Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Mamoru Fujioka"'
Autor:
Shinichiro Nakamura, Hiroko Iijima, Yusuke Shibata, Yutaka Watanuki, Sadanobu Ogawa, Takashi Kumada, Hironori Ichikawa, Mamoru Fujioka, Saki Kataoka, Satoshi Yasuda, Toshifumi Tada, Shinichi Hashinokuchi, Kenji Takeshima, Naoya Fukuda, Kazuyuki Tsujii, Fumihiko Niwa, Hidenori Toyoda
Publikováno v:
Hepatology research : the official journal of the Japan Society of HepatologyReferences. 50(12)
AIM A new method has recently been developed for diagnosing hepatic steatosis based on attenuation measurement using ultrasound. We investigated the ability of attenuation imaging (ATI) to detect steatosis that was identified by proton density fat fr
Autor:
Yayoi Shihahara, Yoshihiko Okamoto, Marie T. Mooney, Shinnichiro Suzuki, Kyoko Yamamoto, Mamoru Fujioka, Shuhei Deguchi, Toshiji Tada, Tsutomu Yasuda
Publikováno v:
Journal of Inorganic Biochemistry. 65:191-197
(Z)-2-(2-aminothiazol-4-yl)-N-(2-hydroxyethyl)-2-(hydroxyimino)acetamide (HL) has been employed as a model compound for an orally active cephalosporin antibiotic, Cefdinir (CFDN). A binuclear copper(II) complex Cu2L4 (1) has been obtained from an aqu
Degradation Kinetics and Isomerization of Cefdinir, a New Oral Cephalosporin, in Aqueous Solution. 1
Autor:
Yoshihiro Namiki, Junichi Matsushita, Mamoru Fujioka, Yoshihiko Okamoto, Kuniko Kiriyama, Tsutomu Yasuda
Publikováno v:
Journal of Pharmaceutical Sciences. 85:976-983
Hydrolytic degradation products of cefdinir were studied in acidic (pH 1), neutral (pH 6), and basic (pH 9) solutions. Seven major degradation products were isolated by preparative and/or high-performance liquid chromatography and characterized by UV
Autor:
Yoshihiro Namiki, Tsutomu Yasuda, Junichi Matsushita, Mamoru Fujioka, Yoshihiko Okamoto, Kuniko Kiriyama
Publikováno v:
Journal of Pharmaceutical Sciences. 85:984-989
Hydrolysis of cefdinir leads to pH-dependent isomerizations and beta-lactam ring-opening. Lactam ring opened gamma-lactones were produced as a mixture of four diastereoisomers based on the lactone methyl, and C-6 isomerizations in acidic to neutral s
Autor:
Tsutomu Yasuda, Kohji Itoh, Yoshihiro Namiki, Junichi Matsushita, Yoshihiko Okamoto, Mamoru Fujioka
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 14:739-748
The validation of the HPLC method used for the determination of cefdinir and its related substances is described. The developed method was specific and stability-indicating and provided a linear response with concentration. The system and method prec
Autor:
Tsutomu Yasuda, Shuhei Deguchi, Yoshihiko Okamoto, Marie T. Mooney, Mamoru Fujioka, Toshiji Tada
Publikováno v:
Chemical and Pharmaceutical Bulletin. 43:374-377
Cefdinir (CFDN) is an orally active, semisynthetic cephalosporin antibiotic and its structure is characterized by an oxyimino side chain which is able to form complexes with various metal ions. We observed that bioavailability of CFDN in dogs was red
Autor:
Yuan-Ying Liu, Masakatsu Sudo, Mamoru Fujioka, Yoshiharu Kikawa, Akio Nakai, Yosuke Shigematsu
Publikováno v:
Pediatrics International. 36:112-115
Publikováno v:
Organic Mass Spectrometry. 25:80-82
Publikováno v:
Clinica chimica acta; international journal of clinical chemistry. 203(2-3)
Isovaleric acidemia is an autosomal recessive inherited disorder due to a deficiency of isovaleryl-CoA dehydrogenase. Although two clinically different types of this disease, an acute neonatal form and a chronic intermittent form, have been reported,
Publikováno v:
Biomedicalenvironmental mass spectrometry. 19(13)
This investigation reports the low-energy collision-induced dissociation of the protonated molecules of polyamino alcohols, formed by chemical reduction of synthetic peptides and N-terminal blocked peptides, in order to evaluate its potential for pep