Zobrazeno 1 - 10
of 475
pro vyhledávání: '"Mammalian embryology"'
Autor:
Marta Miret-Cuesta, Queralt Tolosa-Ramon, Hanna-Maria Häkkinen, Stefan Wieser, Senda Jiménez-Delgado, Christopher N. Wyatt, Manuel Irimia, Andrew Callan-Jones, Esteban Hoijman, Verena Ruprecht
Publikováno v:
Nature. 590:618-623
Errors in early embryogenesis are a cause of sporadic cell death and developmental failure1,2. Phagocytic activity has a central role in scavenging apoptotic cells in differentiated tissues3-6. However, how apoptotic cells are cleared in the blastula
Autor:
Maxime Gasnier, Hongmei Wang, Maté Biro, Hui Yi Grace Lim, Yiming Wang, Piotr Tetlak, Yanina Daniela Alvarez, Stephanie Bissiere, Nicolas Plachta
Publikováno v:
Nature. 585:404-409
To implant in the uterus, the mammalian embryo first specifies two cell lineages: the pluripotent inner cell mass that forms the fetus, and the outer trophectoderm layer that forms the placenta1. In many organisms, asymmetrically inherited fate deter
Autor:
Jie Dong, Lin He, Lin Zhao, Jian Mu, Lei Wang, Jing Fu, Zhongyuan Yao, Qing Sang, Zhihua Zhang, Bin Li, Yanping Kuang, Juanzi Shi, Xiaoyan Mao, Ling Wu, Shuai Liu, Wenjing Wang, Zheng Yan, Xiaoxi Sun, Yao Xu, Qiaoli Li, Weijie Wang, Biaobang Chen, Lihua Sun, Songguo Xue, Li Jin, Jing Du, Xiaozhen Liang
Publikováno v:
Protein & Cell, Vol 11, Iss 12, Pp 921-927 (2020)
Protein & Cell
Protein & Cell
Autor:
Xi Dai, Zongyong Ai, Zhigang Zhao, Yonggang Li, Yu Yin, Dan Wu, Kui Duan, Yuyu Niu, Jingjing He, Weizhi Ji, Zhouchun Shang, Tianqing Li, Yun Zheng, Yanping Ma, Junqiang Guo, Shuchao Ren, Yun Bai, Lifeng Xiang
Publikováno v:
Nature. 577:537-542
Our understanding of how human embryos develop before gastrulation, including spatial self-organization and cell type ontogeny, remains limited by available two-dimensional technological platforms1,2 that do not recapitulate the in vivo conditions3
Autor:
Kristin M. Ackerman, Will LeFever, Martina Krone, Ryan Hesterman, Camryn Holihan, Ryan Stewart, Shannon Rose
Publikováno v:
Journal of Microbiology & Biology Education
Journal of Microbiology & Biology Education, Vol 22, Iss 3 (2021)
Journal of Microbiology & Biology Education, Vol 22, Iss 3 (2021)
In classroom studies of mammalian embryology, students must fully grasp the cellular and tissue remodeling needed to initiate gastrulation to ensure comprehension of forthcoming developmental processes such as tissue specification and organogenesis.
Publikováno v:
Development
Development, 147(15):185579. Company of Biologists Ltd
Development, 147(15):185579. Company of Biologists Ltd
Fluid flow is a powerful morphogenic force during embryonic development. The physical forces created by flowing fluids can either create morphogen gradients or be translated by mechanosensitive cells into biological changes in gene expression. In thi
Autor:
Greg FitzHarris, Lia Mara Gomes Paim
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Nature Communications
Nature Communications
Tetraploidisation is considered a common event in the evolution of chromosomal instability (CIN) in cancer cells. The current model for how tetraploidy drives CIN in mammalian cells is that a doubling of the number of centrioles that accompany the ge
Publikováno v:
Nature Reviews Molecular Cell Biology
Nature Reviews Molecular Cell Biology, Nature Publishing Group, 2019, 20 (10), pp.590-607. ⟨10.1038/s41580-019-0159-6⟩
Nature Reviews Molecular Cell Biology, Nature Publishing Group, 2019, 20 (10), pp.590-607. ⟨10.1038/s41580-019-0159-6⟩
DNA methylation is of paramount importance for mammalian embryonic development. DNA methylation has numerous functions: it is implicated in the repression of transposons and genes, but is also associated with actively transcribed gene bodies and, in
Autor:
Xiaoping Zhong, Wancong Zhang, Shijie Tang, Jiasheng Chen, Weijie Liang, Hanxing Zhao, Jianda Zhou, Lungang Shi, Zhiwei Shen, Yue Xing
Publikováno v:
Molecular Medicine Reports
The aim of the present study was to determine the association between maternal metabolism and development of the fetal palate, and to suggest a potential non‑invasive prenatal diagnostic method for fetal cleft palate (CP). Dexamethasone (DXM) was u