Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Man Chun Leong"'
Autor:
Yoon-Sim Yap, Man Chun Leong, Yong Wei Chua, Kiley Wei Jen Loh, Guek Eng Lee, Elaine Hsuen Lim, Rebecca Dent, Raymond Chee Hui Ng, John Heng-Chi Lim, Garima Singh, Angela Tan, Guofeng Guan, Andrew Wu, Yi Fang Lee, Ali Asgar S Bhagat, Darren Wan-Teck Lim
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0221305 (2019)
ObjectivesWe aimed to study the prevalence of CTCs in breast cancer (BC) patients undergoing neoadjuvant or palliative therapy with a label-free microfluidic platform (ClearCell FX), and its prognostic relevance in metastatic BC (mBC).Materials and m
Externí odkaz:
https://doaj.org/article/1533eab22ed741e3a974f2c897c4cc75
Autor:
Man Chun Leong, Mei Kim Ang, Tony Kh. Lim, Chwee Teck Lim, Brendan Pang, Alvin Soon Tiong Lim, Angela Takano, Chye Ling Tan, Tse Hui Lim, Yong Wei Chua, Daniel Shao-Weng Tan, Wan-Teck Lim
Publikováno v:
Oncotarget
Anaplastic lymphoma kinase (ALK) gene rearrangement in non-small cell lung cancer (NSCLC) is routinely evaluated by fluorescent in-situ hybridization (FISH) testing on biopsy tissues. Testing can be challenging however, when suitable tissue samples a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c853b5b347e000bb2c789204b08eb8c5
http://europepmc.org/articles/PMC5029624
http://europepmc.org/articles/PMC5029624
Publikováno v:
Procedia IUTAM. 12:20-30
There has been an increased use of silicone gel for applications such as cell traction force measurements as well as lab- and organ-on-chip systems. However, silicone gel is a viscoelastic material which tends to undergo non-elastic deformation and d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab5acb6db18a67b18101c3fd9aab9b1b
https://doi.org/10.1016/j.piutam.2014.12.004
https://doi.org/10.1016/j.piutam.2014.12.004
Autor:
Rebecca Dent, Guek Eng Lee, Ali Asgar S. Bhagat, Guofeng Guan, Yong Wei Chua, Kiley Wei-Jen Loh, Elaine Hsuen Lim, Yi Fang Lee, Angela Tan, Yoon Sim Yap, Garima Singh, Man Chun Leong, Darren Wan-Teck Lim, Raymond Ng, Andrew Wu, John Heng-Chi Lim
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 9, p e0221305 (2019)
PLoS ONE, Vol 14, Iss 9, p e0221305 (2019)
ObjectivesWe aimed to study the prevalence of CTCs in breast cancer (BC) patients undergoing neoadjuvant or palliative therapy with a label-free microfluidic platform (ClearCell FX), and its prognostic relevance in metastatic BC (mBC).Materials and m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c50eab0caab725de790478a37174036
https://doi.org/10.1371/journal.pone.0221305
https://doi.org/10.1371/journal.pone.0221305
Autor:
Man Chun Leong, Han Wei Hou, Wong Cheng Lee, Chwee Teck Lim, Sri Ram Krishna Vedula, Surabhi Sonam
Publikováno v:
Cellular and Molecular Bioengineering. 4:591-602
Cell mechanics is a highly interdisciplinary research area which has made significant progress over the last decade, particularly in the study of human diseases. In diseases such as malaria and cancer, diseased cells undergo changes in both compositi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6cef659b0b7e6491711c6b95a9d53e22
https://doi.org/10.1007/s12195-011-0209-4
https://doi.org/10.1007/s12195-011-0209-4
Autor:
Chwee Teck Lim, Benoit Ladoux, Sri Ram Krishna Vedula, Hiroaki Hirata, Nir S. Gov, Alexandre Kabla, Kevin W. Doxzen, Man Chun Leong
Publikováno v:
Integrative biology : quantitative biosciences from nano to macro. 5(8)
Collective behavior refers to the emergence of complex migration patterns over scales larger than those of the individual elements constituting a system. It plays a pivotal role in biological systems in regulating various processes such as gastrulati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe41c059b7dedc788483dd4df5e27d5c
https://pubmed.ncbi.nlm.nih.gov/23784144
https://pubmed.ncbi.nlm.nih.gov/23784144
Publikováno v:
Communicative & Integrative Biology
Migrating cells constantly interact with their immediate microenvironment and neighbors. Although studies on single cell migration offer us insights into the molecular and biochemical signaling pathways, they cannot predict the influence of cell crow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a21c1640d21d1ce7f3f28803284cd759
http://europepmc.org/articles/PMC3609846
http://europepmc.org/articles/PMC3609846
Autor:
Alvin Soon Tiong Lim, Man Chun Leong, Yong Wei Chua, Rebecca Dent, Kiley Wei-Jen Loh, Raymond Ng, Andrew Wu, Chye Ling Tan, Yoon Sim Yap, Guek Eng Lee, Elaine Hsuen Lim, Wan-Teck Lim, Tse Hui Lim
Publikováno v:
Cancer Research. 76:5008-5008
Background: HER2-positive tumors are often associated with poor prognosis, chemo-resistances and some patients eventually develop refractory disease during HER2 targeted therapy. While different mechanisms of trastuzumab resistance are being identifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7363aa27b145af1308ea3a6da81c01cf
https://doi.org/10.1158/1538-7445.am2016-5008
https://doi.org/10.1158/1538-7445.am2016-5008
Autor:
Dianrong Xiu, Sin Chi Ho, Man Chun Leong, Sijia Lu, Chong Shi, Yunyun Niu, Haixing Wang, Andrew Wu, Lianyuan Tao
Publikováno v:
Journal of Clinical Oncology. 34:e23122-e23122
e23122Background: Tumor heterogeneity represents a key hallmark of cancer which complicates anti-cancer treatments. Presence of sub-clonal tumor population may be undetected through bulk tumor sequ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d03dc9d4aa0a1187d372c420878d883
https://doi.org/10.1200/jco.2016.34.15_suppl.e23122
https://doi.org/10.1200/jco.2016.34.15_suppl.e23122
Autor:
Angela Takano, Daniel Shao-Weng Tan, Tse Hui Lim, Yong Wei Chua, Chye Ling Tan, Man Chun Leong, Kiat Hon Lim, Wan-Teck Lim, Andrew Wu, Alvin St Lim
Publikováno v:
Journal of Clinical Oncology. 34:e23086-e23086
e23086Background: Fluorescence in-situ hybridization (FISH) is the reference assay for ROS1 gene rearrangement. Molecular detection of ROS1 rearrangement in lung cancer has therapeutic relevance in...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f2cd40efaa555b1caead28b47185b0e
https://doi.org/10.1200/jco.2016.34.15_suppl.e23086
https://doi.org/10.1200/jco.2016.34.15_suppl.e23086