Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Mami Osawa"'
Autor:
Takashi Ushiki, Tomoharu Mochizuki, Mami Osawa, Katsuya Suzuki, Tetsuhiro Tsujino, Taisuke Watanabe, Carlos Fernando Mourão, Tomoyuki Kawase
Publikováno v:
Journal of Functional Biomaterials, Vol 15, Iss 4, p 98 (2024)
Plasma gel (PG) is a protein matrix prepared from platelet-poor plasma and can be utilized as a drug carrier for controlled release. We previously demonstrated its applicability as a carrier of polyphosphate. Epigallocatechin-3-gallate (EGCG) is the
Externí odkaz:
https://doaj.org/article/616944d56baf4f8780f3ed0523b0d011
Autor:
Yasunobu Matsuda, Toshifumi Wakai, Masayuki Kubota, Mami Osawa, Masaaki Takamura, Satoshi Yamagiwa, Yutaka Aoyagi, Ayumi Sanpei, Shun Fujimaki
Publikováno v:
The Scientific World Journal, Vol 2013 (2013)
Background. Phosphorylated histone H2AX (γ-H2AX) is a potential regulator of DNA repair and is a useful tool for detecting DNA damage. To evaluate the clinical usefulness of γ-H2AX in hepatocellular carcinoma (HCC), we measured the level of γ-H2AX
Externí odkaz:
https://doaj.org/article/a5ad762b360e478b8d732ec1adb7a2d9
Publikováno v:
Anticancer Research. 42:745-757
Publikováno v:
Anticancer Research. 41:645-660
Sorafenib is a multikinase inhibitor approved as a first-line therapy for hepatocellular carcinoma. This study examined the sorafenib resistance mechanism.Hepatoma HepG2 cells were exposed to sorafenib, and the biological activity of the conditioned
Publikováno v:
Anticancer research. 42(2)
Tumour repopulation is a major obstacle for successful cancer treatment. This study investigated whether anticancer agents contribute to tumour repopulation in TP53-mutated bile duct cancer cells.TP53-mutated HuCCT1 and HuH28 cells were exposed to an
Publikováno v:
Electrochemistry. 85:656-659
Publikováno v:
Journal of Pediatric Surgery. 48:2416-2424
Introduction In experiments involving tracheal wall defects in rabbits, metallic coil stents inevitably induce granulation formation in the defects. We examined the involvement of the mammalian target of rapamycin (mTOR) signaling pathway in granulat
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 14, Iss 12, Pp 23499-23515 (2013)
Volume 14
Issue 12
Pages 23499-23515
International Journal of Molecular Sciences, Vol 14, Iss 12, Pp 23499-23515 (2013)
Volume 14
Issue 12
Pages 23499-23515
Non-alcoholic steatohepatitis (NASH) is a recently identified chronic liver disease, which progresses to liver cirrhosis and hepatocellular carcinoma (HCC). As the number of patients studied to date has been limited, clinically useful prognostic biom
Autor:
Munehiro Sato, Satoshi Yamagiwa, Masayuki Kubota, Shun Fujimaki, Ayumi Sanpei, Yasunobu Matsuda, Masaaki Takamura, Toshifumi Wakai, Yutaka Aoyagi, Mami Osawa
Publikováno v:
Journal of Gastroenterology and Hepatology. 28:1047-1055
Background and Aim Transforming growth factor-β (TGF-β) has been shown to play a central role in the promotion of cell motility, but its functional mechanism has remained unclear. With the aim of investigating the diagnostic and treatment modalitie
Autor:
Mami Osawa, Masaaki Takamura, Ayumi Sanpei, Toshifumi Wakai, Takafumi Ichida, Satoshi Yamagiwa, Yasunobu Matsuda, Takuya Genda, Masayuki Kubota, Yutaka Aoyagi, Shun Fujimaki
Publikováno v:
Medical Molecular Morphology. 46:185-192
It is well accepted that cell cycle regulators are strongly implicated in the progression of cancer development. p16 and p27 are potent cyclin-dependent kinase (CDK) inhibitors involved in G1 phase progression, and are regarded as adverse prognostic