Zobrazeno 1 - 10
of 246
pro vyhledávání: '"Man-sau Wong"'
Publikováno v:
Biomedical Journal, Vol 47, Iss 4, Pp 100685- (2024)
Among the various targeting ligands for drug delivery, aptamers have attracted much interest in recent years because of their smaller size compared to antibodies, ease of modification, and better batch-to-batch consistency. In addition, aptamers can
Externí odkaz:
https://doaj.org/article/eddc534adcdb4f008f185321d8036afd
Autor:
Wen-Xuan Yu, Christina Chui-Wa Poon, Li-Ping Zhou, Ka-Ying Wong, Si-Si Cao, Chung-Yan Lam, Wayne Yuk-wai Lee, Man-Sau Wong
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 173, Iss , Pp 116402- (2024)
Oleanolic acid (OA) is previously shown to exert bone protective effects in aged animals. However, its role in regulating osteoblastic vitamin D bioactivation, which is one of major causes of age-related bone loss, remains unclear. Our results reveal
Externí odkaz:
https://doaj.org/article/341430c094ef4707b4dc8792dd31dc4d
Autor:
Vicky Wai-ki Chan, Joson Hao-shen Zhou, Liz Li, Michael Tsz-hin Tse, Jane Jia You, Man-sau Wong, Justina Yat-wa Liu, Kenneth Ka-hei Lo
Publikováno v:
Nutrients, Vol 16, Iss 8, p 1132 (2024)
Changes in an individual’s digestive system, hormones, senses of smell and taste, and energy requirement accompanying aging could lead to impaired appetite, but older adults may not notice their risk of nutrient deficiency. When assessing the dieta
Externí odkaz:
https://doaj.org/article/4b77a8276d3b48c6b7c2898fc45b646b
Autor:
Wen-Xuan Yu, Hok-Him Tang, Jun-Jie Ye, Hui-Hui Xiao, Chung-Yan Lam, Tim-Fat Shum, Zhi-Kang Sun, Yuan-Zhen Li, Xin-Yu Zang, Wen-Chao Du, Jian-Ping Zhang, Tsz-Hung Kong, Li-Ping Zhou, Jia-Chi Chiou, Chun-Fai Kung, Kam-Wah Mok, Jing Hu, Man-Sau Wong
Publikováno v:
Molecules, Vol 28, Iss 15, p 5742 (2023)
Secoisolariciresinol (SECO) is one of the major lignans occurring in various grains, seeds, fruits, and vegetables. The gut microbiota plays an important role in the biotransformation of dietary lignans into enterolignans, which might exhibit more po
Externí odkaz:
https://doaj.org/article/8dacd9cdd0004fb998b61c380a59cedb
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
IntroductionIn postmenopausal women, vitamin D deficiency (as defined by the circulating level of 25(OH)D being below 20 ng/ml (50 nmol/L)) is a regular occurrence. The effect of vitamin D supplementation on the muscle function of postmenopausal wome
Externí odkaz:
https://doaj.org/article/9c554276794949978c38cf4896e6e31e
Autor:
Liping Zhou, Ka-Ying Wong, Christina Chui-Wa Poon, Wenxuan Yu, Huihui Xiao, Chi-On Chan, Daniel Kam-Wah Mok, Man-Sau Wong
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Our previous study demonstrated that the bone protective actions of herbal medicine Rhizoma Drynariae (Gusuibu, RD) were mainly mediated by flavonoid phytoestrogens via estrogen receptors, raising concerns about the safety of using RD as it may induc
Externí odkaz:
https://doaj.org/article/4daefdc4322a4ed9ad2fd8e538e7ca2e
Autor:
Zuo-Cheng Qiu, Feng-Xiang Zhang, Xue-Ling Hu, Yang-Yang Zhang, Zi-Ling Tang, Jie Zhang, Li Yang, Man-Sau Wong, Jia-Xu Chen, Hui-Hui Xiao
Publikováno v:
Molecules, Vol 27, Iss 22, p 7811 (2022)
Postmenopausal osteoporosis is a significant threat to human health globally. Genistein, a soy-derived isoflavone, is regarded as a promising anti-osteoporosis drug with the effects of promoting osteoblastogenesis and suppressing osteoclastogenesis.
Externí odkaz:
https://doaj.org/article/592963016e4e4d949ee3204f698e3c0c
Autor:
Hui-Hui Xiao, Yu-Xin Zhu, Lu Lu, Li-Ping Zhou, Christina Chui-Wa Poon, Chi-On Chan, Li-Jing Wang, Sisi Cao, Wen-Xuan Yu, Ka-Ying Wong, Daniel Kam-Wah Mok, Man-Sau Wong
Publikováno v:
Nutrients, Vol 14, Iss 22, p 4718 (2022)
Our previous study revealed that the bone anabolic effects of the lignan-rich fraction (SWCA) from Sambucus williamsii Hance was involved in modulating the metabolism of tryptophan in vivo and inhibiting serotonin (5-HT) synthesis in vitro. This stud
Externí odkaz:
https://doaj.org/article/ee7cbae4a5794855b9a394ebdef89061
Autor:
Hui-Hui Xiao, Lu Lu, Christina Chui-Wa Poon, Chi-On Chan, Li-Jing Wang, Yu-Xin Zhu, Li-Ping Zhou, Sisi Cao, Wen-Xuan Yu, Ka Ying Wong, Daniel Kam-Wah Mok, Man-Sau Wong
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 137, Iss , Pp 111372- (2021)
Menopausal women are susceptible to have high risk of cardiovascular diseases, type II diabetes and osteoporosis due to the metabolic disorder caused by estrogen deficiency. Accumulating evidence supports that gut microbiota is a key regulator of met
Externí odkaz:
https://doaj.org/article/78054643b94845a5a04f56723fb234d9
Autor:
Quan-Gui Gao, Li-Ping Zhou, Vien Hoi-Yi Lee, Hoi-Yi Chan, Cornelia Wing-Yin Man, Man-Sau Wong
Publikováno v:
Journal of Ginseng Research, Vol 43, Iss 4, Pp 527-538 (2019)
Background: Ginsenoside Rg1 was shown to exert ligand-independent activation of estrogen receptor (ER) via mitogen-activated protein kinase–mediated pathway. Our study aimed to delineate the mechanisms by which Rg1 activates the rapid ER signaling
Externí odkaz:
https://doaj.org/article/11a71ab9d16645aa826959ad145575ac