Zobrazeno 1 - 10
of 491
pro vyhledávání: '"Man Hw"'
Autor:
Peter H. Schafer, Dorota Cedzik, Helen Brady, Jilly F. Evans, G.W. Muller, Anastasia Parton, Man Hw, D.I. Stirling, Rajesh Chopra, Lori Capone
Publikováno v:
Cellular Signalling. 26:2016-2029
Apremilast, an oral small molecule inhibitor of phosphodiesterase 4 (PDE4), is in development for chronic inflammatory disorders, and has shown efficacy in psoriasis, psoriatic arthropathies, and Behçet's syndrome. In March 2014, the US Food and Dru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22011b949f5668e8f71a9ada65d0094f
https://doi.org/10.1016/j.cellsig.2014.05.014
https://doi.org/10.1016/j.cellsig.2014.05.014
Autor:
Xue Q; Department of Applied Biology and Chemical Technology, State Key Laboratory of Chemical Biology and Drug Discovery, The Hong Kong Polytechnic University Hong Kong China Twblo@polyu.edu.hk Bolong.huang@polyu.edu.hk.; The Hong Kong Polytechnic University Shenzhen Research Institute, The Hong Kong Polytechnic University Shenzhen China., Ng BKY; Department of Chemistry, Wolfson Catalysis Centre, University of Oxford Oxford OX1 3QR UK., Man HW; The Hong Kong Polytechnic University Shenzhen Research Institute, The Hong Kong Polytechnic University Shenzhen China., Wu TS; National Synchrotron Radiation Research Center 101 Hsin-Ann Road Hsinchu 30076 Taiwan., Soo YL; Department of Physics, National Tsing Hua University Hsinchu 30013 Taiwan., Li MM; Department of Applied Physics, The Hong Kong Polytechnic University Kowloon Hong Kong China., Kawaguchi S; Japan Synchrotron Radiation Research Institute (JASRI), SPring-8 1-1-1 Kouto, Sayo-cho, Sayo-gun Hyogo 679-5198 Japan., Wong KY; The Hong Kong Polytechnic University Shenzhen Research Institute, The Hong Kong Polytechnic University Shenzhen China., Tsang SCE; Department of Chemistry, Wolfson Catalysis Centre, University of Oxford Oxford OX1 3QR UK., Huang B; Department of Applied Biology and Chemical Technology, State Key Laboratory of Chemical Biology and Drug Discovery, The Hong Kong Polytechnic University Hong Kong China Twblo@polyu.edu.hk Bolong.huang@polyu.edu.hk.; The Hong Kong Polytechnic University Shenzhen Research Institute, The Hong Kong Polytechnic University Shenzhen China., Lo TWB; Department of Applied Biology and Chemical Technology, State Key Laboratory of Chemical Biology and Drug Discovery, The Hong Kong Polytechnic University Hong Kong China Twblo@polyu.edu.hk Bolong.huang@polyu.edu.hk.; The Hong Kong Polytechnic University Shenzhen Research Institute, The Hong Kong Polytechnic University Shenzhen China.
Publikováno v:
Chemical science [Chem Sci] 2021 Nov 29; Vol. 13 (1), pp. 50-58. Date of Electronic Publication: 2021 Nov 29 (Print Publication: 2021).
Autor:
Lori Capone, Loveland Ma, Cheung Yf, Lei Wu, Anita Gandhi, Peter H. Schafer, Justin B. Bartlett, Amos Gilhar, Mary Adams, George S. Baillie, D. I. Stirling, G. W. Muller, Anastasia Parton, Houslay, Man Hw
Publikováno v:
British Journal of Pharmacology. 159:842-855
Background and purpose: Apremilast is an orally administered phosphodiesterase-4 inhibitor, currently in phase 2 clinical studies of psoriasis and other chronic inflammatory diseases. The inhibitory effects of apremilast on pro-inflammatory responses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b99b2bd538e86f4b148f758f94ec804b
https://doi.org/10.1111/j.1476-5381.2009.00559.x
https://doi.org/10.1111/j.1476-5381.2009.00559.x
Autor:
Xue Q; The Hong Kong Polytechnic University Shenzhen Research Institute, Shenzhen, China. benedict.tw.lo@polyu.edu.hk., Xie Y, Wu S, Wu TS, Soo YL, Day S, Tang CC, Man HW, Yuen ST, Wong KY, Wang Y, Lo BTW, Tsang SCE
Publikováno v:
Nanoscale [Nanoscale] 2020 Nov 26; Vol. 12 (45), pp. 23206-23212.
