Zobrazeno 1 - 10
of 318
pro vyhledávání: '"Man‐Sau Wong"'
Publikováno v:
Exploration, Vol 4, Iss 4, Pp n/a-n/a (2024)
Abstract Cornea is the major barrier to drug delivery to the eye, which results in low bioavailability and poor efficacy of topical eye treatment. In this work, we first select cornea‐binding aptamers using tissue‐SELEX on pig cornea. The top two
Externí odkaz:
https://doaj.org/article/a4ed6ac26890489185779eb8664bc57a
Publikováno v:
Biomedical Journal, Vol 47, Iss 4, Pp 100685- (2024)
Among the various targeting ligands for drug delivery, aptamers have attracted much interest in recent years because of their smaller size compared to antibodies, ease of modification, and better batch-to-batch consistency. In addition, aptamers can
Externí odkaz:
https://doaj.org/article/eddc534adcdb4f008f185321d8036afd
Autor:
Wen-Xuan Yu, Hok-Him Tang, Jun-Jie Ye, Hui-Hui Xiao, Chung-Yan Lam, Tim-Fat Shum, Zhi-Kang Sun, Yuan-Zhen Li, Xin-Yu Zang, Wen-Chao Du, Jian-Ping Zhang, Tsz-Hung Kong, Li-Ping Zhou, Jia-Chi Chiou, Chun-Fai Kung, Kam-Wah Mok, Jing Hu, Man-Sau Wong
Publikováno v:
Molecules, Vol 28, Iss 15, p 5742 (2023)
Secoisolariciresinol (SECO) is one of the major lignans occurring in various grains, seeds, fruits, and vegetables. The gut microbiota plays an important role in the biotransformation of dietary lignans into enterolignans, which might exhibit more po
Externí odkaz:
https://doaj.org/article/8dacd9cdd0004fb998b61c380a59cedb
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
IntroductionIn postmenopausal women, vitamin D deficiency (as defined by the circulating level of 25(OH)D being below 20 ng/ml (50 nmol/L)) is a regular occurrence. The effect of vitamin D supplementation on the muscle function of postmenopausal wome
Externí odkaz:
https://doaj.org/article/9c554276794949978c38cf4896e6e31e
Autor:
Liping Zhou, Ka-Ying Wong, Christina Chui-Wa Poon, Wenxuan Yu, Huihui Xiao, Chi-On Chan, Daniel Kam-Wah Mok, Man-Sau Wong
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Our previous study demonstrated that the bone protective actions of herbal medicine Rhizoma Drynariae (Gusuibu, RD) were mainly mediated by flavonoid phytoestrogens via estrogen receptors, raising concerns about the safety of using RD as it may induc
Externí odkaz:
https://doaj.org/article/4daefdc4322a4ed9ad2fd8e538e7ca2e
Autor:
Yu-Xin Zhu, Zi-Ling Tang, Lu Lu, Zuo-Cheng Qiu, Dabo Pan, Yang Yu, Hui-Hui Xiao, Man-Sau Wong
Publikováno v:
Acupuncture & Herbal Medicine; Mar2024, Vol. 4 Issue 1, p102-112, 11p
Autor:
Zuo-Cheng Qiu, Feng-Xiang Zhang, Xue-Ling Hu, Yang-Yang Zhang, Zi-Ling Tang, Jie Zhang, Li Yang, Man-Sau Wong, Jia-Xu Chen, Hui-Hui Xiao
Publikováno v:
Molecules, Vol 27, Iss 22, p 7811 (2022)
Postmenopausal osteoporosis is a significant threat to human health globally. Genistein, a soy-derived isoflavone, is regarded as a promising anti-osteoporosis drug with the effects of promoting osteoblastogenesis and suppressing osteoclastogenesis.
Externí odkaz:
https://doaj.org/article/592963016e4e4d949ee3204f698e3c0c
Autor:
Quan-Gui Gao, Li-Ping Zhou, Vien Hoi-Yi Lee, Hoi-Yi Chan, Cornelia Wing-Yin Man, Man-Sau Wong
Publikováno v:
Journal of Ginseng Research, Vol 43, Iss 4, Pp 527-538 (2019)
Background: Ginsenoside Rg1 was shown to exert ligand-independent activation of estrogen receptor (ER) via mitogen-activated protein kinase–mediated pathway. Our study aimed to delineate the mechanisms by which Rg1 activates the rapid ER signaling
Externí odkaz:
https://doaj.org/article/11a71ab9d16645aa826959ad145575ac
Autor:
Liping Zhou, Ka-Ying Wong, Wenxuan Yu, Christina Chui-Wa Poon, Huihui Xiao, Chi-On Chan, Daniel Kam-Wah Mok, Yan Zhang, Man-Sau Wong
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2021)
Herbaepimedii (HEP), a kidney-tonifying herb, has been commonly used alone or in formula for strengthening kidney function and treating bone disorders. Its bone protective activity has been demonstrated to be via estrogen receptor (ERs). HEP activate
Externí odkaz:
https://doaj.org/article/a60a0c4c23b948eea48999a0134da44d
Publikováno v:
Journal of Materials Chemistry B. 11:4684-4694
Liposomes loaded with a dry eye disease drug, cyclosporine A (CsA) and coated with an anti-mucin aptamer are able to enhance drug delivery and the efficacy of CsA in treating dry eye diseases.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56e4b32b5655cca2471d359b6b58b282
https://doi.org/10.1039/d3tb00598d
https://doi.org/10.1039/d3tb00598d