Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Mami Tei"'
Autor:
Mami Tei, Tadamitsu Kishimoto, Praveen K Dubey, Kishan K. Nyati, Yohannes Gemechu, Haruhiko Miyata, Barry Ripley, Taisuke Nakahama, David Millrine
Publikováno v:
International Immunology. 28:307-315
Thalidomide and its derivatives, collectively referred to as immunomodulatory drugs (IMiDs), are effective inhibitors of inflammation and are known to inhibit TLR-induced TNFα production. The identification of Cereblon as the receptor for these comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::140e28b326db8c39e29b3677f377f59d
https://doi.org/10.1093/intimm/dxw005
https://doi.org/10.1093/intimm/dxw005
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 113(38)
Immunomodulatory drugs (IMiDs) are a family of compounds derived from thalidomide. Binding of the IMiD molecule to the Lon protease Cereblon initiates the degradation of substrates via the ubiquitin proteasome pathway. Here, we show that Cereblon for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7fb7bd79c70842b4006c65ce53440e4
https://pubmed.ncbi.nlm.nih.gov/27601648
https://pubmed.ncbi.nlm.nih.gov/27601648
Publikováno v:
Retrovirology
HTLV-1 infection leads to adult T-cell leukemia (ATL) after long latent infection period. We have established an HTLV-1-infected humanized NOG mouse model to analyze the mechanism of ATL development. Humanized mice were inoculated with Jurkat-based H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b78d234e2bf7d3047fb50daa5f9788c
https://doi.org/10.1186/1742-4690-11-s1-p42
https://doi.org/10.1186/1742-4690-11-s1-p42
Publikováno v:
Retrovirology
HTLV-1 infection of humanized NOG mice has been demonstrated to recapitulate the development of ATL-like symptoms within several months of infection. Infected human T-cells in these mice start to proliferate vigorously in a couple weeks after infecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7aa3c4a86d4cc0d5b92c3ce0b476f57e
https://doi.org/10.1186/1742-4690-11-s1-p43
https://doi.org/10.1186/1742-4690-11-s1-p43
Autor:
Takaharu Ueno, Mami Tei, Kenta Tezuka, Runze Xun, Norihiro Takenouchi, Masakazu Tanaka, Jun-ichi Fujisawa
Publikováno v:
Blood. 123(3)
Human T-cell leukemia virus type 1 (HTLV-1) is causally associated with adult T-cell leukemia (ATL), an aggressive T-cell malignancy with a poor prognosis. To elucidate ATL pathogenesis in vivo, a variety of animal models have been established; howev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06de5f125e990ba749fbbf69047ef77b
https://pubmed.ncbi.nlm.nih.gov/24434991
https://pubmed.ncbi.nlm.nih.gov/24434991
Publikováno v:
Retrovirology
Humanized mice (huNOG) established by the intrabone marrow transplantation of NOG-SCID mouse with CD133+ hematopoietic stem cells purified from human cord blood were infected with HTLV-1 in vivo by peritonial injection of g-ray-irradiated MT-2 cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fde2b6c32a3bf4acb15e2c615e7e97a
https://doi.org/10.1186/1742-4690-8-s1-a13
https://doi.org/10.1186/1742-4690-8-s1-a13
Autor:
Kenta Tezuka, Runze Xun, Mami Tei, Jun-ichi Fujisawa, Takaharu Ueno, Norihiro Takenouchi, Masakazu Tanaka
Publikováno v:
Retrovirology, Vol 8, Iss Suppl 1, p A14 (2011)
Retrovirology
Retrovirology
Tax has pleiotropic actions that induce proliferation and inhibit apoptosis of T-cells and thus is considered to play a critical role in leukemogenesis. However, Tax expression is frequently lost in fresh adult T-cell leukemia (ATL) cells by genetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::325daee85eb008f8a80a5a2ebf4b7fce
https://doaj.org/article/8500e55ec3974322b3780ddcaab91fd1
https://doaj.org/article/8500e55ec3974322b3780ddcaab91fd1
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 9/20/2016, Vol. 113 Issue 38, p10625-10630, 6p
Autor:
Millrine, David, Haruhiko Miyata, Mami Tei, Dubey, Praveen, Nyati, Kishan, Taisuke Nakahama, Yohannes Gemechu, Ripley, Barry, Tadamitsu Kishimoto
Publikováno v:
International Immunology; Jun2016, Vol. 28 Issue 6, p307-315, 9p
Autor:
Kenta Tezuka1, Runze Xun1, Mami Tei1, Takaharu Ueno1, Masakazu Tanaka1, Norihiro Takenouchi1, Jun-ichi Fujisawa1 fujisawa@hirakata.kmu.ac.jp
Publikováno v:
Blood. 1/16/2014, Vol. 123 Issue 3, p346-355. 10p.