Autor:
Shahroudi, Ali1 (AUTHOR), Habibzadeh, Sajjad1 (AUTHOR) sajjad.habibzadeh@mail.mcgill.ca
Publikováno v:
Scientific Reports. 7/22/2024, Vol. 14 Issue 1, p1-12. 12p.
Autor:
Chen R, David I. Stirling, Marriott Jb, Angus G. Dalgleish, G W Muller, Man Hw, Macdonald Cd, Keith Dredge
Publikováno v:
British Journal of Cancer
The anti-tumour effects of thalidomide have been associated with its anti-angiogenic properties. Second generation thalidomide analogues are distinct compounds with enhanced therapeutic potential. Although these compounds are beginning to enter trial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::653a3afaf21b5abbacf2c9616d2ae0ed
https://openaccess.sgul.ac.uk/id/eprint/718/1/87-6600607a.pdf
https://openaccess.sgul.ac.uk/id/eprint/718/1/87-6600607a.pdf
Autor:
Xu ZL; Department of Urology, The Third Hospital of Shijiazhuang City, Changan, Shijiazhuang, Hebei 050011, P.R. China., Zhang Y; Department of Urology, The Third Hospital of Shijiazhuang City, Changan, Shijiazhuang, Hebei 050011, P.R. China., Wang L; Orthopedic Research Center, The Third Hospital of Hebei Medical University, Qiaoxi, Shijiazhuang, Hebei 050011, P.R. China., Li F; Department of Urology, The Fourth Hospital of Hebei Medical University, Changan, Shijiazhuang, Hebei 050011, P.R. China., Man HW; Department of Clinical Laboratory, The Fourth Hospital of Hebei Medical University, Changan, Shijiazhuang, Hebei 050011, P.R. China., Li PF; Department of Clinical Laboratory, People's Hospital of Cang Zhou City, Xinhua, Cang Zhou 061000, P.R. China., Shan BE; Cancer Research Institute, The Fourth Hospital of Hebei Medical University, Changan, Shijiazhuang, Hebei 050011, P.R. China.
Publikováno v:
Oncology reports [Oncol Rep] 2018 Nov; Vol. 40 (5), pp. 2722-2733. Date of Electronic Publication: 2018 Aug 17.
Autor:
Man HW; Department of Applied Biology and Chemical Technology, The State Key Laboratory of Chirosciences, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong. lawrence.ys.lee@polyu.edu.hk., Tsang CS; Department of Applied Biology and Chemical Technology, The State Key Laboratory of Chirosciences, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong. lawrence.ys.lee@polyu.edu.hk., Li MM; Department of Chemistry, University of Oxford, Oxford, OX1 3QR, UK. edman.tsang@chem.ox.ac.uk., Mo J; Department of Chemistry, University of Oxford, Oxford, OX1 3QR, UK. edman.tsang@chem.ox.ac.uk., Huang B; Department of Applied Biology and Chemical Technology, The State Key Laboratory of Chirosciences, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong. lawrence.ys.lee@polyu.edu.hk., Lee LYS; Department of Applied Biology and Chemical Technology, The State Key Laboratory of Chirosciences, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong. lawrence.ys.lee@polyu.edu.hk., Leung YC; Department of Applied Biology and Chemical Technology, The State Key Laboratory of Chirosciences, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong. lawrence.ys.lee@polyu.edu.hk., Wong KY; Department of Applied Biology and Chemical Technology, The State Key Laboratory of Chirosciences, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong. lawrence.ys.lee@polyu.edu.hk., Tsang SCE; Department of Applied Biology and Chemical Technology, The State Key Laboratory of Chirosciences, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong. lawrence.ys.lee@polyu.edu.hk and Department of Chemistry, University of Oxford, Oxford, OX1 3QR, UK. edman.tsang@chem.ox.ac.uk.
Publikováno v:
Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2018 Aug 11; Vol. 54 (62), pp. 8630-8633. Date of Electronic Publication: 2018 Jul 18.
