Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Manabu Sasaguri"'
Publikováno v:
Journal of the American Society of Nephrology. 12:29-36
Renal sodium handling is important for regulating BP, and renal dopamine and adenosine play an important role in renal sodium handling, however the interaction of these hormones in the kidney was not clarified. In in vivo experiments, adenosine signi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::738b056d49c1c64b52dfcfe1b5eb87dd
https://doi.org/10.1681/asn.v12129
https://doi.org/10.1681/asn.v12129
Autor:
Manabu Sasaguri, Kazuyuki Shirai, Kikuo Arakawa, Takemasa Matsumoto, Keita Noda, Emiko Tsuji, Yuji Tsuji
Publikováno v:
Hypertension Research. 23:709-712
A 53-year-old male was found to have hypertension caused by the significant secretion of renin from an atrophic left kidney. He had undergone extracorporeal shock-wave lithotripsy (ESWL) for left renal lithiasis 11 years previously. A renal dynamic s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::713e7ec5fc34cc66ac3ced4c01b21131
https://doi.org/10.1291/hypres.23.709
https://doi.org/10.1291/hypres.23.709
Autor:
Munehito Ideishi, Emiko Tsuji, Akio Kinoshita, Takaaki Sakai, Kikuo Arakawa, Manabu Sasaguri, Hirokazu Maeda, Keita Noda, Manabu Koga
Publikováno v:
Hypertension Research. 23:511-519
We have previously shown that both renal dopamine (DA) and kallikrein-kinin systems are activated by exercise in mild hypertensives. We aimed to confirm the effects of exercise on the renal DA system and the stimulatory effects of DA on the renal kal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed17098ae7bc69ef3eaa9f66604e8abd
https://doi.org/10.1291/hypres.23.511
https://doi.org/10.1291/hypres.23.511
Autor:
Tadashi Tashiro, Noriyuki Sakata, Michio Kimura, Yoshinari Uehara, Hidenori Urata, Munehito Ideishi, Manabu Sasaguri, Kikuo Arakawa
Publikováno v:
Hypertension. 35:55-60
Abstract —Apart from ACE, various angiotensin II (Ang II)–forming serine proteinases (eg, chymase, kallikrein, and cathepsin G) are known to exist in human tissues, but their clinical significance or the regulatory mechanisms that control their a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df08d35df35bd96a2362241c30ddd0bc
https://doi.org/10.1161/01.hyp.35.1.55
https://doi.org/10.1161/01.hyp.35.1.55
Autor:
Akio Kinoshita, Kikuo Arakawa, Keita Noda, Emiko Tsuji, Shigenori Ogata, Munehito Ideishi, Manabu Sasaguri, Manabu Koga
Publikováno v:
Immunopharmacology. 44:15-19
We previously purified a kallikrein-like enzyme from the dog heart and demonstrated that it is not only able to form kinins but can also convert angiotensin (Ang) I to Ang II. The aim of the present study was to clarify the structure and tissue local
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22c232fcbef4b9bf377b35115c36a510
https://doi.org/10.1016/s0162-3109(99)00106-x
https://doi.org/10.1016/s0162-3109(99)00106-x
Autor:
Masahiro Kikuchi, Junji Suzumiya, Munehito Ideishi, Hidenori Urata, Kikuo Arakawa, Manabu Sasaguri, Akio Kinoshita, Makoto Ihara
Publikováno v:
Hypertension. 33:1399-1405
Abstract —Locally formed angiotensin II (Ang II) and mast cells may participate in the development of atherosclerosis. Chymase, which originates from mast cells, is the major Ang II–forming enzyme in the human heart and aorta in vitro. The aim of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa77d6a702505d26be57210ca3a23ede
https://doi.org/10.1161/01.hyp.33.6.1399
https://doi.org/10.1161/01.hyp.33.6.1399
Publikováno v:
Hypertension. 32:514-520
Abstract —Angiotensin (Ang) II plays an important role in cardiovascular homeostasis, not only in the systemic circulation but also at the tissue level, and is involved in the remodeling of the heart and vasculature under pathological conditions. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::370d6bba337c4ebbf78ddccf221ba20b
https://doi.org/10.1161/01.hyp.32.3.514
https://doi.org/10.1161/01.hyp.32.3.514
Autor:
Manabu Sasaguri, E Tashiro, Manabu Koga, Kikuo Arakawa, Shin-ichiro Miura, Munehito Ideishi, Akio Kinoshita
Publikováno v:
Journal of Human Hypertension. 12:455-461
To clarify the ability of clinical and laboratory parameters to reflect target organ damage, especially left ventricular hypertrophy (LVH), we investigated which of these parameters might correlate to LVH as determined by electrocardiographic voltage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de87cc73e4678fc22cb05e6264223cb1
https://doi.org/10.1038/sj.jhh.1000612
https://doi.org/10.1038/sj.jhh.1000612
Autor:
Shigenori Ogata, Hirokazu Maeda, Manabu Sasaguri, Keita Noda, Akio Kinoshita, Kikuo Arakawa, Emiko Tsuji, Munehito Ideishi
Publikováno v:
Journal of Hypertension. 15:675-682
Objective To purify and characterize a kinin-forming enzyme in the dog heart and to examine the ability of this enzyme to generate angiotensin (Ang) II from Ang I. Methods The enzyme was isolated from heart homogenate using a diethylaminoethyl-Sephar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0e778e18927cd4787200ffa5f372539
https://doi.org/10.1097/00004872-199715060-00014
https://doi.org/10.1097/00004872-199715060-00014
Publikováno v:
Hypertension Research. 17:253-258
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80761e6d1e3283fa98f39742a76e60fe
https://doi.org/10.1291/hypres.17.253
https://doi.org/10.1291/hypres.17.253