Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Man Hagiyama"'
Autor:
Makoto Yoshida, Jiayin Yuan, Takako Kihara, Neinei Kimura, Takashi Yamasaki, Mizuka Ohkouchi, Yuka Hashikura, Koji Isozaki, Man Hagiyama, Akihiko Ito, Seiichi Hirota
Publikováno v:
Experimental and Molecular Pathology, Vol 139, Iss , Pp 104922- (2024)
Gastrointestinal stromal tumor (GIST) is the most common mesenchymal tumor of the alimentary tract. The prognosis depends on the primary site, and small intestinal GISTs have a worse prognosis than gastric GISTs. Molecularly targeted drugs to inhibit
Externí odkaz:
https://doaj.org/article/ff6f35a42d4d44b584d7f21a82b1eb12
Autor:
Man Hagiyama, Azusa Yoneshige, Tomoyuki Otani, Akihiro Wada, Fuka Takeuchi, Yuji Shoya, Takao Inoue, Akihiko Ito
Publikováno v:
Molecular & Cellular Oncology, Vol 11, Iss 1 (2024)
Cell adhesion molecule 1 (CADM1), an immunoglobulin superfamily member, is expressed in endometrial glandular cells highly during the proliferative phase but lowly during the secretory phase. Previously, a CADM1–targeting antibody–drug conjugate
Externí odkaz:
https://doaj.org/article/97c6f10550dc4a26964a6818ee0e8df5
Autor:
Man Hagiyama, Takahiro Mimae, Akihiro Wada, Fuka Takeuchi, Azusa Yoneshige, Takao Inoue, Naoyuki Kotoku, Hironobu Hamada, Yoshitaka Sekido, Morihito Okada, Akihiko Ito
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Malignant pleural mesothelioma (MPM) is a highly aggressive malignant tumor, and the effective therapeutic drugs are limited. Thus, the establishment of novel therapeutic method is desired. Considerable proportion of MPMs are shown to express cell ad
Externí odkaz:
https://doaj.org/article/257be0bb6f184393914785936f0d9ed4
Autor:
Tomoyuki Otani, Kosuke Murakami, Naoki Shiraishi, Man Hagiyama, Takao Satou, Mitsuru Matsuki, Noriomi Matsumura, Akihiko Ito
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
The clinicopathological, immunohistochemical, and molecular characteristics of α-fetoprotein (AFP)-producing endometrial carcinoma (AFP+ EC) are poorly understood. From 284 cases of endometrial carcinoma in our pathology archive, we identified five
Externí odkaz:
https://doaj.org/article/b3beb8bc86a343f799a97c36f3fbb619
Autor:
Azusa Yoneshige, Man Hagiyama, Yasutoshi Takashima, Satoru Ueno, Takao Inoue, Ryuichiro Kimura, Yoshiki Koriyama, Akihiko Ito
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Elevation of intraocular pressure is a major risk factor for glaucoma development, which causes the loss of retinal ganglion cells (RGCs). Lipocalin 2 (Lcn2) is upregulated in glaucomatous retinae; however, whether Lcn2 is directly involved in glauco
Externí odkaz:
https://doaj.org/article/2046a8c0de964809b286f9ba74598736
Autor:
Man Hagiyama, Yoshihisa Nakatani, Yasutoshi Takashima, Takashi Kato, Takao Inoue, Ryuichiro Kimura, Tomoyuki Otani, Yasufumi Sato, Hideo Mori, Shuji Arima, Akihiko Ito
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
Cell adhesion molecule 1 (CADM1) is an immunoglobulin superfamily member strongly expressed on renal tubular epithelia in the urinary tract. Enzymatic cleavage of its ectodomain increases in chronic kidney disease (CKD), and is assumed to contribute
Externí odkaz:
https://doaj.org/article/bebcad7bdefc47fd839083edec530898
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 6 (2018)
A disintegrin and metalloproteinases (ADAMs) are a Zn2+-dependent transmembrane and secreted metalloprotease superfamily, so-called “molecular scissors,” and they consist of an N-terminal signal sequence, a prodomain, zinc-binding metalloprotease
Externí odkaz:
https://doaj.org/article/f495e73201b442c1935b2db8102bcb4f
Autor:
Aritoshi Ri, Man Hagiyama, Takao Inoue, Azusa Yoneshige, Ryuichiro Kimura, Yoshinori Murakami, Akihiko Ito
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 6 (2018)
Pulmonary emphysema usually arises in cigarette smokers, and often progresses after smoking cessation and even in ex-smokers. Lung-epithelial cell adhesion molecule 1 (CADM1), an immunoglobulin superfamily member, is extracellularly shed to produce a
Externí odkaz:
https://doaj.org/article/3c1249aa134441c3826d8ea522cb7154
Autor:
Man Hagiyama, Norikazu Yabuta, Daisuke Okuzaki, Takao Inoue, Yasutoshi Takashima, Ryuichiro Kimura, Aritoshi Ri, Akihiko Ito
Publikováno v:
Frontiers in Physiology, Vol 8 (2017)
Intraluminal pressure elevation can cause degenerative disorders, such as ileus and hydronephrosis, and the threshold is fairly low and constant, 20–30 cm H2O. We previously devised a novel two-chamber culture system subjecting cells cultured on a
Externí odkaz:
https://doaj.org/article/ea441fc23d6d4b368cfe60316f21c728
Autor:
Yasutoshi Takashima, Teppei Murakami, Takao Inoue, Man Hagiyama, Azusa Yoneshige, Syunji Nishimura, Masao Akagi, Akihiko Ito
Publikováno v:
Tumor Biology, Vol 39 (2017)
Epithelial carcinomas occasionally have sarcomatous components that consist primarily of spindle and cuboidal cells, which often resemble osteoblasts. Sarcomatoid carcinomas consist of similar cells. Recent studies have characterized these phenomena
Externí odkaz:
https://doaj.org/article/1f902880d8fd4fa9bf84717f7696fd48