Autor:
Hansen JD; Celgene Corporation , 10300 Campus Point Drive, Suite 100, San Diego, California 92121, United States., Condroski K; Celgene Corporation , 10300 Campus Point Drive, Suite 100, San Diego, California 92121, United States., Correa M; Celgene Corporation , 10300 Campus Point Drive, Suite 100, San Diego, California 92121, United States., Muller G; Celgene Corporation , 10300 Campus Point Drive, Suite 100, San Diego, California 92121, United States., Man HW; Celgene Corporation , 10300 Campus Point Drive, Suite 100, San Diego, California 92121, United States., Ruchelman A; Celgene Corporation , 10300 Campus Point Drive, Suite 100, San Diego, California 92121, United States., Zhang W; Celgene Corporation , 10300 Campus Point Drive, Suite 100, San Diego, California 92121, United States., Vocanson F; Celgene Corporation , 10300 Campus Point Drive, Suite 100, San Diego, California 92121, United States., Crea T; Celgene Corporation , 10300 Campus Point Drive, Suite 100, San Diego, California 92121, United States., Liu W; Celgene Corporation , 10300 Campus Point Drive, Suite 100, San Diego, California 92121, United States., Lu G; Celgene Corporation , 10300 Campus Point Drive, Suite 100, San Diego, California 92121, United States., Baculi F; Celgene Corporation , 10300 Campus Point Drive, Suite 100, San Diego, California 92121, United States., LeBrun L; Celgene Corporation , 10300 Campus Point Drive, Suite 100, San Diego, California 92121, United States., Mahmoudi A; Celgene Corporation , 10300 Campus Point Drive, Suite 100, San Diego, California 92121, United States., Carmel G; Celgene Corporation , 10300 Campus Point Drive, Suite 100, San Diego, California 92121, United States., Hickman M; Celgene Corporation , 10300 Campus Point Drive, Suite 100, San Diego, California 92121, United States., Lu CC; Celgene Corporation , 10300 Campus Point Drive, Suite 100, San Diego, California 92121, United States.
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2018 Jan 25; Vol. 61 (2), pp. 492-503. Date of Electronic Publication: 2017 Apr 13.
Autor:
Matyskiela ME; 1Celgene Corporation , 10300 Campus Point Drive, Suite 100, San Diego, California 92121, United States., Zhang W; 1Celgene Corporation , 10300 Campus Point Drive, Suite 100, San Diego, California 92121, United States., Man HW; 1Celgene Corporation , 10300 Campus Point Drive, Suite 100, San Diego, California 92121, United States., Muller G; 1Celgene Corporation , 10300 Campus Point Drive, Suite 100, San Diego, California 92121, United States., Khambatta G; 1Celgene Corporation , 10300 Campus Point Drive, Suite 100, San Diego, California 92121, United States., Baculi F; 1Celgene Corporation , 10300 Campus Point Drive, Suite 100, San Diego, California 92121, United States., Hickman M; 1Celgene Corporation , 10300 Campus Point Drive, Suite 100, San Diego, California 92121, United States., LeBrun L; 1Celgene Corporation , 10300 Campus Point Drive, Suite 100, San Diego, California 92121, United States., Pagarigan B; 1Celgene Corporation , 10300 Campus Point Drive, Suite 100, San Diego, California 92121, United States., Carmel G; 1Celgene Corporation , 10300 Campus Point Drive, Suite 100, San Diego, California 92121, United States., Lu CC; 1Celgene Corporation , 10300 Campus Point Drive, Suite 100, San Diego, California 92121, United States., Lu G; 1Celgene Corporation , 10300 Campus Point Drive, Suite 100, San Diego, California 92121, United States., Riley M; 1Celgene Corporation , 10300 Campus Point Drive, Suite 100, San Diego, California 92121, United States., Satoh Y; 1Celgene Corporation , 10300 Campus Point Drive, Suite 100, San Diego, California 92121, United States., Schafer P; 1Celgene Corporation , 10300 Campus Point Drive, Suite 100, San Diego, California 92121, United States., Daniel TO; 1Celgene Corporation , 10300 Campus Point Drive, Suite 100, San Diego, California 92121, United States., Carmichael J; 1Celgene Corporation , 10300 Campus Point Drive, Suite 100, San Diego, California 92121, United States., Cathers BE; 1Celgene Corporation , 10300 Campus Point Drive, Suite 100, San Diego, California 92121, United States., Chamberlain PP; 1Celgene Corporation , 10300 Campus Point Drive, Suite 100, San Diego, California 92121, United States.
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2018 Jan 25; Vol. 61 (2), pp. 535-542. Date of Electronic Publication: 2017 Apr 20.