba, Kenichi Yoshida, Yusuke Hara, Genki Yamato, Yuichi Shiraishi, Hidemasa Matsuo, Yusuke Okuno, Kenichi Chiba, Hiroko Tanaka, Taeko Kaburagi, Masanobu Takeuchi, Kentaro Ohki, Masashi Sanada, Jun Okubo, Daisuke Tomizawa, Tomohiko Taki, Akira Shimada, Manabu Sotomatsu, Keizo Horibe, Takashi Taga, Souichi Adachi, Akio Tawa, Satoru Miyano, Seishi Ogawa, Yasuhide Hayashi
Publikováno v:
Blood Advances, Vol 3, Iss 20, Pp 3157-3169 (2019)
Abstract: Recent advances in the genetic understanding of acute myeloid leukemia (AML) have improved clinical outcomes in pediatric patients. However, ∼40% of patients with pediatric AML relapse, resulting in a relatively low overall survival rate
Externí odkaz:
https://doaj.org/article/2ec3e3d04c7b43d39e264c81ce939535
Autor:
Taeko Kaburagi, Genki Yamato, Norio Shiba, Kenichi Yoshida, Yusuke Hara, Ken Tabuchi, Yuichi Shiraishi, Kentaro Ohki, Manabu Sotomatsu, Hirokazu Arakawa, Hidemasa Matsuo, Akira Shimada, Tomohiko Taki, Nobutaka Kiyokawa, Daisuke Tomizawa, Keizo Horibe, Satoru Miyano, Takashi Taga, Souichi Adachi, Seishi Ogawa, Yasuhide Hayashi
Publikováno v:
Haematologica, Vol 107, Iss 3 (2021)
RAS pathway alterations have been implicated in the pathogenesis of various hematological malignancies. However, their clinical relevance in pediatric acute myeloid leukemia (AML) is not well characterized. We analyzed the frequency, clinical signifi
Externí odkaz:
https://doaj.org/article/fdbcc55b426043c281c3397ca42dc1a5
Autor:
Yusuke Hara, Norio Shiba, Kenichi Yoshida, Genki Yamato, Taeko Kaburagi, Yuichi Shiraishi, Kentaro Ohki, Yusuke Shiozawa, Machiko Kawamura, Hirohide Kawasaki, Manabu Sotomatsu, Takumi Takizawa, Hidemasa Matsuo, Akira Shimada, Nobutaka Kiyokawa, Daisuke Tomizawa, Takashi Taga, Etsuro Ito, Keizo Horibe, Satoru Miyano, Souichi Adachi, Tomohiko Taki, Seishi Ogawa, Yasuhide Hayashi
Publikováno v:
Genes, Chromosomes and Cancer. 62:412-422
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6b2702e81d216c3c0345f42d741c555
https://doi.org/10.1002/gcc.23147
https://doi.org/10.1002/gcc.23147
Autor:
Genki Yamato, Tomoko Kawai, Norio Shiba, Junji Ikeda, Yusuke Hara, Kentaro Ohki, Shin-Ichi Tsujimoto, Taeko Kaburagi, Kenichi Yoshida, Yuichi Shiraishi, Satoru Miyano, Nobutaka Kiyokawa, Daisuke Tomizawa, Akira Shimada, Manabu Sotomatsu, Hirokazu Arakawa, Souichi Adachi, Takashi Taga, Keizo Horibe, Seishi Ogawa, Kenichiro Hata, Yasuhide Hayashi
Publikováno v:
Blood Advances. 6:3207-3219
We investigated genome-wide DNA methylation patterns in 64 pediatric patients with acute myeloid leukemia (AML). Based on unsupervised clustering with the 567 most variably methylated cytosine guanine dinucleotide (CpG) sites, patients were categoriz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7eb2be8cda868149fe6254a08c5508bc
https://doi.org/10.1182/bloodadvances.2021005381
https://doi.org/10.1182/bloodadvances.2021005381
Autor:
Taeko Kaburagi, Norio Shiba, Genki Yamato, Kenichi Yoshida, Ken Tabuchi, Kentaro Ohki, Etsuko Ishikita, Yusuke Hara, Yuichi Shiraishi, Hirohide Kawasaki, Manabu Sotomatsu, Takumi Takizawa, Tomohiko Taki, Nobutaka Kiyokawa, Daisuke Tomizawa, Keizo Horibe, Satoru Miyano, Takashi Taga, Souichi Adachi, Seishi Ogawa, Yasuhide Hayashi
Publikováno v:
Genes, chromosomescancerREFERENCES.
