Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Man Sung Co"'
Autor:
Man Sung Co, Keith O. Hodgson
Publikováno v:
Copper Proteins and Copper Enzymes ISBN: 9781351070904
Copper Proteins and Copper Enzymes
Copper Proteins and Copper Enzymes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::320a2be2da66250f3cc29ce668a2c050
https://doi.org/10.1201/9781351070904-4
https://doi.org/10.1201/9781351070904-4
Autor:
Hiroshi Nakao, Takashi Kawamura, Sharon Wei, Yuri Sakai, Tsuyoshi Kimura, Hattie Xu, Tae Takeda, Vasques Maximiliano, Yoh-Ichi Matsumoto, Man Sung Co, Shinobu Tani
Publikováno v:
Hybridoma and Hybridomics. 21:161-168
A murine monoclonal antibody (MAb), VTm1.1, specifically recognizing and neutralizing Shiga toxin 2 (Stx2), was obtained. To prevent a humoral response against murine antibody when used clinically, a humanized antibody was constructed by combining th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::762d3598a185892ea6beb75180f14045
https://doi.org/10.1089/153685902760173872
https://doi.org/10.1089/153685902760173872
Autor:
Lin Shan, Allen B. Edmundson, Man Sung Co, Cary L. Queen, Nicholas F. Landolfi, Archana B. Thakur, Paul A. Ramsland, Luke W. Guddat, Maximiliano Vasquez, Zhao-chang Fan, Benjamin Z. Goldsteen
Publikováno v:
Journal of Molecular Recognition. 12:19-32
The objective of this work is to compare the three-dimensional structures of "humanized" and mouse-human chimeric forms of a murine monoclonal antibody elicited against human gamma-interferon. It is also to provide structural explanations for the sma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83f4dd7c27424597f247349a22dd9534
https://doi.org/10.1002/(sici)1099-1352(199901/02)12:1<19::aid-jmr445>3.0.co
https://doi.org/10.1002/(sici)1099-1352(199901/02)12:1<19::aid-jmr445>3.0.co
Autor:
Cary Queen, Kevin J. Whaley, Richard A. Cone, Stuart S. Olmsted, Man Sung Co, David R. Russell, Larry Zeitlin, Brian J. Martinell, Vikram M. Paradkar, Thomas R. Moench
Publikováno v:
Nature Biotechnology. 16:1361-1364
The ability to produce monoclonal antibodies (Mabs) in plants offers the opportunity for the development of an inexpensive method of mucosal immunoprotection against sexually transmitted diseases. To investigate the suitability of plant-expressed Mab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::266894425dca24c7db79d4fe7500f793
https://doi.org/10.1038/4344
https://doi.org/10.1038/4344
Autor:
Shinya Yano, Seiji Kaku, Ken-ichi Suzuki, Toichi Takenaka, Yumiko Sakai, Koji Kawamura, Nicholas F. Landolfi, Tomihisa Kawasaki, Yasuhiko Masuho, Noboru Satoh, Man Sung Co
Publikováno v:
General Pharmacology: The Vascular System. 27:435-439
1. 1. The potential antiplatelet agent use of the whole molecule, F(ab) 2 and Fab fragments of humanized antiglycoprotein (GP) IIb/IIIa monoclonal antibody, hC4G1, were investigated in rhesus monkeys. 2. 2. Fab completely inhibited platelet aggregati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b8b9b8fc3b5b6e129ef0e9b709ec0cf
https://doi.org/10.1016/0306-3623(95)02057-8
https://doi.org/10.1016/0306-3623(95)02057-8
Autor:
Ronald D. Finn, David A. Scheinberg, Cary L. Queen, Martin C. Graham, Steven M. Larson, Man Sung Co, Chaitanya R. Divgi, Philip Caron, Michael A. Schwartz
Publikováno v:
Cancer. 73:1049-1056
Long-term survival rates of patients with acute myelogenous leukemia treated with intensive chemotherapy are 15-20%, despite efforts to develop new treatment strategies. Murine M195 ( 131 I-M195), an anti-CD33, immunoglobulin (Ig) G2a monoclonal anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa6fdf7d5dcd72838384d5a7b1359572
https://doi.org/10.1002/1097-0142(19940201)73:3+<1049::aid-cncr2820731344>3.0.co
https://doi.org/10.1002/1097-0142(19940201)73:3+<1049::aid-cncr2820731344>3.0.co
Autor:
W. Laird, Cary L. Queen, David A. Scheinberg, Man Sung Co, Philip Caron, Nevenka M. Avdalovic
Publikováno v:
The Journal of Experimental Medicine
Humanized IgG1 M195 (HuG1-M195), a complementarity determining region-grafted recombinant monoclonal antibody, is reactive with CD33, an antigen expressed on myelogenous leukemia cells. M195 is in use in trials for the therapy of acute myelogenous le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::298464ba5779f7555a9f323b87d98fe5
https://doi.org/10.1084/jem.176.4.1191
https://doi.org/10.1084/jem.176.4.1191
Autor:
Shauna H. Yuan, Jennifer Melrose, Paul R. Hinton, Nicholas F. Landolfi, Jennifer H Tan, Man Sung Co, Corine Klingbeil, Vladimir Vexler, Max Vasquez, Jon O. Nagy, Linda Roark, Ellen L. Berg, Cary L. Queen
Publikováno v:
Immunotechnology : an international journal of immunological engineering. 4(3-4)
Background: The participation of L-selectin in leukocyte recruitment during inflammation has suggested the use of L-selectin inhibitors as potential anti-inflammatory therapeutics. Blocking monoclonal antibodies could serve as such therapeutic agents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::accf947e911a95aa32ce2508c4d7e94b
https://pubmed.ncbi.nlm.nih.gov/10231094
https://pubmed.ncbi.nlm.nih.gov/10231094
Publikováno v:
Journal of pharmaceutical sciences. 83(12)
Characterization of monoclonal antibodies (MAbs) produced for therapeutic or diagnostic purposes increasingly includes an assessment of their carbohydrate content. Using high-performance anion exchange chromatography with pulsed amperometric detectio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2341231b4682a0c143dc103ea6e5def
https://pubmed.ncbi.nlm.nih.gov/7891293
https://pubmed.ncbi.nlm.nih.gov/7891293
Autor:
Man Sung Co, Kimberly Mcgraw, Max Vasquez, David A. Scheinberg, Philip Caron, Cary L. Queen, Nevenka M. Avdalovic
Publikováno v:
Molecular immunology. 30(15)
M195 is a murine monoclonal antibody that binds to the CD33 antigen and is being tested for the treatment of myeloid leukemia. Surprisingly, a complementarity determining region (CDR)-grafted, humanized M195 antibody displayed a several-fold higher b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3fa4185c346ee4d1c2e2718e37070ca
https://pubmed.ncbi.nlm.nih.gov/8232322
https://pubmed.ncbi.nlm.nih.gov/8232322