Zobrazeno 1 - 10
of 209
pro vyhledávání: '"Mamoru Kato"'
Autor:
Bunpei Miyazaki, Toshihide Ueno, Masanaka Sugiyama, Shinya Kojima, Ayumu Arakawa, Kayoko Tao, Kazuki Tanimura, Kouya Shiraishi, Shigehiro Yagishita, Shinji Kohsaka, Mamoru Kato, Nobutaka Kiyokawa, Yasushi Goto, Yasushi Yatabe, Akinobu Hamada, Hiroyuki Mano, Chitose Ogawa, Yosuke Tanaka
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-6 (2023)
Abstract Philadelphia chromosome (Ph)-like acute lymphoblastic leukemia (ALL) is a subset of ALL that demonstrated a high treatment failure rate. One of the hallmarks of Ph-like ALL is PDGFRB gene fusion, with fusion partner proteins often harboring
Externí odkaz:
https://doaj.org/article/adf3815b86234c9bafef361a1583d32a
Autor:
Kana Shimomura, Naoko Hattori, Naoko Iida, Yukari Muranaka, Kotomi Sato, Yuichi Shiraishi, Yasuhito Arai, Natsuko Hama, Tatsuhiro Shibata, Daichi Narushima, Mamoru Kato, Hiroyuki Takamaru, Koji Okamoto, Haruna Takeda
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Chronic inflammation promotes development and progression of colorectal cancer (CRC). To comprehensively understand the molecular mechanisms underlying the development and progression of inflamed CRC, we perform in vivo screening and identif
Externí odkaz:
https://doaj.org/article/82f476bb971d41d59d021cc78cdcafae
Autor:
Mihoko Saito-Adachi, Natsuko Hama, Yasushi Totoki, Hiromi Nakamura, Yasuhito Arai, Fumie Hosoda, Hirofumi Rokutan, Shinichi Yachida, Mamoru Kato, Akihiko Fukagawa, Tatsuhiro Shibata
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Structural variants (SVs) are responsible for driver events in gastric cancer (GC); however, their patterns and processes remain poorly understood. Here, we examine 170 GC whole genomes to unravel the oncogenic structural aberration landscap
Externí odkaz:
https://doaj.org/article/a521e2d770ec44e0b630ad375453251d
Autor:
George Bebis, Mamoru Kato, Mohammad Kohandel, Kathleen Wilkie, Dinler A. Antunes, Ken Chen, Jinzhuang Dou
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Externí odkaz:
https://doaj.org/article/4b20215af54943748379ec7d61eb63be
Autor:
Hanako Ono, Yasuhito Arai, Eisaku Furukawa, Daichi Narushima, Tetsuya Matsuura, Hiromi Nakamura, Daisuke Shiokawa, Momoko Nagai, Toshio Imai, Koshi Mimori, Koji Okamoto, Yoshitaka Hippo, Tatsuhiro Shibata, Mamoru Kato
Publikováno v:
BMC Biology, Vol 19, Iss 1, Pp 1-17 (2021)
Abstract Background Intra-tumor heterogeneity (ITH) encompasses cellular differences in tumors and is related to clinical outcomes such as drug resistance. However, little is known about the dynamics of ITH, owing to the lack of time-series analysis
Externí odkaz:
https://doaj.org/article/31ee633a416145f5b7e9830d0dc2d5e7
Autor:
Shinichi Mizuno, Rui Yamaguchi, Takanori Hasegawa, Shuto Hayashi, Masashi Fujita, Fan Zhang, Youngil Koh, Su-Yeon Lee, Sung-Soo Yoon, Eigo Shimizu, Mitsuhiro Komura, Akihiro Fujimoto, Momoko Nagai, Mamoru Kato, Han Liang, Satoru Miyano, Zemin Zhang, Hidewaki Nakagawa, Seiya Imoto
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Immune reactions in the tumor microenvironment are an important hallmark of cancer, and emerging immune therapies have been proven effective against several types of cancers. To investigate cancer genome-immune interactions and the role of i
Externí odkaz:
https://doaj.org/article/351129f51da84158b681c55273869ced
