Pancreatic stromal Gremlin 1 expression during pancreatic tumorigenesis

Autor: Joy M. Davis, Binglu Cheng, Madeline M. Drake, Qiang Yu, Baibing Yang, Jing Li, Chunhui Liu, Mamoun Younes, Xiurong Zhao, Jennifer M. Bailey, Qiang Shen, Tien C. Ko, Yanna Cao

Publikováno v: Genes and Diseases, Vol 9, Iss 1, Pp 108-115 (2022)

Chronic pancreatitis (CP) is a major risk factor of pancreatic ductal adenocarcinoma (PDAC). How CP promotes pancreatic oncogenesis remains unclear. A characteristic feature of PDAC is its prominent desmoplasia in the tumor microenvironment, composed

Externí odkaz: https://doaj.org/article/94e40cedec3044679e7cad005c71378b

Telomere dysfunction activates YAP1 to drive tissue inflammation

Autor: Deepavali Chakravarti, Baoli Hu, Xizeng Mao, Asif Rashid, Jiexi Li, Jun Li, Wen-ting Liao, Elizabeth M. Whitley, Prasenjit Dey, Pingping Hou, Kyle A. LaBella, Andrew Chang, Guocan Wang, Denise J. Spring, Pingna Deng, Di Zhao, Xin Liang, Zhengdao Lan, Yiyun Lin, Sharmistha Sarkar, Christopher Terranova, Yonathan Lissanu Deribe, Sarah E. Blutt, Pablo Okhuysen, Jianhua Zhang, Eduardo Vilar, Ole Haagen Nielsen, Andrew Dupont, Mamoun Younes, Kalyani R. Patel, Noah F. Shroyer, Kunal Rai, Mary K. Estes, Y. Alan Wang, Alison A. Bertuch, Ronald A. DePinho

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)

How telomere dysfunction is directly linked to inflammation in humans is currently unclear. Here the authors reveal that telomere dysfunction drives activation of the YAP1 transcription factor, up-regulating the pro inflammatory factor, pro-IL-18 thu

Externí odkaz: https://doaj.org/article/b5a35bee98a746039f8bae5793248657

Supplemental figure legends from p120 Catenin Suppresses Basal Epithelial Cell Extrusion in Invasive Pancreatic Neoplasia

Autor: Jennifer M. Bailey, Steven D. Leach, Christine A. Iacobuzio-Donahue, Mamoun Younes, Michael Goggins, Albert B. Reynolds, Anirban Maitra, Matthias Hebrok, Yanna Cao, Samuel G. Savidge, Nilotpal Roy, Hao Zhang, Kelly J. Lafaro, Ishrat Ahmed, Janivette Alsina, Kishore Polireddy, Yue J. Wang, Audrey M. Hendley

This document provides detailed captions for figures S1-S8.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::704970afcd2c29ed581afdd8e491a31c
https://doi.org/10.1158/0008-5472.22409141.v1

Supplemental table 1 from p120 Catenin Suppresses Basal Epithelial Cell Extrusion in Invasive Pancreatic Neoplasia

Autor: Jennifer M. Bailey, Steven D. Leach, Christine A. Iacobuzio-Donahue, Mamoun Younes, Michael Goggins, Albert B. Reynolds, Anirban Maitra, Matthias Hebrok, Yanna Cao, Samuel G. Savidge, Nilotpal Roy, Hao Zhang, Kelly J. Lafaro, Ishrat Ahmed, Janivette Alsina, Kishore Polireddy, Yue J. Wang, Audrey M. Hendley

This table provides a description of antibodies used in this study.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cf183fa96a77928cdf61105bd61a633
https://doi.org/10.1158/0008-5472.22409138.v1

Ensuring remote diagnostics for pathologists: an open letter to the US Congress

Autor: Jochen K. Lennerz, Liron Pantanowitz, Mitual B. Amin, Isam-Eldin Eltoum, Meera R. Hameed, Alexana N. Kalof, Elham Khanafshar, Lakshmi P. Kunju, Audrey J. Lazenby, Kathleen T. Montone, Christopher N. Otis, Michelle D. Reid, Paul N. Staats, Christa L. Whitney-Miller, Catherine S. Abendroth, Manju Aron, George G. Birdsong, Ira J. Bleiweiss, Mary P. Bronner, Jennifer Chapman, Nicole A. Cipriani, Gustavo de la Roza, Michael J. Esposito, Oluwole Fadare, Karen Ferrer, Christopher D. Fletcher, David P. Frishberg, Fernando U. Garcia, Laurette Geldenhuys, Ryan M. Gill, Dorina Gui, Shams Halat, Omar Hameed, Jason L. Hornick, Aaron R. Huber, Dhanpat Jain, Nirag Jhala, Merce Jorda, Julie M. Jorns, Jeffrey Kaplan, Mahmoud A. Khalifa, Ashraf Khan, Grace E. Kim, Eun Y. Lee, Virginia A. LiVolsi, Teri Longacre, Cristina Magi-Galluzzi, Shannon J. McCall, Laron McPhaul, Vikas Mehta, Mihai Merzianu, Stacey B. Miller, Kyle H. Molberg, Andre L. Moreira, Bita V. Naini, Vania Nosé, Kathleen O’Toole, Maria Picken, Victor G. Prieto, James M. Pullman, Charles M. Quick, Jordan P. Reynolds, Andrew E. Rosenberg, Stuart J. Schnitt, Mary R. Schwartz, Marin Sekosan, Michael T. Smith, Aliyah Sohani, Anne Stowman, Vijay K. Vanguri, Beverly Wang, John C. Watts, Shi Wei, Kathleen Whitney, Mamoun Younes, Sui Zee, Erika R. Bracamonte

Publikováno v: Nature Medicine. 28:2453-2455

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2eda1dce3f942f91155887029de8834
https://doi.org/10.1038/s41591-022-02040-6