The prognosis of pediatric acute myeloid leukemia (AML) has improved via stratification therapy. However, relapse or death occurs in 30%-40% of cases. Novel genetic factors for pediatric AML need to be elucidated to improve prognosis. We detected rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d04ef0557f2ca5990deb73302f0b78cd
https://pubmed.ncbi.nlm.nih.gov/36448876
https://pubmed.ncbi.nlm.nih.gov/36448876
Autor:
Genki Yamato, Tomoko Kawai, Norio Shiba, Yusuke Hara, Kentaro Ohki, Taeko Kaburagi, Etsuko Ishikita, Hirohide Kawasaki, Kenichi Yoshida, Yuichi Shiraishi, Satoru Miyano, Nobutaka Kiyokawa, Daisuke Tomizawa, Akira Shimada, Manabu Sotomatsu, Takumi Takizawa, Souichi Adachi, Takashi Taga, Keizo Horibe, Seishi Ogawa, Kenichiro Hata, Yasuhide Hayashi
Publikováno v:
Blood. 140:9134-9135
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89c150cbd83d84736d8bf642cdefe7a0
https://doi.org/10.1182/blood-2022-163226
https://doi.org/10.1182/blood-2022-163226
Autor:
Akio Tawa, Akira Shimada, Kenichi Chiba, Yuichi Shiraishi, Masanobu Takeuchi, Souichi Adachi, Keizo Horibe, Daisuke Tomizawa, Yusuke Okuno, Taeko Kaburagi, Yasuhide Hayashi, Masashi Sanada, Takashi Taga, Norio Shiba, Yusuke Hara, Hiroko Tanaka, Satoru Miyano, Seishi Ogawa, Jun Okubo, Genki Yamato, Kentaro Ohki, Hidemasa Matsuo, Tomohiko Taki, Manabu Sotomatsu, Kenichi Yoshida
Publikováno v:
Blood Advances. 3:3157-3169
Recent advances in the genetic understanding of acute myeloid leukemia (AML) have improved clinical outcomes in pediatric patients. However, ∼40% of patients with pediatric AML relapse, resulting in a relatively low overall survival rate of ∼70%.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d705d739039e46b9b2ce134da871eac
https://doi.org/10.1182/bloodadvances.2019000404
https://doi.org/10.1182/bloodadvances.2019000404
Autor:
Akitoshi Kinoshita, Akio Tawa, Hirokazu Arakawa, Kentaro Ohki, Akiko Saito, Manabu Sotomatsu, Daisuke Tomizawa, Nobutaka Kiyokawa, Souichi Adachi, Tomohiko Taki, Keizo Horibe, Takashi Taga, Ken Tabuchi, Yasuhide Hayashi, Yusuke Hara, Genki Yamato, Norio Shiba
Publikováno v:
British Journal of Haematology. 188:528-539
Although infants (age
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef4ccca68aeea028c9e4d59a6434b893
https://doi.org/10.1111/bjh.16203
https://doi.org/10.1111/bjh.16203
Autor:
Akira Ohara, Shouichi Ohga, Akiko Saito, Keitaro Fukushima, Yasuhiro Okamoto, Keizo Horibe, Manabu Sotomatsu, Hirokazu Kanegane, Keiko Nomura, Yozo Nakazawa, Kazuyuki Matsuda, Eiichi Ishii, Akira Morimoto, Ryu Yanagaisawa
Publikováno v:
International Journal of Hematology. 109:612-617
Epstein-Barr virus (EBV)-associated hemophagocytic lymphohistiocytosis (HLH) is highly prevalent in Japan. To date, no standard treatment for EBV-HLH has been established owing to the diversity in treatment response and the difficulty in assessing pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::029a84236e8ee9ec1f798c9f5518f073
https://doi.org/10.1007/s12185-019-02612-2
https://doi.org/10.1007/s12185-019-02612-2
Autor:
Kentaro Ohki, Kenichi Maruyama, Myoung-ja Park, Kiyoko Sameshima, Manabu Sotomatsu, Akira Nishi, Yasuhide Hayashi, Genki Yamato, Takashi Kobayashi, Taeko Kaburagi
Publikováno v:
International journal of hematology. 113(5)
Transient abnormal myelopoiesis (TAM) is a unique clonal myeloproliferation characterized by immature megakaryoblasts that occurs in 5–10% of neonates with Down syndrome (DS). Although TAM regresses spontaneously in most patients, approximately 20%
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::906ce48803dff2211ce4b46dc0cdd38f
https://pubmed.ncbi.nlm.nih.gov/33394336
https://pubmed.ncbi.nlm.nih.gov/33394336