Autor:
Motoo Nagane, Koichi Ichimura, Ritsuko Onuki, Daichi Narushima, Mai Honda-Kitahara, Kaishi Satomi, Arata Tomiyama, Yasuhito Arai, Tatsuhiro Shibata, Yoshitaka Narita, Takeo Uzuka, Hideo Nakamura, Mitsutoshi Nakada, Yoshiki Arakawa, Takanori Ohnishi, Akitake Mukasa, Shota Tanaka, Toshihiko Wakabayashi, Tomokazu Aoki, Shigeki Aoki, Soichiro Shibui, Masao Matsutani, Keisuke Ishizawa, Hideaki Yokoo, Hiroyoshi Suzuki, Satoshi Morita, Mamoru Kato, Ryo Nishikawa
Publikováno v:
Cancers, Vol 14, Iss 22, p 5522 (2022)
We evaluated the efficacy and safety of bevacizumab beyond progression (BBP) in Japanese patients with newly diagnosed glioblastoma and explored predictors of response to bevacizumab. This phase II study evaluated a protocol-defined primary therapy b
Externí odkaz:
https://doaj.org/article/0bd5bbbae8564ab29264e7e1066c5d9d
Autor:
Kohei Fukuoka, Yonehiro Kanemura, Tomoko Shofuda, Shintaro Fukushima, Satoshi Yamashita, Daichi Narushima, Mamoru Kato, Mai Honda-Kitahara, Hitoshi Ichikawa, Takashi Kohno, Atsushi Sasaki, Junko Hirato, Takanori Hirose, Takashi Komori, Kaishi Satomi, Akihiko Yoshida, Kai Yamasaki, Yoshiko Nakano, Ai Takada, Taishi Nakamura, Hirokazu Takami, Yuko Matsushita, Tomonari Suzuki, Hideo Nakamura, Keishi Makino, Yukihiko Sonoda, Ryuta Saito, Teiji Tominaga, Yasuhiro Matsusaka, Keiichi Kobayashi, Motoo Nagane, Takuya Furuta, Mitsutoshi Nakada, Yoshitaka Narita, Yuichi Hirose, Shigeo Ohba, Akira Wada, Katsuyoshi Shimizu, Kazuhiko Kurozumi, Isao Date, Junya Fukai, Yousuke Miyairi, Naoki Kagawa, Atsufumi Kawamura, Makiko Yoshida, Namiko Nishida, Takafumi Wataya, Masayoshi Yamaoka, Naohiro Tsuyuguchi, Takehiro Uda, Mayu Takahashi, Yoshiteru Nakano, Takuya Akai, Shuichi Izumoto, Masahiro Nonaka, Kazuhisa Yoshifuji, Yoshinori Kodama, Masayuki Mano, Tatsuya Ozawa, Vijay Ramaswamy, Michael D. Taylor, Toshikazu Ushijima, Soichiro Shibui, Mami Yamasaki, Hajime Arai, Hiroaki Sakamoto, Ryo Nishikawa, Koichi Ichimura, on behalf of the Japan Pediatric Molecular Neuro-Oncology Group (JPMNG)
Publikováno v:
Acta Neuropathologica Communications, Vol 6, Iss 1, Pp 1-18 (2018)
Abstract Extensive molecular analyses of ependymal tumors have revealed that supratentorial and posterior fossa ependymomas have distinct molecular profiles and are likely to be different diseases. The presence of C11orf95-RELA fusion genes in a subs
Externí odkaz:
https://doaj.org/article/2057539d6eed448b8618d9a778aeb5fa
Autor:
Endi Xia, Sotaro Kanematsu, Yusuke Suenaga, Asmaa Elzawahry, Hitomi Kondo, Noriko Otsuka, Yasumitsu Moriya, Toshihiko Iizasa, Mamoru Kato, Ichiro Yoshino, Sana Yokoi
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Abstract Copy number gains in cancer genomes have been shown to induce oncogene expression and promote carcinogenesis; however, their role in regulating oncogenic microRNAs (onco-miRNAs) remains largely unknown. Our aim was to identify onco-miRNAs in
Externí odkaz:
https://doaj.org/article/9e94e1852eac42cc81b1c053060701a0
Publikováno v:
Data in Brief, Vol 34, Iss , Pp 106719- (2021)
Dataset contains results of multiple parallel calculations using the tugHall simulator. Output data of simulations are variant allele frequencies for four genes (APC, KRAS, TP53, and PIK3CA) related to colorectal cancer. During each simulation tugHal
Externí odkaz:
https://doaj.org/article/5c2669913ebd43b082d9e1cc3a9b3ec3