Zobrazeno 1 - 10
of 198
pro vyhledávání: '"Manabu Sakai"'
Publikováno v:
FEBS Open Bio, Vol 12, Iss 2, Pp 460-469 (2022)
The transcription factor, hypoxia‐inducible factor‐1α (HIF‐1α), has previously been shown to upregulate the expression of hypoxia‐related genes, including erythropoietin (EPO). However, the role of hypoxia‐inducible factor‐1α in morpho
Externí odkaz:
https://doaj.org/article/3267a8e1d1e048d9b270982c40120f54
Publikováno v:
BMC Veterinary Research, Vol 17, Iss 1, Pp 1-8 (2021)
Abstract Background Lobular dissecting hepatitis (LDH) is a rare form of canine liver cirrhosis that may be accompanied by portal hypertension in American Cocker Spaniels. In human patients with liver cirrhosis, portal vein thrombosis (PVT) is a comm
Externí odkaz:
https://doaj.org/article/40a37037554245c7a9e5b15af212559a
Autor:
Yumi Sakamoto, Kumiko Ishigaki, Chieko Ishikawa, Tomohiro Nakayama, Kazushi Asano, Manabu Sakai
Publikováno v:
BMC Veterinary Research, Vol 16, Iss 1, Pp 1-7 (2020)
Abstract Background Portal vein thrombosis (PVT) is a rare presentation in dogs with protein-losing enteropathy (PLE). Rivaroxaban, an oral, selective, direct factor Xa inhibitor, has not been reported to be administrated for canine PVT and the effec
Externí odkaz:
https://doaj.org/article/c72b977ce24242b680ec8a01d32c5b1d
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 34, Iss 1, Pp 139-144 (2020)
Abstract Background The renin‐angiotensin‐aldosterone system (RAAS) is activated in humans with portal hypertension (PH) associated with liver disease. However, involvement of RAAS in dogs with intrahepatic PH is not clear. Objective To measure p
Externí odkaz:
https://doaj.org/article/780f32dfb415453aa4fca8b417a445a8
Autor:
Manabu Sakai, Bart Spee, Guy C. M. Grinwis, Louis C. Penning, Monique E. vanWolferen, Luc J. W. van derLaan, Hille Fieten
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 33, Iss 1, Pp 151-157 (2019)
Background Chronic hepatitis (CH) in dogs is common and has the tendency to progress to liver cirrhosis (LC). Circulating microRNAs might have the potential as markers for disease progression. Objectives To investigate whether concentration of specif
Externí odkaz:
https://doaj.org/article/b3d818b5ca1a44fabe4546525ba47d27
Autor:
Nanako Kitanaka, Rei Nakano, Manabu Sakai, Taku Kitanaka, Shinichi Namba, Tadayoshi Konno, Tomohiro Nakayama, Hiroshi Sugiya
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0222869 (2019)
Matrix metalloproteinases (MMPs) play a pivotal role in tissue remodeling by degrading the extracellular matrix (ECM) components. This mechanism is implicated in a variety of physiological and pathological cellular processes including wound healing.
Externí odkaz:
https://doaj.org/article/8124cdb2fe9942849fde0fa38af00fe9
Publikováno v:
Journal of King Saud University: Computer and Information Sciences, Vol 27, Iss 2, Pp 140-146 (2015)
In this paper we derive admissible curvature continuous areas for monotonically increasing curvature continuous smooth curve by using a single Pythagorean hodograph (PH) quintic polynomial of G2 contact matching Hermite end conditions. Curves with mo
Externí odkaz:
https://doaj.org/article/a7bd06519f13438782aae42f5b21e47b
Autor:
Aya Obana-Koshino, Hitomi Ono, Jiro Miura, Manabu Sakai, Hitoshi Uchida, Wataru Nakamura, Kanji Nohara, Yusuke Maruyama, Atsuhiko Hattori, Takayoshi Sakai
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0119960 (2015)
Many organs, including salivary glands, lung, and kidney, are formed by epithelial branching during embryonic development. Branching morphogenesis occurs via either local outgrowths or the formation of clefts that subdivide epithelia into buds. This
Externí odkaz:
https://doaj.org/article/9a57d637e08a4a9790893934ec02870b
Autor:
Zulfiqar Habib, Manabu Sakai
Publikováno v:
Mathematical Modelling and Analysis, Vol 17, Iss 2 (2012)
This paper considers how to smooth three kinds of G 1 biarc models, the C-, S-, and J-shaped transitions, by replacing their parts with spiral segments using a single cubic Bézier curve. Arc spline is smoothed to G 2continuity. Use of a single curve
Externí odkaz:
https://doaj.org/article/ef04f0fdda0c4df6ac5ec5fadabd9adc
Autor:
Riaz A. Usmani, Manabu Sakai
Publikováno v:
International Journal of Mathematics and Mathematical Sciences, Vol 10, Iss 3, Pp 525-529 (1987)
This paper describes some new finite difference methods of order 2 and 4 for computing eigenvalues of a two-point boundary value problem associated with a fourth order differential equation of the form (py″)′′+(q−λr)y=0. Numerical results
Externí odkaz:
https://doaj.org/article/406c2a5953644e1690fa5a5396052bf4