Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Man Chin, Chung"'
Autor:
Man Chin, Chung1,2 (AUTHOR) chung.man-chin@unesp.br, Dos Santos, Jean Leandro1 (AUTHOR) chung.man-chin@unesp.br
Publikováno v:
Pharmaceuticals (14248247). Sep2023, Vol. 16 Issue 9, p1257. 4p.
Autor:
Leandro Augusto Rosseto, Maria Elisa Lopes Pires, Aylime Castanho Bolognesi Melchior, Priscila Longhin Bosquesi, Aline Renata Pavan, Sisi Marcondes, Man Chin Chung, Jean Leandro dos Santos
Publikováno v:
Molecules, Vol 20, Iss 10, Pp 18185-18200 (2015)
Thrombosis is the main outcome of many cardiovascular diseases. Current treatments to prevent thrombotic events involve the long-term use of antiplatelet drugs. However, this therapy has several limitations, thereby justifying the development of new
Externí odkaz:
https://doaj.org/article/a2db657dc6bb4d2f83d64b2875ca34d9
Autor:
Rafael Consolin Chelucci, Luiz Antônio Dutra, Maria Elisa Lopes Pires, Thais Regina Ferreira de Melo, Priscila Longhin Bosquesi, Man Chin Chung, Jean Leandro dos Santos
Publikováno v:
Molecules, Vol 19, Iss 2, Pp 2089-2099 (2014)
Nonsteroidal anti-inflammatory drugs (NSAIDs) 1–5 containing an N-acyl hydrazone subunit were prepared and their antiplatelet and antithrombotic activities assessed in vitro and in vivo. Compounds 1–5 inhibited the platelet aggregation induced by
Externí odkaz:
https://doaj.org/article/e94f9980cf8b4224ad5a42ffb4507e84
Autor:
Paulo Renato Yamasaki, Ednir Oliveira Vizioli, Jean Leandro dos Santos, Priscila Longhin Bosquesi, Pedro Malatesta, Man Chin Chung
Publikováno v:
Pharmaceuticals, Vol 5, Iss 10, Pp 1128-1146 (2012)
Amino acids are well known to be an important class of compounds for the maintenance of body homeostasis and their deficit, even for the polar neuroactive aminoacids, can be controlled by supplementation. However, for the amino acid taurine (2-aminoe
Externí odkaz:
https://doaj.org/article/986393efe011458cba833922faeda7d0
Autor:
Jean Leandro dos Santos, Man Chin Chung, Ednir Oliveira Vizioli, Priscila Longhin Bosquesi, Thais Regina Ferreira Melo
Publikováno v:
Pharmaceuticals, Vol 4, Iss 11, Pp 1450-1474 (2011)
The design of new drugs with better physiochemical properties, adequate absorption, distribution, metabolism, and excretion, effective pharmacologic potency and lacking toxicity remains is a challenge. Inflammation is the initial trigger of several d
Externí odkaz:
https://doaj.org/article/fc25e607f1b840f0b91704722282a9f8
Autor:
Man Chin Chung, Lídia Moreira Lima, Jean Leandro dos Santos, Eliana Aparecida Varanda, Priscila Longhin Bosquesi
Publikováno v:
Molecules, Vol 16, Iss 4, Pp 2982-2989 (2011)
The compounds 1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl nitrate (C1), (1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethyl nitrate (C2), 3-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)benzyl nitrate (C3), 4-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-N-hydroxy-
Externí odkaz:
https://doaj.org/article/9b8c6d16678d4cffb289edfbcb6e9cd2
Autor:
Michel Leandro Campos, Jean Leandro dos Santos, Rafael Chelucci, Man Chin Chung, Richard Chiquetto, Rosangela Gonçalves Peccinini
Publikováno v:
Molecules, Vol 15, Iss 11, Pp 8039-8047 (2010)
The new compound 1-(2-chloro-6-fluorophenyl)-5-methylindolin-2-one (1), designed using the prodrug approach, was easily obtained in 85% yield and characterized by nuclear magnetic resonance, elemental analysis, mass spectrometry and infrared spectros
Externí odkaz:
https://doaj.org/article/74c935c09da84240bf944f852e78e521
Autor:
Man Chin Chung, Jean Leandro dos Santos, Ednir Vizioli Oliveira, Lorena Blau, Renato Farina Menegon, Rosângela Gonçalves Peccinini
Publikováno v:
Molecules, Vol 14, Iss 9, Pp 3187-3197 (2009)
The compound 1-(2,6-dichlorophenyl)indolin-2-one (1), planned as a pro-drug of diclofenac (2), was easily synthesized in 94% yield by an intramolecular reaction in the presence of coupling agent (i.e., EDC). Compound 1 showed anti-inflammatory and an
Externí odkaz:
https://doaj.org/article/8f4188048bea48b2b5bc5cf916c10b99
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Man-Chin Chung, Vladimir Constantino Gomes Heleno, Leila Aley Tavares, Elisangela Fabiana Boffo, Antonio Gilberto Ferreira, Elizabeth Igne Ferreira, Renato Farina Menegon, Lorena Blau
Publikováno v:
Molecules, Vol 13, Iss 4, Pp 841-854 (2008)
We report the synthesis and total NMR characterization of 5-thia-1-azabicyclo-[4.2.0]oct-2-ene-2-carboxylic acid-3-[[[(4’’-nitrophenoxy)carbonyl]oxy]-methyl]-8-oxo-7-[(2-thienyloxoacetyl)amino]-diphenylmethyl ester-5-dioxide
Externí odkaz:
https://doaj.org/article/d028c6552f294c4a9b4981946b5a17ba