Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Mana Azumi"'
Publikováno v:
Journal of Pharmacological Sciences, Vol 150, Iss 4, Pp 259-266 (2022)
Uterine leiomyosarcoma is an aggressive soft tissue tumor. Stathmin, a phosphoprotein that modulates microtubule dynamics, is highly expressed in many malignancies including leiomyosarcoma. The microtubule-depolymerizing agent eribulin has been recen
Externí odkaz:
https://doaj.org/article/22ec3201c253415f9d8adb80b39c5e4e
Publikováno v:
Journal of Pharmacological Sciences, Vol 150, Iss 4, Pp 267-274 (2022)
The pathogenesis of hypertensive disorder of pregnancy (HDP), which affects about 10% of pregnant women, is still incompletely understood. Our previous study showed that endoplasmic reticulum (ER) stress influences high-temperature requirement A seri
Externí odkaz:
https://doaj.org/article/661b0f57eb7d4142a7e3254510f02246
Autor:
Atsuya Tsuru, Mikihiro Yoshie, Ryo Yonekawa, Junya Kojima, Mana Azumi, Kazuya Kusama, Hirotaka Nishi, Kazuhiro Tamura
Publikováno v:
Reproductive Medicine, Vol 3, Iss 2, Pp 189-200 (2022)
Human endometrial stromal cells (ESCs) differentiate into decidual cells for embryo implantation during the mid-secretory phase of the menstrual cycle. Decidualization is characterized by enhanced production of insulin-like growth factor-binding prot
Externí odkaz:
https://doaj.org/article/3ce5958daf0349d390ef438a92cd559a
Autor:
Mikihiro Yoshie, Kensuke Ohishi, Gen Ishikawa, Atsuya Tsuru, Kazuya Kusama, Mana Azumi, Kazuhiro Tamura
Publikováno v:
Reproductive Medicine and Biology, Vol 22, Iss 1, Pp n/a-n/a (2023)
Abstract Purpose Extravillous trophoblasts (EVTs) invade the endometrium to establish a fetomaternal interaction during pregnancy. Epidermal growth factor (EGF) and heparin‐binding EGF‐like growth factor (HB‐EGF) stimulate EVT invasion by bindi
Externí odkaz:
https://doaj.org/article/b307b5b2ac40435e9468042afcd2065e
Autor:
Kazuya Kusama, Ayaka Satoyoshi, Mana Azumi, Mikihiro Yoshie, Junya Kojima, Yumi Mizuno, Masanori Ono, Hirotaka Nishi, Takeshi Kajihara, Kazuhiro Tamura
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Endometriosis is characterized by the presence of inflamed and fibrotic endometrial tissue outside the uterine cavity. Previously, we found decreased SERPINA1 (alpha-1 antitrypsin) expression in endometriosis-like lesions in a mouse model of endometr
Externí odkaz:
https://doaj.org/article/ec8aa575c7554b398e1ce4d74fa682ed
Publikováno v:
Pharmacology Research & Perspectives, Vol 9, Iss 4, Pp n/a-n/a (2021)
Abstract Stathmin, a phosphoprotein that modulates microtubule dynamics, is highly expressed in breast cancer cells. Eribulin, a microtubule‐depolymerizing agent, is used to treat patients with advanced breast cancer. However, the detailed mechanis
Externí odkaz:
https://doaj.org/article/7faca68fa7e8416dae1e934564b73aa5
Autor:
Atsuya Tsuru, Mikihiro Yoshie, Junya Kojima, Ryo Yonekawa, Mana Azumi, Kazuya Kusama, Hirotaka Nishi, Kazuhiro Tamura
Publikováno v:
Biomolecules, Vol 12, Iss 8, p 1046 (2022)
The appropriate differentiation of endometrial stromal cells (ESCs) into decidual cells is required for embryo implantation and subsequent placentation into humans. Decidualization is accompanied by the appearance of senescent-like cells. We recently
Externí odkaz:
https://doaj.org/article/4396b67d094f4000875541940a011daa
Autor:
Atsuya Tsuru, Mikihiro Yoshie, Mei Suzuki, Hiroki Mochizuki, Satoshi Kametaka, Takako Ohmaru-Nakanishi, Mana Azumi, Kazuya Kusama, Kiyoko Kato, Kazuhiro Tamura
Publikováno v:
Journal of Endocrinology; Feb2024, Vol. 260 Issue 2, p16-27, 12p
Publikováno v:
Biochemical and Biophysical Research Communications. 571:174-180
Decidualization - the differentiation of endometrial stromal cells (ESCs) into decidual cells - is a crucial step for successful embryo implantation and placentation that is initiated in the secretory phase of the menstrual cycle. During decidualizat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e3d755cd851a855eac7aa56a5ff4b79
https://doi.org/10.1016/j.bbrc.2021.07.075
https://doi.org/10.1016/j.bbrc.2021.07.075
Publikováno v:
Biologicalpharmaceutical bulletin. 45(11)
Eribulin, an inhibitor of microtubule dynamics, is used for treating breast cancers and sarcomas. The microtubule-destabilizing protein stathmin may modulate the antiproliferative activity of eribulin on breast cancer cells and leiomyosarcoma cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e0683e8da61dbb26179382339f16720
https://pubmed.ncbi.nlm.nih.gov/36328498
https://pubmed.ncbi.nlm.nih.gov/36328498