Alisertib Induces Cell Cycle Arrest, Apoptosis, Autophagy and Suppresses EMT in HT29 and Caco-2 Cells

Autor: Bao-Jun Ren, Zhi-Wei Zhou, Da-Jian Zhu, Yong-Le Ju, Jin-Hao Wu, Man-Zhao Ouyang, Xiao-Wu Chen, Shu-Feng Zhou

Publikováno v: International Journal of Molecular Sciences, Vol 17, Iss 1, p 41 (2015)

Colorectal cancer (CRC) is one of the most common malignancies worldwide with substantial mortality and morbidity. Alisertib (ALS) is a selective Aurora kinase A (AURKA) inhibitor with unclear effect and molecular interactome on CRC. This study aimed

Externí odkaz: https://doaj.org/article/1b99ae93c063458d9c0c995047729562

Twist1 is a potential prognostic marker for colorectal cancer and associated with chemoresistance

Autor: Da-Jian, Zhu, Xiao-Wu, Chen, Wei-Jie, Zhang, Jia-Zhi, Wang, Man-Zhao, Ouyang, Qiang, Zhong, Chang-Chun, Liu

Publikováno v: American journal of cancer research. 5(6)

Twist1 is a highly conserved basic helix-loophelix transcription factor, and has been shown to play an important role in carcinogenesis of many tumors including colorectal cancer (CRC). Here we aimed to investigate the role of Twist1 in the clinical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e1a1195827c906855c8b475267af35e8
https://pubmed.ncbi.nlm.nih.gov/26269759

Alisertib Induces Cell Cycle Arrest, Apoptosis, Autophagy and Suppresses EMT in HT29 and Caco-2 Cells.

Autor: Bao-Jun Ren, Zhi-Wei Zhou, Da-Jian Zhu, Yong-Le Ju, Jin-Hao Wu, Man-Zhao Ouyang, Xiao-Wu Chen, Shu-Feng Zhou

Publikováno v: International Journal of Molecular Sciences; 2016, Vol. 17 Issue 1, p41, 34p, 8 Color Photographs, 4 Black and White Photographs, 1 Diagram, 8 Charts, 1 Graph