Superantigen-reactive CD4+ T cells are required to stimulate B cells after infection with mouse mammary tumor virus

Autor: Hans Acha-Orbea, H R MacDonald, A N Shakhov, Shozo Izui, Leonardo Scarpellino, Werner Held, Gary A. Waanders

Publikováno v: Journal of Experimental Medicine, vol. 177, no. 2, pp. 359-366
The Journal of Experimental Medicine
Journal of Experimental Medicine, Vol. 177, No 2 (1993) pp. 359-366

Superantigens are defined by their ability to stimulate a large fraction of T cells via interaction with the T cell receptor (TCR) V beta domain. Endogenous superantigens, classically termed minor lymphocyte-stimulating (Mls) antigens, were recently

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4832135b6cc10ec5e082b3970fb1dc8
https://doi.org/10.1084/jem.177.2.359

Tissue-specific and ubiquitous factors binding next to the glucocorticoid receptor modulate transcription from the mouse mammary tumor virus promoter

Autor: C Cavin, E Buetti

Publikováno v: Journal of Virology, vol. 69, no. 6, pp. 3759-70

Steroid hormones complexed with their receptors play an essential role in the regulation of mouse mammary tumor virus (MMTV) transcription. However, the need for additional tissue-specific regulatory factors is suggested by the lack of virus expressi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53ba3d880e995a5c11c6e856b90403c5
https://serval.unil.ch/notice/serval:BIB_AB36D978AE75

An exogenous mouse mammary tumor virus with properties of Mls-1a (Mtv-7)

Autor: Roland Luethy, Leonardo Scarpellino, Gary A. Waanders, H R MacDonald, Hans Acha-Orbea, J P Kraehenbuhl, A N Shakhov, Werner Held

Publikováno v: Journal of Experimental Medicine, vol. 175, no. 6, pp. 1623-1633
The Journal of Experimental Medicine

The classical minor lymphocyte stimulating (Mls) antigens, which induce a strong primary T cell response in vitro, are closely linked to endogenous copies of mouse mammary tumor viruses (MMTV). Expression of Mls genes leads to clonal deletion of T ce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::494447036df57f55a1536b53daa4d9c0
https://serval.unil.ch/notice/serval:BIB_34B1C10DA8A9

Characterization of endogenous and exogenous mouse mammary tumor virus proviral DNA with site-specific molecular clones

Autor: E Buetti, B Groner, H Diggelmann, N E Hynes

Publikováno v: Journal of Virology, vol. 36, no. 3, pp. 734-45

Restriction fragments of the mouse mammary tumor virus (MMTV) proviral DNA were obtained by molecular cloning procedures. A 4-kilobase fragment delimited by two PstI sites was isolated from unintegrated, linear MMTV DNA and amplified in the pBr322 pl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69fa49151a538fd8cefd0a7beece23cc
https://doi.org/10.1128/jvi.36.3.734-745.1980

Nucleotide sequence of the 5′ noncoding region and part of thegaggene of mouse mammary tumor virus; identification of the 5′ splicing site for subgenomic mRNAs

Autor: J. Firzlaff, H. Diggelmann, Nicolas Fasel, E. Buetti, K. Pearson

Publikováno v: Nucleic Acids Research, vol. 11, no. 20, pp. 6943-6955

We have determined the sequence of the first 1371 nucleotides at the 5' end of the genome of mouse mammary tumor virus using molecularly cloned proviral DNA of the GR virus strain. The most likely initiation codon used for the gag gene of mouse mamma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1999efc8831f1171288db4e737bbcbfe
https://doi.org/10.1093/nar/11.20.6943