Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Manabu Inobe"'
Publikováno v:
Asian Pacific Journal of Allergy & Immunology; Sep2024, Vol. 42 Issue 3, p298-304, 7p
Publikováno v:
Asian Pacific Journal of Allergy and Immunology.
Background Cyclosporin A (CSA) and tacrolimus (TAC) suppress T-cell activation and subsequent proliferation by inhibiting calcineurin. Though they have the same target, CSA and TAC have quite different molecular structures, indicating quantitative an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c653f14f7c5c871edc6d5110bad613a
https://doi.org/10.12932/ap-270820-0949
https://doi.org/10.12932/ap-270820-0949
Publikováno v:
Microbiology and Immunology. 61:168-175
T-cell population consists of two major subsets, CD4+ T cells and CD8+ T cells, which can be distinguished by the expression of CD4 or CD8 molecules, respectively. Although they play quite different roles in the immune system, many of their basic cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60be7c903833b2c95f349734ef9b1906
https://doi.org/10.1111/1348-0421.12479
https://doi.org/10.1111/1348-0421.12479
Autor:
Chika Yasuoka, Manabu Inobe, Yoshiaki Ando, Takuya Mishima, Tsukasa Matsunaga, Toshimitsu Uede, Takuya Ikematsu
Publikováno v:
In Vitro Cellular and Developmental Biology - Animal. 50(4):313-320
T cell activation is regulated by two distinct signals, signals one and two. Concanavalin A (ConA) is an antigen-independent mitogen and functions as signal one inducer, leading T cells to polyclonal proliferation. CD28 is known to be one of major co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94628b21a6012ed72cf88dd13140697a
http://hdl.handle.net/2297/36268
http://hdl.handle.net/2297/36268
Publikováno v:
Cellular & Molecular Biology Letters
Peripheral T cells are in G0 phase and do not proliferate. When they encounter an antigen, they enter the cell cycle and proliferate in order to initiate an active immune response. Here, we have determined the first two cell cycle times of a leading
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57b2ac3047dd5ceaedb6576bcb27dc18
http://hdl.handle.net/2297/40602
http://hdl.handle.net/2297/40602
Autor:
Takuya, Mishima, Shotaro, Fukaya, Shoko, Toda, Yoshiaki, Ando, Tsukasa, Matsunaga, Manabu, Inobe
Publikováno v:
Microbiology and immunology. 61(5)
T-cell population consists of two major subsets, CD4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e05b86cd5a0801ee24e0071daff8af22
https://pubmed.ncbi.nlm.nih.gov/28370382
https://pubmed.ncbi.nlm.nih.gov/28370382
Autor:
Tsukasa Matsunaga, Megumi Matsumoto, Kuniyoshi Iwabuchi, Kanji Ishizaki, Mayumi Imura, Toshio Mori, Manabu Inobe, Mizuho Hasegawa, Takayasu Date, Kie Yaginuma, Ai Igarashi, Katsumi Yamashita
Publikováno v:
Journal of Cell Science. 120:1104-1112
Human histone H2AX is rapidly phosphorylated on serine 139 in response to DNA double-strand breaks and plays a crucial role in tethering the factors involved in DNA repair and damage signaling. Replication stress caused by hydroxyurea or UV also init
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22ecd8d1a56a208c5b39d85a7fefcb4d
https://doi.org/10.1242/jcs.03391
https://doi.org/10.1242/jcs.03391
Autor:
Go Haraguchi, Manabu Inobe, Hisanori Kosuge, Toshimitsu Uede, Yasuhiro Maejima, Jun-ichi Suzuki, Noritaka Koga, Mitsuaki Isobe
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 26:2660-2665
Objective— Proliferation and migration of smooth muscle cells (SMCs) and migration and accumulation of monocytes and T cells are landmark events in the development of arteriosclerosis. SMC proliferation in the intima induces interruption of blood f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::affb937f8f280033ae55bbcb2da361a5
https://doi.org/10.1161/01.atv.0000245805.52081.ca
https://doi.org/10.1161/01.atv.0000245805.52081.ca
Autor:
Kenji Sano, Hiroshi Imamura, Masafumi Takahashi, Mitsuaki Isobe, Manabu Inobe, Megumi Takehara, Toshimitsu Uede, Atsushi Izawa, Jun-ichi Suzuki, Uichi Ikeda
Publikováno v:
Cardiovascular Research. 69:289-297
Objective: Transfer of the CTLA4IgG gene induces long-term and high levels of CTLA4IgG expression, which can result in generalized immunosuppression. In this study, we utilized Cre/loxP-mediated on–off switch recombination to eliminate transgene ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d715fad46990143f1ced1d41a069eab5
https://doi.org/10.1016/j.cardiores.2005.07.021
https://doi.org/10.1016/j.cardiores.2005.07.021
Autor:
Atsushi Imai, Kenichiro Yamashita, Nan Hua, Manabu Inobe, Taro Masunaga, Satoru Todo, Tadaaki Miyazaki, Taku Hashimoto, Toshimitsu Uede, Hideyasu Sakihama
Publikováno v:
Transplantation. 80:1614-1622
Background. We previously reported that adenovirus mediated CD40Ig gene therapy (AdCD40Ig) induced long-term acceptance of fully allogeneic rat cardiac allografts, however, the underlying mechanism has not been fully clarified. To address this we hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97ee8d7d31c2eb825585d508ae487fb5
https://doi.org/10.1097/01.tp.0000181093.50141.6c
https://doi.org/10.1097/01.tp.0000181093.50141.6c