Zobrazeno 1 - 10
of 138
pro vyhledávání: '"Mamoru Ouchida"'
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S191- (2023)
Externí odkaz:
https://doaj.org/article/0da36e0bf1424b7581790fe10e722bc9
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Considering the role of epidermal keratinocytes, they occupy more than 90% of the epidermis, form a physical barrier, and also function as innate immune barrier. For example, epidermal keratinocytes are capable of recognizing various cytokines and pa
Externí odkaz:
https://doaj.org/article/97f13161229e420b89942e9649747891
Publikováno v:
Neurobiology of Disease, Vol 175, Iss , Pp 105921- (2022)
Thioredoxin, encoded by Txn1, acts as a critical antioxidant in the defense against oxidative stress by regulating the dithiol/disulfide balance of interacting proteins. The role of thioredoxin in the central nervous system (CNS) is largely unknown.
Externí odkaz:
https://doaj.org/article/023744fe584f4bc3b2f95c0708192409
Multifaceted Analysis of IL-23A- and/or EBI3-Including Cytokines Produced by Psoriatic Keratinocytes
Autor:
Kota Tachibana, Nina Tang, Hitoshi Urakami, Ai Kajita, Mina Kobashi, Hayato Nomura, Minori Sasakura, Satoru Sugihara, Fan Jiang, Nahoko Tomonobu, Masakiyo Sakaguchi, Mamoru Ouchida, Shin Morizane
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 23, p 12659 (2021)
Interleukin (IL) 23 (p19/p40) plays a critical role in the pathogenesis of psoriasis and is upregulated in psoriasis skin lesions. In clinical practice, anti-IL-23Ap19 antibodies are highly effective against psoriasis. IL-39 (p19/ Epstein-Barr virus-
Externí odkaz:
https://doaj.org/article/4f356b82f4e541589850fc23de2157ae
Publikováno v:
Journal of Dentistry Indonesia, Vol 8, Iss 2, Pp 60-64 (2015)
Tumor specific mutation of the candidate tumor suppressor gene INGI ws demonstrated using PCR-SSCP and DNA sequencing analysis. The mutant sample showed an amino acid change from aspangine (AAC) to serine (AGC) at codon 214 in the INGI gene from the
Externí odkaz:
https://doaj.org/article/94facc038c694545a852963881d5edb2
Autor:
Iori Ohmori, Mamoru Ouchida, Katsuhiro Kobayashi, Yoshimi Jitsumori, Akiko Mori, Hiroyuki Michiue, Teiichi Nishiki, Yoko Ohtsuka, Hideki Matsui
Publikováno v:
Neurobiology of Disease, Vol 50, Iss , Pp 209-217 (2013)
Dravet syndrome is an intractable epileptic syndrome beginning in the first year of life. De novo mutations of SCN1A, which encode the Nav1.1 neuronal voltage-gated sodium channel, are considered the major cause of Dravet syndrome. In this study, we
Externí odkaz:
https://doaj.org/article/d6481db8d63c48708e357eb4461ec7fa
Publikováno v:
Journal of Dentistry Indonesia, Vol 8, Iss 1 (2015)
DNA cloning is one of the most important techniques In the field of molecular biology, with a critical role in analyzing the structure and function of genes and their adjacent regulatory regions. DNA cloning is helpful in learning fundamental molecul
Externí odkaz:
https://doaj.org/article/637163d9a16245c896719b59c6f105a0
Publikováno v:
Cancers, Vol 3, Iss 1, Pp 568-581 (2011)
Although cancers have been thought to be predominantly driven by acquired genetic changes, it is becoming clear that microenvironment-mediated epigenetic alterations play important roles. Aberrant promoter hypermethylation is a prevalent phenomenon i
Externí odkaz:
https://doaj.org/article/8d103a9dde644076872481470b787ac6
Autor:
Iori Ohmori, Mamoru Ouchida, Takafumi Miki, Nobuyoshi Mimaki, Shigeki Kiyonaka, Teiichi Nishiki, Kazuhito Tomizawa, Yasuo Mori, Hideki Matsui
Publikováno v:
Neurobiology of Disease, Vol 32, Iss 3, Pp 349-354 (2008)
Mutations of SCN1A, encoding the voltage-gated sodium channel α1 subunit, represent the most frequent genetic cause of severe myoclonic epilepsy in infancy (SMEI). The purpose of this study was to determine if mutations in other seizure susceptibili
Externí odkaz:
https://doaj.org/article/fdd99056bdb644738dd65a5b87db10f8
Autor:
Yoshihisa Kitamura, Kazuhiko Shibata, Kozue Akiyama, Shizue Kimoto, Yoshika Fujitani, Kouhei Kitagawa, Hirotaka Kanzaki, Mamoru Ouchida, Kenji Shimizu, Hiromu Kawasaki, Toshiaki Sendo, Yutaka Gomita
Publikováno v:
Journal of Pharmacological Sciences, Vol 106, Iss 1, Pp 100-106 (2008)
We examined the influence of imipramine, a traditional tricyclic antidepressant, on the binding to serotonin (5-HT)2receptors and levels of 5-HT2A–receptor mRNA in the frontal cortex of rats treated with adrenocorticotropic hormone (ACTH). Chronic
Externí odkaz:
https://doaj.org/article/8396a498c99643dc8648f02bf041ad10