Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Manabu Sugai"'
Autor:
Sayaka Mishima, Katsu Takahashi, Honoka Kiso, Akiko Murashima-Suginami, Yoshihito Tokita, Jun-Ichiro Jo, Ryuji Uozumi, Yukiko Nambu, Boyen Huang, Hidemitsu Harada, Toshihisa Komori, Manabu Sugai, Yasuhiko Tabata, Kazuhisa Bessho
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Runt-related transcription factor 2 (Runx2)-deficient mice can be used to model congenital tooth agenesis in humans. Conversely, uterine sensitization-associated gene-1 (Usag-1)-deficient mice exhibit supernumerary tooth formation. Arrested
Externí odkaz:
https://doaj.org/article/b69b2500ef85490687eba3c4e049a2f7
Autor:
Katsu Takahashi, Honoka Kiso, Akiko Murashima-Suginami, Yoshihito Tokita, Manabu Sugai, Yasuhiko Tabata, Kazuhisa Bessho
Publikováno v:
Inflammation and Regeneration, Vol 40, Iss 1, Pp 1-9 (2020)
Abstract Analysis of various genetically modified mice, with supernumerary teeth, has revealed the following two intrinsic molecular mechanisms that increase the number of teeth. One plausible explanation for supernumerary tooth formation is the resc
Externí odkaz:
https://doaj.org/article/6df984da5359472497a0e5d6d7596fe5
Autor:
Kyoko Biyajima, Fumihiko Kakizaki, Xiaodong Shen, Kentaro Mori, Manabu Sugai, M. Mark Taketo, Yoshifumi Yokota
Publikováno v:
Biology Open, Vol 4, Iss 8, Pp 993-1001 (2015)
The expression level of inhibitor of DNA binding 2 (Id2) is increased in colorectal carcinomas and is positively correlated with poor prognosis. However, the functional significance of Id2 in intestinal tumorigenesis has not been fully defined using
Externí odkaz:
https://doaj.org/article/2ca39883062a4a53b776c829f945abec
Autor:
Yumiko Togo, Katsu Takahashi, Kazuyuki Saito, Honoka Kiso, Hiroko Tsukamoto, Boyen Huang, Motoko Yanagita, Manabu Sugai, Hidemitsu Harada, Toshihisa Komori, Akira Shimizu, Mary MacDougall, Kazuhisa Bessho
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0161067 (2016)
Supernumerary teeth and tooth agenesis are common morphological anomalies in humans. We previously obtained evidence that supernumerary maxillary incisors form as a result of the successive development of the rudimentary maxillary incisor tooth germ
Externí odkaz:
https://doaj.org/article/076c04ac79814de298e9e3c3c430d045
Autor:
Yoshihito Tokita, Yasuhiko Tabata, Kazuhisa Bessho, Akiko Murashima-Suginami, Manabu Sugai, Honoka Kiso, Katsu Takahashi
Publikováno v:
Inflammation and Regeneration, Vol 40, Iss 1, Pp 1-9 (2020)
Inflammation and Regeneration
Inflammation and Regeneration
Analysis of various genetically modified mice, with supernumerary teeth, has revealed the following two intrinsic molecular mechanisms that increase the number of teeth. One plausible explanation for supernumerary tooth formation is the rescue of too
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed696d140be0b47593d0aac108b27eec
http://link.springer.com/article/10.1186/s41232-020-00130-x
http://link.springer.com/article/10.1186/s41232-020-00130-x
Autor:
Akari Nitta, Ayumi Igarashi, Koji Aoki, Takashi Ueno, Isei Tanida, Yasuyo Deyama, Kazuya Hori, Manabu Sugai, Eiki Kominami
Publikováno v:
Biochemical and Biophysical Research Communications. 508:521-526
Autophagy, a system for the bulk degradation of intracellular components, is essential for homeostasis and the healthy physiology and development of cells and tissues. Its deregulation is associated with human disease. Thus, methods to modulate autop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91e6f0719f26dbeb229dc7747bca91f5
https://doi.org/10.1016/j.bbrc.2018.11.158
https://doi.org/10.1016/j.bbrc.2018.11.158
Autor:
Honoka Kiso, Katsu Takahashi, Kazuyuki Saito, Yumiko Togo, Hiroko Tsukamoto, Boyen Huang, Manabu Sugai, Akira Shimizu, Yasuhiko Tabata, Aris N Economides, Harold C Slavkin, Kazuhisa Bessho
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e96938 (2014)
Bone morphogenetic proteins (BMPs) are highly conserved signaling molecules that are part of the transforming growth factor (TGF)-beta superfamily, and function in the patterning and morphogenesis of many organs including development of the dentition
Externí odkaz:
https://doaj.org/article/0c57dd312ca5439da3d15ee07a03feff
Autor:
Honoka Kiso, Junichi Takagi, Katsu Takahashi, Yukiko Nambu, Yasuhiko Tabata, Kazuhisa Bessho, Ryuji Uozumi, Yoshihito Tokita, E. Mihara, Akiko Murashima-Suginami, Manabu Sugai
Publikováno v:
Science Advances
Uterine sensitization–associated gene-1 (USAG-1) deficiency leads to enhanced bone morphogenetic protein (BMP) signaling, leading to supernumerary teeth formation. Furthermore, antibodies interfering with binding of USAG-1 to BMP, but not lipoprote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1208091ea96c6506012f82105b2e01db
https://doi.org/10.1126/sciadv.abf1798
https://doi.org/10.1126/sciadv.abf1798
Autor:
Kazuhisa Bessho, Katsu Takahashi, Hironori Haga, Manabu Sugai, Honoka Kiso, Kazumasa Nakao, Akira Shimizu, Masayuki Ikeno, Noriaki Koyama, Yu Isobe
Publikováno v:
Archives of Oral Biology. 93:133-140
Objective Fibrous dysplasia (FD) is a benign bone disease characterized by fibro-osseous lesions. FD is caused by somatic mutations in the gene, guanine nucleotide-binding protein, alpha stimulating activity polypeptide 1 (GNAS), which encodes the G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e90590ed2a0fe45ec5986bfd3edf6a37
https://doi.org/10.1016/j.archoralbio.2018.05.018
https://doi.org/10.1016/j.archoralbio.2018.05.018
Autor:
Katsu Takahashi, Masaki Nagata, Toshihisa Komori, Honoka Kiso, Masato Asai, Akira Shimizu, Yoshihito Tokita, Sayaka Mishima, Mary MacDougall, Hiroko Tsukamoto, Kazuhisa Bessho, Manabu Sugai, Boyen Huang, Machiko Iida, Yumiko Togo, Kazuyuki Saito, Masakazu Asahara, Hidemitsu Harada
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Charles Sturt University
Charles Sturt University
Adult Cebpb KO mice incisors present amelogenin-positive epithelium pearls, enamel and dentin allopathic hyperplasia, fewer Sox2-positive cells in labial cervical loop epitheliums, and reduced Sox2 expression in enamel epithelial stem cells. Thus, Ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0120229ef1a0774ded2e22c9285b67e
http://link.springer.com/article/10.1038/s41598-018-23515-y
http://link.springer.com/article/10.1038/s41598-018-23515-y