Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Man-Gen Song"'
Publikováno v:
Biochemical and biophysical research communications. 526(2)
The post-transcriptional regulation of gene expression plays an important role in many essential biological processes. The RNA decapping enzyme Dcp2 is a crucial enzyme involved in RNA degradation. Dcp2 proteins are highly expressed in the testis and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::814b1feb50e5252a577d80b88fbfc8ac
https://pubmed.ncbi.nlm.nih.gov/32245620
https://pubmed.ncbi.nlm.nih.gov/32245620
Publikováno v:
RNA. 19:390-399
RNA decapping is an important contributor to gene expression and is a critical determinant of mRNA decay. The recent demonstration that mammalian cells harbor at least two distinct decapping enzymes that preferentially modulate a subset of mRNAs rais
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::965205521a93e1629a66c02b3add1fc2
https://doi.org/10.1261/rna.037309.112
https://doi.org/10.1261/rna.037309.112
Publikováno v:
Molecular and Cellular Biology. 32:1164-1172
The mammalian Dcp2 mRNA-decapping protein functions primarily on a subset of mRNAs in a transcript-specific manner. Here we show that Dcp2 is an important modulator of genes involved in the type I interferon (IFN) response, which is the initial line
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2da49c3840815394a513b999004d1ce
https://doi.org/10.1128/mcb.06328-11
https://doi.org/10.1128/mcb.06328-11
Publikováno v:
RNA (New York, N.Y.). 22(5)
Removal of the 5′-end 7-methylguanosine cap structure is a critical step in the highly regulated process of mRNA decay. The Nudix hydrolase, Dcp2, was identified as a first decapping enzyme and subsequently shown to preferentially modulate stabilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7f76ebb9a54a4903e293a6e5695ee98
https://pubmed.ncbi.nlm.nih.gov/26932476
https://pubmed.ncbi.nlm.nih.gov/26932476
Autor:
Man Gen Song, Megerditch Kiledjian
Publikováno v:
RNA. 13:2356-2365
Decapping is a critical step in the control of gene expression and is regulated by both positive and negativetransfactors. Less is known aboutciselements that promote decapping. In plants, following microRNA (miRNA)-directed cleavage of an mRNA, a ur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72ca9c8d55ea85a3847ffd19b3054055
https://doi.org/10.1261/rna.765807
https://doi.org/10.1261/rna.765807
Autor:
Lin-Ling Peng, Shu Xiao, Dong Li, Ai-Xia Dou, Guo-Qiang Chen, Zhu Chen, Pei-Min Jia, Man-Gen Song, Sai-Juan Chen, Hai-Qing Zhu, Jian-Hua Tong, Xiao-Rong Pan
Publikováno v:
Proceedings of the National Academy of Sciences. 103:16448-16453
TheRIG-Ggene, originally isolated from an acute promyelocytic leukemia cell line NB4, codes for a 60-kDa cytoplasmic protein that is induced byall-transretinoic acid (ATRA) treatment along with the induction of morphological differentiation of NB4 ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccb497c159f1d2f5cd812034723deb03
https://doi.org/10.1073/pnas.0607830103
https://doi.org/10.1073/pnas.0607830103
Autor:
Min Xu, Man-Gen Song, Shen-Meng Gao, Yuan-Shan Zhu, Yun Yu, Qiong Wang, Zhu Chen, Yu-Hong Zhou, Ke-Ming Du, Guo-Qiang Chen
Publikováno v:
Blood. 105:3714-3721
As a promising new class of anticancer drugs, camptothecins have advanced to the forefront of several areas of therapeutic and developmental chemotherapy. In the present study, we report that NSC606985, a rarely studied camptothecin analog, induces a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0acf6d259b889dea457d94bb018212f1
https://doi.org/10.1182/blood-2004-10-4011
https://doi.org/10.1182/blood-2004-10-4011
mRNA decapping is a crucial step in the regulation of mRNA stability and gene expression. Dcp2 is an mRNA decapping enzyme that has been widely studied. We recently reported the presence of a second mammalian cytoplasmic decapping enzyme, Nudt16. Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8edd6532f20317fce95a8dac5cd5ae8b
https://europepmc.org/articles/PMC3039142/
https://europepmc.org/articles/PMC3039142/
Publikováno v:
Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi. 28(12)
To investigate the biological function of RIG-G gene by establishing a cell line stably expressing RIG-G protein.Ectopic RIG-G gene was transfected into U937 cells by using Tet-off expression system. Changes before and after RIG-G expression were det
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1f2d5ccc095d54f90389c5d96337325d
https://pubmed.ncbi.nlm.nih.gov/18476588
https://pubmed.ncbi.nlm.nih.gov/18476588
mRNA decapping is a critical step in the control of mRNA stability and gene expression and is carried out by the Dcp2 decapping enzyme. Dcp2 is an RNA binding protein that must bind RNA in order to recognize the cap for hydrolysis. We demonstrate tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1c8f07eb675e6eaf7ec361cdbe0d9e4
https://europepmc.org/articles/PMC2223397/
https://europepmc.org/articles/PMC2223397/