Zobrazeno 1 - 10
of 940
pro vyhledávání: '"Mamourian, A."'
Autor:
Junhao Wen, Zhijian Yang, Ilya M. Nasrallah, Yuhan Cui, Guray Erus, Dhivya Srinivasan, Ahmed Abdulkadir, Elizabeth Mamourian, Gyujoon Hwang, Ashish Singh, Mark Bergman, Jingxuan Bao, Erdem Varol, Zhen Zhou, Aleix Boquet-Pujadas, Jiong Chen, Arthur W. Toga, Andrew J. Saykin, Timothy J. Hohman, Paul M. Thompson, Sylvia Villeneuve, Randy Gollub, Aristeidis Sotiras, Katharina Wittfeld, Hans J. Grabe, Duygu Tosun, Murat Bilgel, Yang An, Daniel S. Marcus, Pamela LaMontagne, Tammie L. Benzinger, Susan R. Heckbert, Thomas R. Austin, Lenore J. Launer, Mark Espeland, Colin L. Masters, Paul Maruff, Jurgen Fripp, Sterling C. Johnson, John C. Morris, Marilyn S. Albert, R. Nick Bryan, Susan M. Resnick, Luigi Ferrucci, Yong Fan, Mohamad Habes, David Wolk, Li Shen, Haochang Shou, Christos Davatzikos
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Alzheimer’s disease (AD) is associated with heterogeneous atrophy patterns. We employed a semi-supervised representation learning technique known as Surreal-GAN, through which we identified two latent dimensional representations of brain a
Externí odkaz:
https://doaj.org/article/56d631e8319148739bce0f8e8b35d005
Autor:
Yang, Zhijian, Wen, Junhao, Abdulkadir, Ahmed, Cui, Yuhan, Erus, Guray, Mamourian, Elizabeth, Melhem, Randa, Srinivasan, Dhivya, Govindarajan, Sindhuja T., Chen, Jiong, Habes, Mohamad, Masters, Colin L., Maruff, Paul, Fripp, Jurgen, Ferrucci, Luigi, Albert, Marilyn S., Johnson, Sterling C., Morris, John C., LaMontagne, Pamela, Marcus, Daniel S., Benzinger, Tammie L. S., Wolk, David A., Shen, Li, Bao, Jingxuan, Resnick, Susan M., Shou, Haochang, Nasrallah, Ilya M., Davatzikos, Christos
Disease heterogeneity has been a critical challenge for precision diagnosis and treatment, especially in neurologic and neuropsychiatric diseases. Many diseases can display multiple distinct brain phenotypes across individuals, potentially reflecting
Externí odkaz:
http://arxiv.org/abs/2301.10772
Autor:
Mathilde Antoniades, Dhivya Srinivasan, Junhao Wen, Guray Erus, Ahmed Abdulkadir, Elizabeth Mamourian, Randa Melhem, Gyujoon Hwang, Yuhan Cui, Sindhuja Tirumalai Govindarajan, Andrew A. Chen, Zhen Zhou, Zhijian Yang, Jiong Chen, Raymond Pomponio, Susan Sotardi, Yang An, Murat Bilgel, Pamela LaMontagne, Ashish Singh, Tammie Benzinger, Lori Beason-Held, Daniel S. Marcus, Kristine Yaffe, Lenore Launer, John C. Morris, Duygu Tosun, Luigi Ferrucci, R. Nick Bryan, Susan M. Resnick, Mohamad Habes, David Wolk, Yong Fan, Ilya M. Nasrallah, Haochang Shou, Christos Davatzikos
Publikováno v:
EBioMedicine, Vol 109, Iss , Pp 105399- (2024)
Summary: Background: Brain ageing is highly heterogeneous, as it is driven by a variety of normal and neuropathological processes. These processes may differentially affect structural and functional brain ageing across individuals, with more pronounc
Externí odkaz:
https://doaj.org/article/782b783c1fc740c68d12c609c91452e4
Autor:
Junhao Wen, Bingxin Zhao, Zhijian Yang, Guray Erus, Ioanna Skampardoni, Elizabeth Mamourian, Yuhan Cui, Gyujoon Hwang, Jingxuan Bao, Aleix Boquet-Pujadas, Zhen Zhou, Yogasudha Veturi, Marylyn D. Ritchie, Haochang Shou, Paul M. Thompson, Li Shen, Arthur W. Toga, Christos Davatzikos
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract The complex biological mechanisms underlying human brain aging remain incompletely understood. This study investigated the genetic architecture of three brain age gaps (BAG) derived from gray matter volume (GM-BAG), white matter microstructu
Externí odkaz:
https://doaj.org/article/0b986bda725642da9bd3943d43862752
Autor:
Antoniades, Mathilde, Srinivasan, Dhivya, Wen, Junhao, Erus, Guray, Abdulkadir, Ahmed, Mamourian, Elizabeth, Melhem, Randa, Hwang, Gyujoon, Cui, Yuhan, Govindarajan, Sindhuja Tirumalai, Chen, Andrew A., Zhou, Zhen, Yang, Zhijian, Chen, Jiong, Pomponio, Raymond, Sotardi, Susan, An, Yang, Bilgel, Murat, LaMontagne, Pamela, Singh, Ashish, Benzinger, Tammie, Beason-Held, Lori, Marcus, Daniel S., Yaffe, Kristine, Launer, Lenore, Morris, John C., Tosun, Duygu, Ferrucci, Luigi, Bryan, R. Nick, Resnick, Susan M., Habes, Mohamad, Wolk, David, Fan, Yong, Nasrallah, Ilya M., Shou, Haochang, Davatzikos, Christos
Publikováno v:
In eBioMedicine November 2024 109
Autor:
Jun Guo, Anahita Fathi Kazerooni, Erik Toorens, Hamed Akbari, Fanyang Yu, Chiharu Sako, Elizabeth Mamourian, Russell T. Shinohara, Constantinos Koumenis, Stephen J. Bagley, Jennifer J. D. Morrissette, Zev A. Binder, Steven Brem, Suyash Mohan, Robert A. Lustig, Donald M. O’Rourke, Tapan Ganguly, Spyridon Bakas, MacLean P. Nasrallah, Christos Davatzikos
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Glioblastoma is a highly heterogeneous disease, with variations observed at both phenotypical and molecular levels. Personalized therapies would be facilitated by non-invasive in vivo approaches for characterizing this heterogeneity. In this
Externí odkaz:
https://doaj.org/article/f5997dcf88784ed0a9eb262aa340f854
Autor:
Zhijian Yang, Junhao Wen, Ahmed Abdulkadir, Yuhan Cui, Guray Erus, Elizabeth Mamourian, Randa Melhem, Dhivya Srinivasan, Sindhuja T. Govindarajan, Jiong Chen, Mohamad Habes, Colin L. Masters, Paul Maruff, Jurgen Fripp, Luigi Ferrucci, Marilyn S. Albert, Sterling C. Johnson, John C. Morris, Pamela LaMontagne, Daniel S. Marcus, Tammie L. S. Benzinger, David A. Wolk, Li Shen, Jingxuan Bao, Susan M. Resnick, Haochang Shou, Ilya M. Nasrallah, Christos Davatzikos
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Disease heterogeneity has been a critical challenge for precision diagnosis and treatment, especially in neurologic and neuropsychiatric diseases. Many diseases can display multiple distinct brain phenotypes across individuals, potentially r
Externí odkaz:
https://doaj.org/article/e4408877453444c49479a4dba3887d8a
Autor:
Wen, Junhao, Fu, Cynthia H. Y., Tosun, Duygu, Veturi, Yogasudha, Yang, Zhijian, Abdulkadir, Ahmed, Mamourian, Elizabeth, Srinivasan, Dhivya, Bao, Jingxuan, Erus, Guray, Shou, Haochang, Habes, Mohamad, Doshi, Jimit, Varol, Erdem, Mackin, Scott R, Sotiras, Aristeidis, Fan, Yong, Saykin, Andrew J., Sheline, Yvette I., Shen, Li, Ritchie, Marylyn D., Wolk, David A., Albert, Marilyn, Resnick, Susan M., Davatzikos, Christos
Late-life depression (LLD) is characterized by considerable heterogeneity in clinical manifestation. Unraveling such heterogeneity would aid in elucidating etiological mechanisms and pave the road to precision and individualized medicine. We sought t
Externí odkaz:
http://arxiv.org/abs/2110.11347
Autor:
Hwang, Gyujoon, Abdulkadir, Ahmed, Erus, Guray, Habes, Mohamad, Pomponio, Raymond, Shou, Haochang, Doshi, Jimit, Mamourian, Elizabeth, Rashid, Tanweer, Bilgel, Murat, Fan, Yong, Sotiras, Aristeidis, Srinivasan, Dhivya, Morris, John C., Marcus, Daniel, Albert, Marilyn S., Bryan, Nick R., Resnick, Susan M., Nasrallah, Ilya M., Davatzikos, Christos, Wolk, David A.
Neuroimaging biomarkers that distinguish between typical brain aging and Alzheimer's disease (AD) are valuable for determining how much each contributes to cognitive decline. Machine learning models can derive multi-variate brain change patterns rela
Externí odkaz:
http://arxiv.org/abs/2109.03723
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