Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Man‐Hong Leung"'
Publikováno v:
Life, Vol 14, Iss 8, p 1044 (2024)
In the original publication (doi: 10 [...]
Externí odkaz:
https://doaj.org/article/e5f760e46110471dacd5dcc9430177f7
Autor:
Ka‐Chun Mok, Ho Tsoi, Ellen PS Man, Man‐Hong Leung, Ka Man Chau, Lai‐San Wong, Wing‐Lok Chan, Sum‐Yin Chan, Mai‐Yee Luk, Jessie Y.W. Chan, Jackie K.M. Leung, Yolanda H.Y. Chan, Sellma Batalha, Virginia Lau, David C.W. Siu, Terence K.W. Lee, Chun Gong, Ui‐Soon Khoo
Publikováno v:
Clinical and Translational Medicine, Vol 11, Iss 11, Pp n/a-n/a (2021)
Abstract Hyperpolarization‐activated cyclic nucleotide‐gated (HCN) channels are members of the voltage‐gated cation channel family known to be expressed in the heart and central nervous system. Ivabradine, a small molecule HCN channel‐blocker
Externí odkaz:
https://doaj.org/article/89dc802a66c04d34bba35fe0b981b854
Autor:
Ho Tsoi, Ellen PS Man, Man‐Hong Leung, Ka‐Chun Mok, Ka‐Man Chau, Lai‐San Wong, Wing‐Lok Chan, Sum‐Yin Chan, Mai‐Yee Luk, Cheuk‐Nam Cheng, Ui‐Soon Khoo
Publikováno v:
Clinical and Translational Medicine, Vol 11, Iss 10, Pp n/a-n/a (2021)
Externí odkaz:
https://doaj.org/article/716f99050a144c3382dee490266c2561
Publikováno v:
Biomolecules, Vol 12, Iss 1, p 72 (2022)
Biomarkers can be used for diagnosis, prognosis, and prediction in targeted therapy. The estrogen receptor α (ERα) and human epidermal growth factor receptor 2 (HER2) are standard biomarkers used in breast cancer for guiding disease treatment. The
Externí odkaz:
https://doaj.org/article/4491e14a9c0c4dba88ebeb266f5190ac
Publikováno v:
Life, Vol 12, Iss 1, p 93 (2022)
NCOR2 is a co-repressor for estrogen receptor (ER) and androgen receptor (AR). Our group previously identified a novel splice variant of NCOR2, BQ323636.1 (BQ), that mediates tamoxifen resistance via interference of NCOR2 repression on ER. Luciferase
Externí odkaz:
https://doaj.org/article/60b6e5ba3dc749a3a9b45f9728cfa461
Autor:
Ho Tsoi, Nicholas Nok-Ching Fung, Ellen P. S. Man, Man-Hong Leung, Chan-Ping You, Wing-Lok Chan, Sum-Yin Chan, Ui-Soon Khoo
Publikováno v:
Cancers; Volume 15; Issue 8; Pages: 2271
About 70% of breast cancer patients are oestrogen receptor-positive (ER +ve). Adjuvant endocrine therapy using tamoxifen (TAM) is an effective approach for preventing local recurrence and metastasis. However, around half of the patients will eventual
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d9e11614c2589ccc29aee2183bb477e
Autor:
Ho Tsoi, Wai-Chung Tsang, Ellen P. S. Man, Man-Hong Leung, Chan-Ping You, Sum-Yin Chan, Wing-Lok Chan, Ui-Soon Khoo
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 20; Pages: 12290
Breast cancer is a heterogeneous disease. Tamoxifen is frequently used to treat ER-positive breast cancer. Our team has identified a novel splice variant of NCOR2, BQ323636.1 (BQ), that mediates tamoxifen resistance. However, the upstream factors tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::259bc96e82e1b81eb8a181fa97d1e728
Publikováno v:
Cancers. 14(5)
Breast cancer is a heterogeneous disease. Around 70% of breast cancers are estrogen receptor-positive (ER+ve), with tamoxifen being most commonly used as an adjuvant treatment to prevent recurrence and metastasis. However, half of the patients will e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27476c675e3ef83ed783a83b3cb661c3
https://pubmed.ncbi.nlm.nih.gov/35267559
https://pubmed.ncbi.nlm.nih.gov/35267559
Autor:
Jackie K M Leung, Chun Gong, Virginia Lau, E P S Man, Sellma Batalha, Lai-San Wong, Ka Man Chau, Jessie Y.W. Chan, Mai-Yee Luk, David C.W. Siu, Sum-Yin Chan, Ka-Chun Mok, Terence K.W. Lee, Wing-Lok Chan, Man-Hong Leung, Ho Tsoi, Ui-Soon Khoo, Yolanda H. Y. Chan
Publikováno v:
Clinical and Translational Medicine, Vol 11, Iss 11, Pp n/a-n/a (2021)
Clinical and Translational Medicine
Clinical and Translational Medicine
Hyperpolarization‐activated cyclic nucleotide‐gated (HCN) channels are members of the voltage‐gated cation channel family known to be expressed in the heart and central nervous system. Ivabradine, a small molecule HCN channel‐blocker, is FDA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c44da4d7d844f456c4119f714059b8ed
https://doi.org/10.1002/ctm2.578
https://doi.org/10.1002/ctm2.578
Autor:
Ka‐Man Chau, Ellen Ps Man, Sum-Yin Chan, Man‐Hong Leung, Ui-Soon Khoo, Wing-Lok Chan, Lai-San Wong, Ho Tsoi, Ka‐Chun Mok, Mai-Yee Luk, Cheuk‐Nam Cheng
Publikováno v:
Clinical and Translational Medicine
Clinical and Translational Medicine, Vol 11, Iss 10, Pp n/a-n/a (2021)
Clinical and Translational Medicine, Vol 11, Iss 10, Pp n/a-n/a (2021)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b8cf79f24e2a4bd15054fada268fa6e
https://pubmed.ncbi.nlm.nih.gov/34709749
https://pubmed.ncbi.nlm.nih.gov/34709749