Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Mamoru Miyazawa"'
Autor:
Mamoru Miyazawa1 s3f102300089@iniad.org
Publikováno v:
European Conference on Knowledge Management. 2024, Vol. 25 Issue 1, p1043-1050. 8p.
Autor:
Masao Tokuda, Mamoru Miyazawa, Takeshi Ohkuma, Hisanori Senboku, Kazuhiko Orito, Yu Onozaki, Takatoshi Nakamura, Akiyoshi Horibata, Nobuhito Kurono, Takashi Tokuhashi
Publikováno v:
Journal of Heterocyclic Chemistry. 50:E48-E54
A variety of alkoxy-substituted benzolactams with a berbine or yohimbane skeleton were prepared from 1-benzyl-1,2,3,4-tetrahydroisoquinolines or 1-benzyl-1,2,3,4-tetrahydro-β-carbolines by a phosphine-free Pd(II)-catalyzed direct aromatic carbonylat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66621aeed1527db4607ff1f8073d4c7d
https://doi.org/10.1002/jhet.1044
https://doi.org/10.1002/jhet.1044
Autor:
Hirofumi Kuroda, Huiming Zhang, Yuki Komatsu, Naoki Asakawa, Yongbo Hu, Akio Kayano, Takashi Hasebe, Takashi Kajima, Xiang Niu, Yorihisa Hoshino, Charles E. Chase, Francis G. Fang, Tomohiro Watanabe, Hiroyuki Ishizuka, Thomas Noland, Matthew J. Schnaderbeck, Thomas E. Horstmann, Naoki Asai, Mamoru Miyazawa, Katsuya Tagami, Brian Austad, Manabu Kubota, John D. Orr, Trevor Lee Calkins, Hiroyuki Chiba, Bryan M. Lewis
Publikováno v:
Synlett. 24:333-337
The evolution of the synthesis of Halaven® (E7389, INN eribulin mesylate) from a medicinal chemistry process to the execution of the final process on pilot scale is described. The completion of the synthesis of Halaven® from C1–C13 ester and C14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cd614ef0861f50badf9f4d38d2284d9
https://doi.org/10.1055/s-0032-1318026
https://doi.org/10.1055/s-0032-1318026
Autor:
Takatoshi Nakamura, Hideo Nagasaki, Mamoru Miyazawa, Masao Tokuda, Motoki Yuguchi, Tetsuro Yamazaki, Kazuhiko Orito, Satoshi Yamashita, Akiyoshi Horibata, Harumi Ushito
Publikováno v:
The Journal of Organic Chemistry. 71:5951-5958
A phosphine-free catalytic system [Pd(OAc)2-Cu(OAc)2-air] induced a substrate-specific carbonylation of amines in boiling toluene under CO gas (1 atm). Symmetrical N,N'-dialkylureas were obtained by the carbonylation of primary amines. N,N,N'-Trialky
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0545dd92d9fd152dd297c031efcf6184
https://doi.org/10.1021/jo060612n
https://doi.org/10.1021/jo060612n
Publikováno v:
Organic Process Research & Development. 7:191-195
In our investigation to efficiently remove residual palladium from a drug candidate prepared via the Suzuki−Miyaura coupling reaction, it was found that polymer-bound ethylenediamines can absorb both Pd(0) and Pd(II). This property was applied to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd9f8fb74fd071065202d14a971b0689
https://doi.org/10.1021/op0255682
https://doi.org/10.1021/op0255682
Publikováno v:
Journal of Organometallic Chemistry. 653:269-278
The Suzuki–Miyaura cross-coupling reaction between 1-{3-bromo-4-chloro-5-[1-( R )-fluoropropyl]}phenylpiperazine (( R )- 1b ) and thermally unstable ( o -cyanophenyl)boronic ester 6b in the presence of dichlorobis(triphenylphosphine)palladium and p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d12ba1f28c75a262f78c2db183fae1e7
https://doi.org/10.1016/s0022-328x(02)01175-0
https://doi.org/10.1016/s0022-328x(02)01175-0
Autor:
Takashi Tatsuzawa, Masao Tokuda, Ryo Kanbayashi, Kazuhiko Orito, Mamoru Miyazawa, Hiroshi Suginome
Publikováno v:
The Journal of Organic Chemistry. 65:7495-7500
Treatment of 1-(2'-bromo-3',4'-dialkoxybenzyl)-1,2,3, 4-tetrahydroisoquinoline carbamates, 1a,c, with excess alkyllithium gave 8-oxoberbines, 2a,c, which were successively attacked in situ with another molecule of alkyllithium to give 1,2 and/or 1,4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cd2fdcaec17a0173b7947a2f157c8a1
https://doi.org/10.1021/jo000749s
https://doi.org/10.1021/jo000749s
Publikováno v:
The Journal of Organic Chemistry. 64:6583-6596
6,7,3',4'-Alkoxy-substituted 1-(2'-bromobenzoyl)-3,4-dihydroisoquinoline methiodides 17 were treated with sodium borohydride in methanol or acetic acid to give erythro-1-(2'-bromo-alpha-hydroxybenzyl)-2-methyl-1,2,3,4-tetrahydroisoquinolines 19. Trea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40ebcd90a32cc811472d4ae9451fcf32
https://doi.org/10.1021/jo982451w
https://doi.org/10.1021/jo982451w
Publikováno v:
Tetrahedron. 51:2489-2496
Conversion of alkoxy-substituted benzyl alcohols to the corresponding phthalides by carboxylation via ortho lithiation and bromine-lithium exchange was studied. The method was applied to the key step in the synthesis of phthalideisoquinoline alkaloid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e6d6d14afd38159f376794681c83a8a
https://doi.org/10.1016/0040-4020(95)00003-q
https://doi.org/10.1016/0040-4020(95)00003-q
Publikováno v:
ChemInform. 26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f2a917557295bd6db5410c6017cec7c
https://doi.org/10.1002/chin.199509070
https://doi.org/10.1002/chin.199509070